samples will be located at the Hutchinson Center. The repository will be
funded by the Canary Foundation. NCI's Early Detection Research Network
(EDRN), the federal agency that is partnering with the Canary Foundation,
will establish disease-specific Common Data Elements, a biospecimen
management system and a protocol oversight program. The EDRN data
management and coordinating center is based at the Hutchinson Center under
the direction of Zideng Feng, Ph.D., a member of the Hutchinson Center's
Public Health Sciences Division.
The samples will be tested for candidate biomarkers -- proteins in the
blood -- that can signal when indolent disease has progressed to more
aggressive illness. Such biomarkers could help physicians better determine
when to initiate treatment versus watchful waiting.
Each of the study institutions also has a "retrospective" tissue
collection of samples taken from unrelated studies. These will also be
examined to ascertain the accuracy of predictive biomarkers.
"We are proud to launch this new study with EDRN and with the
participation of leading research institutes," said Nelson, who is also a
professor of oncology at the University of Washington School of Medicine.
"Through collaboration we can make bigger strides in providing better, more
individualized treatment for prostate-cancer patients."
The Canary Foundation is providing initial funding for the Prostate
Active Surveillance Study. The five institutions that will enroll patients
are University of Washington, Stanford University, University of California
at San Francisco, University of British Columbia and University of Texas
Health Science Center in San Antonio.
About Fred Hutchinson Cancer Research Center
At Fred Hutchinson Cancer Research Center, interdisciplinary teams of
world-renowned scientists and humanitarians work together to prevent,
diagnose and treat cancer, HIV/AIDS and other diseases. Our researchers,
including three Nobel laurea
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|SOURCE Fred Hutchinson Cancer Research Center|
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