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When to Wait and When to Treat? New Program Will Search for Biomarkers in Men With Prostate Cancer to Help Find an Answer
Date:5/2/2008

samples will be located at the Hutchinson Center. The repository will be funded by the Canary Foundation. NCI's Early Detection Research Network (EDRN), the federal agency that is partnering with the Canary Foundation, will establish disease-specific Common Data Elements, a biospecimen management system and a protocol oversight program. The EDRN data management and coordinating center is based at the Hutchinson Center under the direction of Zideng Feng, Ph.D., a member of the Hutchinson Center's Public Health Sciences Division.

The samples will be tested for candidate biomarkers -- proteins in the blood -- that can signal when indolent disease has progressed to more aggressive illness. Such biomarkers could help physicians better determine when to initiate treatment versus watchful waiting.

Each of the study institutions also has a "retrospective" tissue collection of samples taken from unrelated studies. These will also be examined to ascertain the accuracy of predictive biomarkers.

"We are proud to launch this new study with EDRN and with the participation of leading research institutes," said Nelson, who is also a professor of oncology at the University of Washington School of Medicine. "Through collaboration we can make bigger strides in providing better, more individualized treatment for prostate-cancer patients."

The Canary Foundation is providing initial funding for the Prostate Active Surveillance Study. The five institutions that will enroll patients are University of Washington, Stanford University, University of California at San Francisco, University of British Columbia and University of Texas Health Science Center in San Antonio.

About Fred Hutchinson Cancer Research Center

At Fred Hutchinson Cancer Research Center, interdisciplinary teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Our researchers, including three Nobel laurea
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SOURCE Fred Hutchinson Cancer Research Center
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