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Watson Pharmaceuticals Announces New Research Showing RAPAFLO(R) (silodosin) Improves Outcomes for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Date:5/17/2011

WASHINGTON, May 17, 2011 /PRNewswire/ -- New data presented today show that RAPAFLO(R) (silodosin) significantly reduced symptoms of moderate to severe chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).  In the study presented at the annual meeting of the American Urological Association, RAPAFLO(R) also significantly improved urinary symptoms as well as quality of life.

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition characterized by persistent discomfort in the lower pelvic area and can have significant impact on quality of life. Symptoms can be severe and include painful and frequent urination and difficult or painful ejaculation. By definition, this type of prostatitis is not associated with a bacterial infection, and the cause is unknown. As many as 10 percent of men in North America have had or will have experienced prostatitis symptoms, and 90 percent of them have CP/CPPS. Evaluated in this trial for CP/CPPS, RAPAFLO(R) is a uniquely selective alpha blocker approved for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH), commonly referred to as an enlarged prostate.

"In this well-controlled, double-blind study, RAPAFLO(R) has demonstrated significantly improved outcomes in men suffering from CP/CPPS," said J. Curtis Nickel, M.D., urologist at Kingston General Hospital and Professor of Urology at Queen's University in Kingston, Ontario, Canada, and lead author of the study. "Importantly, twice as many men treated with RAPAFLO 4 mg once daily versus placebo reported feeling a moderate to marked improvement in their condition, showing that the statistically significant findings also were clinically meaningful for the patients."

Study Results

In this Phase 2 study with 151 patients, compared with placebo, RAPAFLO(R) at a 4 mg dose significantly decreased the total score on the well-recognized National Institutes of Health Chronic Prostatitis Symptom Ind
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SOURCE Watson Pharmaceuticals, Inc.
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