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Waters and NIBRT Complete Work on World's First UPLC Glycan Database
Date:1/20/2012

MILFORD, Mass., Jan. 20, 2012 /PRNewswire/ -- Waters Corporation (WAT:NYSE) and Ireland's National Institute for Bioprocessing Research and Training (NIBRT) announced today the availability of the world's first database for glycan analysis by UltraPerformance Liquid Chromatography® (UPLC®). Developed by Professor Pauline Rudd's research team at NIBRT, the new GlycoBase 3+ Database is the first-of-its-kind repository of chromatographic retention positions expressed in glucose units for sets of glycan structures associated with a range of biotherapeutics. Now available for purchase, the database will be co-marketed worldwide by Waters and NIBRT. The announcement came during the 15th annual Well-Characterized Biopharmaceuticals (WCBP) Symposium, Jan. 23 – 25 in San Francisco, California.

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The GlycoBase 3+ Database is intended to give biopharmaceutical manufacturers a timely and powerful tool for confirming the structure of various glycosylated proteins. Armed with more rapid and accurate information about glycosylation during the various stages of the manufacturing process, biopharmaceutical manufacturers can gain a greater degree of control over their manufacturing process in line with regulatory guidelines aimed at guaranteeing safe and efficacious biotherapeutics.

Recent advances in chromatographic approaches are leading to better resolution, sensitivity, and speed during the qualitative and quantitative analysis of protein glycosylation. As a proven approach for analyzing biomolecules and the glycan structures attached to them, UPLC is a potent t
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