MENLO PARK, CA (PRWEB) February 21, 2017
Vortex Biosciences announced the commercial launch of the VTX-1 Liquid Biopsy System, a fully automated benchtop system for collecting intact circulating tumor cells (CTCs) that are shed by tumors, using microfluidic technology. The VTX-1 is being launched at the Molecular Medicine Tri Conference (Tri-Con) Annual Meeting 2017 (February 19–24 San Francisco).
The VTX-1 utilizes microfluidics to automate the isolation of circulating tumor cells (CTCs) directly from whole blood based on the greater deformability and larger size of the CTCs. Shed by tumors into the circulation, CTCs offer a window into cancer biology. Isolating and characterizing CTCs gives researchers new insight and the potential to transform our understanding of cancer and improve the way cancer is diagnosed and treated.
Capturing CTCs out of blood to enable characterization is not easy. CTCs are relatively scarce, with concentrations as low as 1–10 CTCs/mL of whole blood, against a background of millions of white blood cells and billions of red blood cells. Vortex’s VTX-1 Liquid Biopsy System automates the capture and collection of clinically relevant, unaltered CTCs directly from whole blood for analysis. The Vortex VTX-1 system is a fully automated benchtop system for collecting intact CTCs using microfluidic technology. Unlabeled CTCs in whole blood are trapped in microscale vortices while smaller red and white blood cells pass through. After selective trapping into the microfluidic chambers, CTCs are then released and collected into a variety of containers for downstream analysis.
“We believe the VTX-1 has a number of critical advantages in CTC isolation, including its automated and simple workflow, capacity for unbiased CTC capture and high CTC recovery and the ease with which it can be integrated with downstream assays,” commented Vortex CEO Gene Walther. “Empowering cancer researchers with a rapid, reliable and convenient solution to collect CTCs could advance cancer research and accelerate the development of innovative diagnostics and therapeutics.”
The VTX-1’s innovative approach towards capturing CTCs offers a number of advantages over existing approaches:
The VTX-1 represents the next step in CTC isolation resulting in meaningful advancements in cancer research and diagnosis.
About Vortex Biosciences
Vortex Biosciences is a cancer research and diagnostics company that integrates cancer biology, microfluidic engineering and informatics to develop tools for isolating and characterizing circulating tumor cells. The Vortex VTX-1 instrument received CE Mark and FDA Class 1 registration in 2016 and in 2017 launched in US and Europe. It works by harvesting intact circulating tumor cells from whole blood samples for use in downstream research and clinical applications such as patient stratification in clinical trials, monitoring disease progression and drug treatment effectiveness. With a mission to enable noninvasive diagnosis of cancer and real-time monitoring throughout a patient’s treatment, Vortex is at the forefront of accelerating cancer research and improving patient outcomes. Vortex is a core subsidiary of NetScientific plc, a transatlantic healthcare technology group with an investment strategy focused on sourcing, funding and commercializing technologies that significantly improve the health and well-being of people with chronic diseases. For more information, visit http://www.vortexbiosciences.com.
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