Xceed Molecular to Launch New Inflammation Xpress Chip(TM)for the Ziplex(R) Automated Gene-Expression Analysis System at Clinical Lab Expo 2008, ...( WASHINGTON and WELLESLEY Mass. Ju...)

WASHINGTON and WELLESLEY, Mass., July 29 /PRNewswire/ -- Xceed Molecular, a pioneer in the development of cost-effective, easy-to-use gene-expression analysis systems, will launch its new Inflammation Xpress Chip, a pre-configured array for use with the company's Ziplex automated gene-expression analysis system, at the 2008 AACC/ASCLS Clinical Lab Expo (booth 2155). The Clinical Lab Expo opens today at Walter E. Washington Convention Center in Washington, DC.

"With our expanding portfolio of Xpress Chips, Xceed is creating another building block to accelerate the development of novel multiplex tests," said Xceed President and CEO David Deems. "Inflammation is a complex biological response to a wide range of tissue injuries, harmful pathogens, and disorders. This response is usually associated with increased levels of cytokines, cytokine receptors, adhesion molecules, and other immuno-regulatory factors. Our Inflammation Xpress Chip is a powerful tool to enable investigators to discover and characterize molecular profiles associated with inflammatory responses, to study the effects of therapeutics in mitigating immune responses, and to study auto-immune diseases in general. Expression changes in specific genes and pathways represented on the Inflammation Xpress Chip may help in monitoring patient responses to therapy or in predicting the ability of a therapeutic (e.g. Methotrexate, a TNF-alpha inhibitor, or a novel monoclonal antibody-based compound) to block disease-related inflammation events. The Inflammation Xpress Chip gene list was identified from scientific reports of genes differentially expressed in common inflammatory conditions.

At the core of the Ziplex System is the TipChip - a single-use disposable device consisting of a square Flow-Thru Chip(R) mounted to a polycarbonate tube. Unlike two-dimensional arrays, the unique 3D Flow-Thru Chip design enables active transport of targets to probes. Molecular interactions occur within the thr
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