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William P. Sheridan Appointed Chief Medical Officer of BioCryst Pharmaceuticals
Date:6/18/2008

BIRMINGHAM, Ala., June 18 /PRNewswire-FirstCall/ -- BioCryst Pharmaceuticals (Nasdaq: BCRX) today announced that William P. Sheridan, MB BS, has been appointed Chief Medical Officer of BioCryst, effective July 1, 2008. Dr. Sheridan is a seasoned biotechnology professional, most recently serving as Vice President of North American Medical Affairs at Amgen, Inc. He replaces interim Chief Medical Officer Dr. Tom Simon, who has been with the Company since January of this year. Dr. Simon will remain with the Company through December 31, 2008 to ensure a smooth transition of activities.

Jon P. Stonehouse, Chief Executive Officer of BioCryst, stated, "We are pleased to announce Bill's appointment and are grateful to Tom for the enormous contributions he has made at BioCryst. This is a particularly important time for BioCryst, as we move forward with our clinical programs for both peramivir, our product for seasonal and life-threatening influenza, and forodesine HCl, being developed for oncology indications. Bill has extensive experience bringing novel therapeutics to market and he will play an important leadership role in both driving our clinical programs forward toward registration, and identifying other novel candidates for future development from our discovery unit."

During his 15-year tenure at Amgen, Dr. Sheridan organized and led the company's US Medical Affairs function, making significant contributions to the successful launch of many compounds, including Aranesp(R), Enbrel(R), Kineret(R), Neulasta(R) and Sensipar(R). In addition to his most recent position at Amgen, Dr. Sheridan held titles at the Vice President level in International Medical Affairs, Global Health Economics and Outcomes Research, US Medical Affairs, and
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