Navigation Links
Virtual nanoscopy: Like 'Google Earth' for cell biologists
Date:8/6/2012

Just as users of Google Earth can zoom in from space to a view of their own backyard, researchers can now navigate biological tissues from a whole embryo down to its subcellular structures thanks to recent advances in electron microscopy and image processing, as described in The Journal of Cell Biology (JCB). An upgrade to the JCB DataViewer (http://jcb-dataviewer.rupress.org), JCB's browser-based image presentation tool, now also makes these data publicly accessible for exploration and discovery.

Since the early days of cell biology, electron microscopy has revealed cellular structures in exquisite detail. The technique has always been limited, however, by the fact that it can only capture a tiny portion of the cell in a single image at high resolution, making it difficult for researchers to relate the structures they see to the cell as a whole, let alone to the tissue or organ in which the cell is located. Viewing samples at lower resolution, on the other hand, can reveal the larger picture of a cell or tissue, but researchers then lose the benefit of seeing fine details.

A team of scientists from Leiden University Medical Center in the Netherlands has addressed this problem by developing new tools for stitching together thousands of electron microscopy images into single, high-resolution images of biological tissuesa "Google Earth" for cell biologistswhich can be explored using the newly enhanced JCB DataViewer.

Faas et al. describe their recent advances to a technique called "virtual nanoscopy" in the August 6th issue of JCB. The researchers were able to stitch together over 26,000 individual images to generate an almost complete electron micrograph of a zebrafish embryo encompassing 281 gigapixels in total at a resolution of 16 million pixels per inch. Using the JCB DataViewer, anyone can navigate the zebrafish image f
'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Spherix to Present at the LHA Life Sciences & Medical Technologies Virtual Conference on February 16
2. Fundamental steps needed now in global redesign of Earth system governance
3. Scholars call for global governance overhaul to ensure Earths sustainability
4. Penn and Brown researchers demonstrate earthquake friction effect at the nanoscale
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virtual nanoscopy: Like 'Google Earth' for cell biologists
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA theory ... of these latent viruses is the Epstein Barr Virus (EBV), ... arthritis (RA) is a chronic inflammatory disease that destroys the ... that RA patients have high concentrations of EBV DNA in ...
(Date:1/15/2014)... 15, 2014 AudioNotch is the internet's ... for the treatment of tinnitus. Patients listen to sound ... over a period of weeks to months, their tinnitus volume ... two forms: Notched Music and Notched White Noise. Now, AudioNotch ...
(Date:1/14/2014)... CA (PRWEB) January 14, 2014 Histogen, ... the products of cells grown under simulated embryonic conditions, ... license agreement with Suneva Medical, Inc. for physician-dispensed aesthetic ... , This agreement is an amendment to ...
(Date:1/14/2014)... 14, 2014 The largest international professional organization ... and therapeutic derivatives thereof has endorsed an educational ... about the challenges of adulterated herb and botanical ... The Society for Medicinal Plant and ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8
... Calif., May 11 Apex Bioventures Acquisition Corporation (NYSE ... that it has received notice from NYSE Amex LLC ... the Company has been accepted by the Exchange and ... 11, 2009 to regain compliance with the continued listing ...
... deCODE genetics,(Nasdaq: DCGN ) today announced its ... A conference call to discuss these results and,recent developments ... May 12, at 8:00am Eastern Daylight Time/12 noon GMT/1pm ... Net loss for the quarter ended March 31, 2009 ...
... May 11 Idenix Pharmaceuticals, Inc. (Nasdaq: IDIX ... overview at the upcoming Deutsche Bank 2009 Health Care Conference ... the Intercontinental Hotel, Boston.The live and archived webcast of the ... the Idenix Investor Center at www.idenix.com . ...
Cached Biology Technology:Apex Bioventures Acquisition Corporation Receives Notice of Extension from NYSE Amex 2deCODE genetics Announces First Quarter 2009 Financial Results 2deCODE genetics Announces First Quarter 2009 Financial Results 3deCODE genetics Announces First Quarter 2009 Financial Results 4deCODE genetics Announces First Quarter 2009 Financial Results 5deCODE genetics Announces First Quarter 2009 Financial Results 6deCODE genetics Announces First Quarter 2009 Financial Results 7deCODE genetics Announces First Quarter 2009 Financial Results 8
(Date:4/22/2014)... team of Yale researchers will lead a five-year, $3 ... rain events is affecting the transport of dissolved organic ... they say could alter the chemical composition and water ... With funding from the National Science Foundation,s MacroSystems Biology ... across the watershed, which begins in Canada and runs ...
(Date:4/22/2014)... RIVERSIDE, Calif. Inspired by the fist-like club ... by University of California, Riverside, in collaboration with University ... design structure for composite materials that is more impact ... , "The more we study the club of this ... improve so many things we use every day," said ...
(Date:4/22/2014)... American Societies for Experimental Biology (FASEB) has released ... how funding from the National Institutes of Health (NIH) ... Rico. "FASEB is pleased to make these factsheets available ... NIH to their state," said FASEB President, Margaret K. ... for biomedical research funding, investing $29.2 billion in ...
Breaking Biology News(10 mins):Connecticut River watershed study will assess impacts of extreme rain events 2Connecticut River watershed study will assess impacts of extreme rain events 3Mantis shrimp stronger than airplanes 2Mantis shrimp stronger than airplanes 3
... role of the Dicer. MicroRNAs are emerging as ... an RNaseIII enzyme, plays a role in the biogenesis ... activity to determine the developmental role of DICER by ... p. 696 of this issue, Maatouk et al. add ...
... new insight into how the cell,s vast array of ... lethally malfunctioning molecules without a system for proteins to ... Just as eyeglasses improve vision, a coat provides warmth ... set of proteins called ubiquitin-like proteins (UBLs) as accessories ...
... after being exposed to a specialized electrical field is ... a stage of cancer already invading other parts of ... process and found cells that expanded the most were ... spread beyond its point of origin. The technique allows ...
Cached Biology News:October 2008 Biology of Reproduction highlights 2St. Jude study gives new insights into how cells accessorize their proteins 2St. Jude study gives new insights into how cells accessorize their proteins 3Expanding cell girth indicates seriousness of breast cancer 2