FREMONT, Calif., March 11, 2013 /PRNewswire/ -- The Salk Institute and WaferGen Bio-systems, Inc. (OTCBB: WGBS) today announced the formation of a nano-qPCR Core Laboratory under the guidance of Ronald M. Evans , Professor and March of Dimes Chair in Molecular and Developmental Biology at Salk. The lab will utilize WaferGen's SmartChip System as the backbone technology for high-throughput real-time PCR studies. A major focus will be on designing and testing libraries of assays targeting receptors and transcriptional regulators for important functional pathways, thereby interrogating entire regulatory networks in a highly parallel fashion. It is also envisioned that the nano-qPCR Core Lab will be an important resource for the larger Salk community.
Dr. Evans commented: "We have successfully tested WaferGen's SmartChip system in our laboratory in a variety of gene expression experiments. The platform is ideal for follow up studies to ChIP Seq, and for de novo large-scale gene expression studies in precious clinical samples. We made SmartChip System the technology of choice based on its ability to perform qPCR without pre-amplification, while providing the required throughput for measuring a series of longitudinal genomic events in cells. Another attractive feature is SmartChip's flexibility, which allows our scientific questions to dictate the experimental design in a convenient and cost-effective workflow."
Chromatin-immunoprecipitation (ChIP) is a technique whereby genomic regulatory sites bound by a specific factor of interest are enriched through antibody precipitation. ChIP Sequencing utilizes modern NGS technology to provide the nucleotide sequences of these regulatory sites. Downstream studies have historically been conducted by designing qPCR assays targeting these elements and have been restricted to small numbers of analytes du
|SOURCE WaferGen Bio-systems, Inc.|
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