Navigation Links
Xceed Molecular to Launch New Inflammation Xpress Chip(TM)for the Ziplex(R) Automated Gene-Expression Analysis System at Clinical Lab Expo 2008, Booth 2155
Date:7/29/2008

WASHINGTON and WELLESLEY, Mass., July 29 /PRNewswire/ -- Xceed Molecular, a pioneer in the development of cost-effective, easy-to-use gene-expression analysis systems, will launch its new Inflammation Xpress Chip, a pre-configured array for use with the company's Ziplex automated gene-expression analysis system, at the 2008 AACC/ASCLS Clinical Lab Expo (booth 2155). The Clinical Lab Expo opens today at Walter E. Washington Convention Center in Washington, DC.

"With our expanding portfolio of Xpress Chips, Xceed is creating another building block to accelerate the development of novel multiplex tests," said Xceed President and CEO David Deems. "Inflammation is a complex biological response to a wide range of tissue injuries, harmful pathogens, and disorders. This response is usually associated with increased levels of cytokines, cytokine receptors, adhesion molecules, and other immuno-regulatory factors. Our Inflammation Xpress Chip is a powerful tool to enable investigators to discover and characterize molecular profiles associated with inflammatory responses, to study the effects of therapeutics in mitigating immune responses, and to study auto-immune diseases in general. Expression changes in specific genes and pathways represented on the Inflammation Xpress Chip may help in monitoring patient responses to therapy or in predicting the ability of a therapeutic (e.g. Methotrexate, a TNF-alpha inhibitor, or a novel monoclonal antibody-based compound) to block disease-related inflammation events. The Inflammation Xpress Chip gene list was identified from scientific reports of genes differentially expressed in common inflammatory conditions.

At the core of the Ziplex System is the TipChip - a single-use disposable device consisting of a square Flow-Thru Chip(R) mounted to a polycarbonate tube. Unlike two-dimensional arrays, the unique 3D Flow-Thru Chip design enables active transport of targets to probes. Molecular interactions occur within the three-dimensional matrix of these channels as target solutions pass through. The chip is made of porous silicon with microchannels that extend from the upper to the lower surface of the chip. Capture reagents are attached to the walls of distinct groups of microchannels ("spots") and target molecules are captured as sample flows through the channels. Multiple capture reagents are deposited in a grid to permit parallel analysis of up to 484 spots per chip ("features"). This approach facilitates the interaction between target molecules and immobilized probes, resulting in hybridization times that are three- to four-times faster.

Xceed offers two types of TipChips - preconfigured (Xpress Chips) and custom (Autograph Chips(TM)). Xceed's preconfigured Xpress Chips (like the new Inflammation Xpress Chip) contain published genes of interest for common pathways or disease processes. They provide a ready-made solution, for research only, to assess specific transcript profiles. Xceed offers several preconfigured arrays. Xceed's Metabolic Xpress Chip offers genes of interest for investigators exploring metabolic pathways and can be used to investigate differential expression associated with diseases of the metabolic system, such as obesity, muscle disorders, and other metabolic disorders. Xceed also offers the Breast and Colon Cancer Xpress Chips, and we have a number of other TipChip arrays in development for a range of cancers, including prostate, lung, and melanoma. Xceed manufactures custom Autograph Chips with the customer's specific gene signatures of interest. Each array is ideal for focused disease biomarkers comprising up to 120 genes, allowing for three replicates per probe. Focused content allows cost-effective analysis of relevant markers in disease-process research investigations.

About Xceed Molecular (http://www.XceedMolecular.com)

Xceed's vision is to advance molecular diagnostics by successfully translating novel multiplex tests into routine clinical practice and to create robust diagnostic solutions to improve disease outcomes. Our products comprise the Ziplex(R) System for automated gene-expression analysis (available in the US and Canada for research use only), gene expression services, and pre-configured arrays - Xpress Chips. Xceed is also developing multiplexed genomic tests for the Ziplex platform, both internally and with strategic partners. Xceed's R&D and manufacturing are headquartered in Toronto, Ontario, with executive offices in Wellesley, Massachusetts.


'/>"/>
SOURCE Xceed Molecular
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. Kiwa Bio-Tech Revenues for 1st Half Exceed $3.25 Million
2. CrossFire Beilstein Database Exceeds Ten Million Compounds
3. CNCA Exceeds Standards in Nutritional Supplement Quality, Protects Public
4. Center for Molecular Medicine Offers Xceed Ziplex(TM) Services to Research Community
5. AMDL Signs 100 Strategic Cooperation Agreements in China for Its JPGreen Clinics; Gross Sales Per Each Location Could Exceed $400,000
6. Cephalons 2007 Results Exceed Full Year Sales and Earnings Guidance
7. Osteotech Reports 2007 Full Year and Fourth Quarter Financial Results; Full Year Revenue of $104.3 Million Exceeds $100 Million Milestone; Diluted Earnings Per Share Was $.15 in 2007
8. Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million
9. Xceed Molecular Features Ziplex(R) Automated Gene-Expression System at the Biomarker World Congress, Booth 16
10. Xceed Molecular Grants Gen-Probe License to Xceeds Flow-Thru Chip(R) Technology for Multiplex Molecular Diagnostics
11. Center for Molecular Medicine Only Regional Provider of Test Suggested in FDA Alert on Prescribing Codeine to Nursing Mothers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... 23, 2016  The Prostate Cancer Foundation (PCF) is pleased to ... faster cures for prostate cancer. Members of the Class of 2016 were selected ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... OTTAWA, ON (PRWEB) , ... June 23, 2016 , ... ... former DNA Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA ... joining the STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
(Date:6/23/2016)... ... 23, 2016 , ... Velocity Products, a division of Morris ... optimized exclusively for Okuma CNC machining centers at The International Manufacturing Technology Show, ... several companies with expertise in toolholding, cutting tools, machining dynamics and distribution, Velocity ...
Breaking Biology Technology:
(Date:5/20/2016)...  VoiceIt is excited to announce its new ... By working together, VoiceIt and VoicePass will offer ... take slightly different approaches to voice biometrics, collaboration ... usability. Both ... "This marketing and technology partnership allows ...
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
Breaking Biology News(10 mins):