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VisionGate Uses $2.6 Million NIH Grant to Achieve Full Automation of Cell-CT™ 3D Imaging System for Early Diagnosis of Cancer
Date:1/6/2012

sion of our first applications to the Food and Drug Administration (FDA) later this year for regulatory review of LuCED."

In a July 2011 presentation at the International Academy for the Study of Lung Cancer's 14th World Conference on Lung Cancer, VisionGate showed how LuCED and the Cell-CT platform can accurately detect cancer cells in sputum samples from individuals at high risk of lung cancer.

Scarlett Spring, President of VisionGate, noted, "Achieving full automation of the Cell-CT platform is another on-time milestone in our plans to file for regulatory approval of the LuCED test during 2012.  It also complements our recently announced strategic partnerships for clinical assessment of the LuCED technology used adjunctively to reduce the high rate of false positive cases that result from x-ray CT lung cancer screening.  We expect these partnerships will provide valuable data to further advance our LuCED regulatory strategy."

LuCED and the Cell-CT platform produce detailed 3D images of cells in sputum, which the system automatically analyzes to identify key features, or biosignatures, associated with potential malignancy.  The analysis yields a score that indicates whether or not cancer cells are present.  The Cell-CT system produces strikingly clear and comprehensive 3D images of the cells, enabling extremely accurate classifications.  LuCED is initially being developed for use in conjunction with x-ray CT screening, which has been shown to reduce lung cancer deaths in high-risk individuals, but which also has a high rate of false positive results.  LuCED is expected to greatly reduce the incidence of false positives, potentially enabling the approach to be used for cost-effective lung cancer screening on a mass scale.

"The Cell-CT 3D imaging system could be a valuable tool for early detection of lung cancer, when the disease is potentially curable," said David Yankelevitz, MD, Professor of Radiology a
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SOURCE VisionGate, Inc.
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