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Virginia Commonwealth University to Study Genomics-Based Diagnostic Test: Pathwork Diagnostics' Tissue of Origin Test Designed to Aid in Determination of a Tumor's Origin
Date:11/6/2007

er to ensure that our cancer patients continue to receive the best possible care."

The Pathwork Tissue of Origin Test's proprietary analytics are designed to measure the expression of more than 1600 genes and compare a tumor's genetic "signature" against those of 15 known tissue types. The test uses microarray technology, which enables large numbers of genes to be evaluated at the same time, using the proven, commercially available Affymetrix instrument system. Up until now, microarrays have been used primarily as research tools but presented challenges for use in clinical settings.

"Our unique processes have enabled us to overcome the challenges of applying microarray technology for clinical use and develop clinically useful diagnostic tests using microarray-based data," explained Pathwork President and C.E.O. Deborah J. Neff. "The microarray is a great platform because we can look at so many pieces of information simultaneously."

Note: The Pathwork Tissue of Origin Test is not cleared by the FDA for sale in the U.S. It is for Investigational Use Only.

Association for Molecular Pathology (AMP) Annual Meeting

At this week's 12th Annual Meeting of the Association for Molecular Pathology, Pathwork Diagnostics will host a corporate workshop, "Diagnostic System to Identify the Tissue of Origin in Poorly Differentiated or Undifferentiated Cancers Using Gene Expression," presented by Federico Monzon, M.D., Methodist Hospital, Houston, TX; and Iris Schrijver, M.D., Stanford University, Stanford, CA (Wednesday, November 7, 4-5 PM, Santa Monica Room).

A second Pathwork Diagnostics workshop, "Designing for IVDMIA, Gene Expression Profiling and Molecular Oncology," will take place as part of the Affymetrix Corporate Workshop. It will be presented by C. Ted Rigl, Ph.D., V.P. Product Development at Pathwork Diagnostics (Wednesday, November 7, 10 AM to noon, Olympic A Room).

The Tissue of Origin Test is the focus of two poster presentatio
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SOURCE Pathwork Diagnostics
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