Navigation Links
Viron reports positive proof of concept results in arthritis for its VT-346 anti-TNF therapeutic
Date:3/16/2010

LONDON, ON, March 16 /PRNewswire/ - Viron Therapeutics Inc. announced that VT-346, an anti-TNF protein therapeutic, demonstrated positive results in a pivotal proof of concept study in the gold standard transgenic mouse model for arthritis. VT-346 achieved a statistically significant, dose dependent impact in this preclinical model of arthritis and prevented deterioration due to disease in terms of weight gain, arthritic score and pathology parameters. VT-346 had particularly strong protective effects on therapeutically-important bone and cartilage damage in this model. The target for VT-346 is the inflammatory cytokine TNF, which is also the target for several biological therapies whose annual sales are expected to top $20 billion in 2010, making anti-TNF therapies the most commercially successful single-target group of biological therapies. Notable, however, is VT-346's unique method of neutralizing TNF, an important mediator of inflammation and therapeutic target in diseases including rheumatoid arthritis, Alzheimer's disease and Crohn's disease.

"The development of an anti-TNF therapy that is fundamentally different from existing therapies offers hope to patients that do not respond adequately to existing anti-TNF drugs," said Dr. Edward Keystone, Head of the Rebecca MacDonald Centre for Arthritis and Autoimmune Diseases and a recognized leader in the development of drugs targeting rheumatoid arthritis. "Approximately 30-50% of patients do not respond optimally to currently available anti-TNF therapies. The potency in pre-clinical studies and unique mechanism by which VT-346 functions could allow clinicians to achie
'/>"/>

SOURCE Viron Therapeutics Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Sigma-Aldrich and Lab Manager Magazine Present Webinar On Laboratory Environmental, Health and Safety Compliance Strategies
2. Landfill mining reduces environmental impact of growing waste
3. Landfill mining reduces environmental impact of growing waste
4. Nanowire generates power by harvesting energy from the environment
5. Caliper Life Sciences Awarded National Institute of Environmental Health Services Contract Valued to $7.0 Million
6. Environmental Tectonics Corporations BioMedical Division Announces New Contract
7. Sinovac Reports Top-Line Preliminary Phase II Results of Pandemic Influenza (H5N1) Whole Viron Vaccine
8. Environmental Tectonics Corporation Announces Sale of Monoplace Hyperbaric Chambers
9. NanoLogixs Hydrogen-From-Waste Technology at Welchs Foods Featured on Environmental Radio Program
10. Nanotechs health, environmental impacts worry scientists and the public
11. Fixed C-Arms Revolutionize Operating Room Environments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... The report expects global cell isolation ... It also provides a carefully analyzed data about the ... the market. , Full Copy of Report @ ... market for cell expansion will keep witnessing growth at ... growth to be driven by rapid technological advancements, government ...
(Date:12/24/2014)... 23, 2014 China Biologic Products, Inc. ... leading fully integrated plasma-based biopharmaceutical company in ... majority-owned subsidiary, Shandong Taibang Biological Products Co. Ltd., ... the China Food and Drug Administration (the "CFDA") ... previously disclosed in the Company,s public filings, the ...
(Date:12/24/2014)... 2014 PharmaBoardroom,s new report, ... and available for free download , digs deep into ... growth in the sector today. One area where ... been in developing a homegrown pharmaceutical manufacturing base, even if ... remains some way off. A cursory comparison with neighboring ...
(Date:12/24/2014)... 23, 2014  Rock Creek Pharmaceuticals, Inc., (NASDAQ: ... a Clinical Trial Application (CTA) with the ... (MHRA) seeking regulatory approval to initiate clinical trials for ... Contingent on the Company receiving CTA regulatory ... trial to assess the safety, tolerability and dose escalation ...
Breaking Biology Technology:The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3
... Inc. (Nasdaq: NBIX ) today announced its financial results ... For the fourth quarter of 2010, the Company reported net ... a net loss of $7.9 million, or $0.20 per basic share, ... 31, 2010, the Company reported a net loss of $8.0 million, ...
... ROCKVILLE, Md., Feb. 10, 2011 Novavax, Inc. (Nasdaq: ... today that Dr. Rahul Singhvi, President and Chief Executive ... Annual BIO CEO & Investor Conference on February 15th, ... Biotechnology Industry Organization (BIO), the 13th Annual BIO CEO ...
... nanoparticles and graphene results in a more durable catalytic material ... the Journal of the American Chemical Society. The catalytic material ... The researchers are confident the results will help improve fuel ... energy technology, but cost and durability are big challenges," said ...
Cached Biology Technology:Neurocrine Biosciences Reports Fourth Quarter and Year End 2010 Results 2Neurocrine Biosciences Reports Fourth Quarter and Year End 2010 Results 3Neurocrine Biosciences Reports Fourth Quarter and Year End 2010 Results 4Neurocrine Biosciences Reports Fourth Quarter and Year End 2010 Results 5Neurocrine Biosciences Reports Fourth Quarter and Year End 2010 Results 6Neurocrine Biosciences Reports Fourth Quarter and Year End 2010 Results 7A paperweight for platinum 2A paperweight for platinum 3
(Date:12/22/2014)... , Dec. 22, 2014  The 2014 Holiday ... biometrics industry as Acuity Market Intelligence reports that ... finally be open. Acuity forecasts that intensifying demand ... that incorporate biometrics will drive a global market ... biometric devices by 2020.   According ...
(Date:12/17/2014)... 2014 Research and Markets ( ... "Samsung Galaxy S5 - Home Button Synaptics ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... technology than the iPhone 5S, Samsung introduces for ... product. The Galaxy S5 home button ...
(Date:12/17/2014)... Dec. 16, 2014  Automation is fundamentally transforming ... evident than at international borders. Over the past ... have allowed veteran travelers to self process through ... (APC) Kiosks at an increasing number of airports, ... According to Maxine Most , ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... 10, 2009)Interventional radiologists are fitting together the puzzle pieces ... or more blood vessels to treat peripheral arterial disease ... arteries. That puzzle may be closer to being solved ... imaging to view and locate transplanted stem cells and ...
... DIEGO, Calif. (March 10, 2009)The use of common and ... with traditional risk scoring systemssuch as the Framingham Risk ... thousands of individuals who are not originally thought to ... researchers at the Society of Interventional Radiology,s 34th Annual ...
... Jim Pathman Oversees Software Development, Operations, Information Technology ... Analytics, Inc., the leader in on-demand identity intelligence, ... company as its chief information officer. Pathman is ... 20-year track record of using leading edge technology ...
Cached Biology News:'Seeing' stem cells helps in fight against peripheral arterial disease 2'Seeing' stem cells helps in fight against peripheral arterial disease 3'Seeing' stem cells helps in fight against peripheral arterial disease 4Simple test helps predict heart attack risk 2Simple test helps predict heart attack risk 3ID Analytics Appoints Chief Information Officer 2
CD69/CD3 50 tests...
Mouse monoclonal [CIG 3A11/5] to Cig2 (rating: *****) ( Abpromise for all tested applications)....
Goat polyclonal to Glucose Dehydrogenase ( Abpromise for all tested applications). Antigen: Glucose Dehydrogenase (Bacillus species)...
Request Info...
Biology Products: