Navigation Links
Virtual nanoscopy: Like 'Google Earth' for cell biologists
Date:8/6/2012

Just as users of Google Earth can zoom in from space to a view of their own backyard, researchers can now navigate biological tissues from a whole embryo down to its subcellular structures thanks to recent advances in electron microscopy and image processing, as described in The Journal of Cell Biology (JCB). An upgrade to the JCB DataViewer (http://jcb-dataviewer.rupress.org), JCB's browser-based image presentation tool, now also makes these data publicly accessible for exploration and discovery.

Since the early days of cell biology, electron microscopy has revealed cellular structures in exquisite detail. The technique has always been limited, however, by the fact that it can only capture a tiny portion of the cell in a single image at high resolution, making it difficult for researchers to relate the structures they see to the cell as a whole, let alone to the tissue or organ in which the cell is located. Viewing samples at lower resolution, on the other hand, can reveal the larger picture of a cell or tissue, but researchers then lose the benefit of seeing fine details.

A team of scientists from Leiden University Medical Center in the Netherlands has addressed this problem by developing new tools for stitching together thousands of electron microscopy images into single, high-resolution images of biological tissuesa "Google Earth" for cell biologistswhich can be explored using the newly enhanced JCB DataViewer.

Faas et al. describe their recent advances to a technique called "virtual nanoscopy" in the August 6th issue of JCB. The researchers were able to stitch together over 26,000 individual images to generate an almost complete electron micrograph of a zebrafish embryo encompassing 281 gigapixels in total at a resolution of 16 million pixels per inch. Using the JCB DataViewer, anyone can navigate the zebrafish image f
'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Spherix to Present at the LHA Life Sciences & Medical Technologies Virtual Conference on February 16
2. Fundamental steps needed now in global redesign of Earth system governance
3. Scholars call for global governance overhaul to ensure Earths sustainability
4. Penn and Brown researchers demonstrate earthquake friction effect at the nanoscale
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virtual nanoscopy: Like 'Google Earth' for cell biologists
(Date:8/31/2014)... 2014 2014 Market Research ... professional and in-depth research report on the ... information, including Polyacrylamide definition, classification, application, and ... overview. This research covers the international market ... global industry analysis covering macroeconomic environment & ...
(Date:8/29/2014)... based on electrons, but one of the most promising ... circuits based on light (photons) instead of electrons. First, ... stream of single photons and control their direction. Researchers ... to achieve this control, but now scientists at the ... stream of photons emitted one at a time and ...
(Date:8/29/2014)... Aug. 29, 2014 /PRNewswire/ - iCo Therapeutics ("iCo" ... reported financial results for the six months ended ... expressed in Canadian dollars and presented under International ... 2014 Highlights , Announced top-line results ... primary endpoint for subjects enrolled in the Phase ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 A major ... the biotech start-up dense realm of Boston-Cambridge, is gaining ... able investors. James Sherley, the Director of Boston’s Adult ... the local and national visibility of his company an ... 2013. , In addition to a social media marketing ...
Breaking Biology Technology:International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 2International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 3Breakthrough in light sources for new quantum technology 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 3iCo Therapeutics Announces Second Quarter 2014 Financial Results 4The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4
... , , , , , , ... , 1691112, 100 g, ... Inserts/Product , Instructions , , German , ... version - 54 K , , US Material Safety , Data Sheets, ...
... , , , Template , ... outcome of the PCR. For instance, , large amounts of RNA ... of the PCR. Also, impure templates may contain polymerase inhibitors that , ... always use a purification product specifically designed to purify DNA such , ...
... , , , PCR principles , , ... , , Setting up the , ... , , Thermal , Cycling ... Enzymes , Choice of RT-PCR Enzymes , , ...
Cached Biology Technology:PCR reaction components 2PCR reaction components 3PCR reaction components 4PCR reaction components 5PCR reaction components 6Roche Diagnostics Corporation 2
(Date:9/2/2014)... In the battle between our immune systems and ... bacteria-killing viruses known as phages. In a new study, ... Health, Haiti,s National Public Health Laboratory, and elsewhere, report ... their virulence in order to survive. Importantly, the study ... cholera,s mutational escape from phage predation occurs during human ...
(Date:9/2/2014)... the truth; everyone has a tipping point. We all want ... the benefit is great enough. Now, scientists have confirmed the ... , The result was published online this week in ... be honest, even if lying is beneficial," said Lusha Zhu, ... Virginia Tech Carilion Research Institute , where she works ...
(Date:9/2/2014)... Sam Kean stops by Reactions this week to debunk ... that, despite what "Shark Week" may lead you to ... http://youtu.be/KhFygIoW_MA . , Kean,s book, "The Disappearing Spoon: ... History of the World from the Periodic Table of ... 10-episode video series produced for the newly launched American ...
Breaking Biology News(10 mins):War between bacteria and phages benefits humans 2War between bacteria and phages benefits humans 3Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 2Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 3Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 4
... Single person submersibles have been called in to help ... that may hold vital clues to the history of life ... environmental geochemist in the Faculty of Science, says the objects ... microbialites because they are covered with microbes. Some of these ...
... risks from the use of nanomaterials will be explored ... project supported by a $400,000 grant from the U.S.Department ... Nanomaterials are becoming more prevalent in our lives each ... less than one one-thousandth the width of a human ...
... Canadell from CSIRO and the Global Carbon Project, and ... of tons of carbon dioxide (CO2) absorbed annually by ... change mitigation worth hundreds of billions of dollars. ... challenges in quantifying changes in the size of those ...
Cached Biology News:Mini subs to probe odd structures in BC lake 2Growing use of nanomaterials spurs research to investigate possible downsides 2Growing use of nanomaterials spurs research to investigate possible downsides 3Tropical forest sustainability: A climate change boon 2
... ,Schistosomal glutathione-S-transferase (GST) is commonly ... proteins in E. coli (1). The GSTTag ... production and in some cases the solubility ... a soluble, properly folded form, GSTTag fusion ...
... peptide whose sequence is from the C-terminal end of the mouse retinoic ... amino acids 429 to 448 of RAR*. The sequence of PEP-005 ... - S - P - S - S - V - E ... - S - P - L - L - Q (The ...
... applications for the use of small interfering ... via the RNA interference (RNAi) pathway have ... molecular biology fields. siRNA for experimental use ... or enzymatically, and then transfected into the ...
... The HybArray 12™ is an automated ... microarrays. The system automates both the hybridization ... onto glass slides. A single instrument can ... time in pairs and has multi-protocol software, ...
Biology Products: