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Waters Honors University of Minnesota's Joseph Dalluge, Ph.D. and Department of Chemistry Mass Spectrometry Laboratory with Center of Innovation Recognition
Date:10/3/2011

matography/mass spectrometry instrumentation for metabolite profiling, biomarker discovery, and advanced assay development and for the detailed chemical characterization of biological systems as it relates to function.

"As I talk to investigators about the power of UPLC combined with MS you can see the light bulbs go on in their heads," Dalluge said. "What's generated the most interest is the concept of looking at dissimilar biological systems and comparing them to find out how they might be different at the molecular level, what characterizes a disease state versus a non-disease state, the differences between an aging cell versus a young cell, a cell exposed to an inflammation agent versus cells not exposed to inflammation agents."

By taking cell extracts and using the power of UPLC® with its high peak capacity, resolution, and speed of separation and combining it with a powerful MS platform and doing MS, MS/MS, and ion mobility, researchers can uncover fine details about incredibly complex biological systems and find subtle differences with potential biological relevance, Dalluge explained.

"That's what is generating a lot of interest here," Dalluge said.

Waters instruments - Waters ACQUITY® UPLC/TQD and ACQUITY UPLC®/Synapt® G2 - will continue to play a major role in Dalluge's research into metabolite profiling, biomarker discovery, and advanced assay development.

"I am honored to be a part of the Centers of Innovation Program and for what it means to us as we conduct leading-edge research. I regard Waters as more than just an instrument vendor of choice. They are a research partner," said Dalluge.

About Waters Centers of Innovation Program

Waters Centers of Innovation Program
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