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Virobay Appoints David B. Karpf, M.D. as Chief Medicial Officer
Date:11/3/2011

Karpf joins Virobay from Metabolex, where he served as chief medical officer and vice president, clinical affairs. While at Metabolex, Dr. Karpf oversaw the development of four clinical programs spanning type 2 diabetes, dyslipidemia, and gout, including 2 INDs, 7 Phase 1 trials and 6 Phase 2 trials.  Prior to Metabolex, Dr. Karpf was executive director of clinical research and regulatory affairs at Geron where he provided oversight for Geron's early clinical programs in cancer and regenerative medicine.  Prior to Geron, Dr. Karpf was vice president, clinical and regulatory affairs at Calydon, Inc.  Prior to his tenure at Calydon, Dr. Karpf was executive director of clinical research at Roche Global Development in Palo Alto and was responsible for clinical development activities in metabolic bone disease and endocrinology, including managing the Phase 3 pivotal program for Boniva™.  Dr. Karpf was previously director of clinical research at Merck Research Laboratories in Rahway, New Jersey.  During his time at Merck he designed, monitored, and completed Phase 2, 3 and 4 clinical trials on Fosamax™ and played a pivotal role in the successful NDA and launch of this product.  In addition to his industry experience, Dr. Karpf has held several academic positions and is currently an adjunct clinical professor of endocrinology with the Stanford University School of Medicine, where he directs one of the endocrine subspecialty clinics.  He received his M.D. degree from University of California, San Diego, served on the fulltime endocrine faculty at UCSF School of Medicine, and has published numerous scientific papers and abstracts in the fields of endocrinology, bone disease, dyslipidemia and cancer.

About Virobay

Virobay is a leader in the design, synthesis and development of small molecule inhibitors of cysteine proteases, a diverse class of enzyme proteases that are key mediators in a variety of diseases,
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