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Women More Likely Than Men to Avoid Amputation After Minimally Invasive Therapy for Blocked Leg Arteries
Date:1/18/2010

Women with below-the-knee artery blockages fare better than men when treated with minimally invasive endovascular therapy. Two years after endovascular treatment, 88 percent of women avoided amputation compared to 83 percent of men, according to a study of 277 patients.

(PRWEB) January 18, 2010 -- Women who are at risk of lower-leg amputation fare even better than men when they have minimally invasive treatment to open up the blocked arteries causing the problem, suggest results of a study being presented at the 22nd annual International Symposium on Endovascular Therapy (ISET).

Two years after receiving endovascular treatment – including angioplasty, stenting and atherectomy – nearly nine out of 10 (88 percent) of women in the study had avoided amputation, versus 83 percent of men.

“This study is the first to compare the outcomes of men and women being treated for blocked lower-leg arteries with endovascular therapy,” said Tejas Shah, M.D., research fellow at Mt. Sinai Medical Center, New York. “The results suggest endovascular therapy should be strongly considered in women with blocked arteries below the knee.”

The retrospective study involved review of all such procedures that took place at Mt. Sinai between July 1999 and November 2009 and included 152 men and 125 women. After two years, 46 percent of treated leg arteries in women remained open, compared to 30 percent in men. However, women experienced higher rates of blood clots forming at the access site of the treatment: nine percent of women vs. 0.6 percent of men experienced clotting, which is treated with blood thinners and may require a longer stay in the hospital.

Narrowed and blocked leg arteries are a common symptom of peripheral arterial disease (PAD). Like heart arteries, leg arteries can become clogged by plaque (fatty deposits) that slows or stops
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