Volcano Announces Activities at TCT 2007: Expanded Role of IVUS in PCI to be De... (t placement and improving patient outcom...)

Volcano Announces Activities at TCT 2007: Expanded Role of IVUS in PCI to be Demonstrated

Date:10/22/2007

t placement and improving patient outcomes. This 3,000 patient IVUS sub-study is part of the Cardiovascular Research Foundation's (CRF) ADAPT-DES study (Assessment of Dual AntiPlatelet Therapy with Drug-Eluting Stents), a prospective, multi-center registry of 11,000 (and up to 15,000) patients with coronary artery disease undergoing stent-assisted percutaneous coronary intervention (PCI) using drug-eluting stents (DES). The study's main objectives are to determine the frequency, timing and correlation (clinical, angiographic and IVUS) of DES thrombosis and the relationship of aspirin and/or clopidogrel hyporesponsiveness, and general platelet reactivity to early and late DES thrombosis.

A number of studies have identified improper stent placement as a leading contributor to DES thrombosis. Dr. Antonio Colombo and his associates, for example, have demonstrated that while stents often appeared to be implanted successfully via angiography, IVUS later detected that certain of the stents that appeared to be implanted successfully via angiography were actually under-expanded or incompletely apposed to the vessel wall. The ADAPT IVUS sub-study is expected to further examine such findings and assess the utility of IVUS in reducing complications and improving patient outcomes. Furthermore, a privately-funded study by the Washington Hospital Center found that, in some cases, a lack of IVUS guidance was an independent and statistically significant predictor of stent thrombosis.

Symposia

Volcano is sponsoring a concurrent breakfast symposium on Wednesday, October 24th at 7:00 AM in Room 149AB titled "CTA Guided PCI with Confirmatory IVUS: A New Interventional Paradigm." This symposium will review how IVUS, fractional flow reserve (FFR) and computed tomographic angiography (CTA) can work together to better triage patients for appropriate therapy.

Exhibition Hall Hands-On Demonstrations in Multiple Partner Booths

Volcano's IVUS consoles will be funct
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Volcano Announces Activities at TCT 2007: Expanded Role of IVUS in PCI to be De...(t placement and improving patient outcom...)