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With the BEAUTIFUL Results, Procoralan* (ivabradine) is the First Antianginal Treatment Shown to Reduce Myocardial Infarction (Heart Attack) and Revascularisation in Stable Coronary Patients
Date:8/31/2008


MUNICH, Germany, August 31 /PRNewswire/ --

Press conference The BEAUTIFUL study: a step further in

title Coronary Artery Disease

ESC Hotline Title: The BEAUTIFUL study: efficacy of

session title ivabradine in reduction of cardiovascular

events among patients with stable coronary

artery disease and left ventricular

dysfunction

ESC Hotline 31st August 2008, 11:18 - 11:31 AM

session time

Press conference 9.00-10.00

Timing

Executive 31st August 2008: 9.00 - 10.30 AM

committee members

available for

interview

The results of the much awaited BEAUTIFUL (morBidity-mortality EvAlUaTion of the IF inhibitor ivabradine in patients with CAD and left ventricULar dysfunction) trial have shown that coronary artery disease (CAD) patients with left ventricular dysfunction (LVD) and a heart rate more than 70 bpm have a significantly higher risk of cardiovascular death and other cardiovascular events and in these patients (heart rate above 70 bpm) treatment with ivabradine further reduces the risk of the most important coronary events such as fatal and non-fatal myocardial infarction and coronary revascularisation by one third, even when these patients are already receiving optimal therapy. Commenting after the results presentation, the Chairman of the BEAUTIFUL Executive Committee, Prof Kim Fox said, "Ivabradine was always known to relieve ischemia. With the BEAUTIFUL results, ivabradine is the first antianginal treatment shown to reduce myocardial infarction and revascularisation and to have a good tolerability profile even when used with other drugs. This is the gold standard for any antianginal, anti-ischemic drug."

The BEAUTIFUL trial was initiated in December 2004, under the guidance of an independent Executive Committee with the f
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SOURCE Executive Committee of Beautiful Study
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