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Video: Higher Initial Dose of Gleevec Achieved Better Early Responses than Standard Dose for Patients with Chronic Myeloid Leukemia
Date:6/13/2008

and net income of USD 6.5 billion. Approximately USD 6.4 billion was invested in R&D activities throughout the Group. Headquartered in Basel, Switzerland, Novartis Group companies employ approximately 98,200 full-time associates and operate in over 140 countries around the world. For more information, please visit http://www.novartis.com.

For more information

Additional information regarding Gleevec, Tasigna and Novartis Oncology can be found on the websites http://www.novartisoncologyvpo.com, http://www.gleevec.com, http://www.us.tasigna.com and http://www.novartisoncology.us.

References

1. Cortes J. First report of the TOPS study: A randomized phase III trial

of 400mg vs 800mg imatinib in patients with newly diagnosed, previously

untreated CML in chronic phase using molecular endpoints. Abstract.

13th Congress of the European Hematology Association, Bella Center,

Copenhagen, Denmark, June 12-15, 2008.

2. Larson, R., Druker, B. et al. Imatinib pharmacokinetics and its

correlation with response and safety in chronic phase chronic myeloid

leukemia: a subanalysis of the IRIS study. Blood, Feb 2008.

3. Gleevec(R) (imatinib mesylate) tablets prescribing information. East

Hanover, NJ: Novartis Pharmaceuticals Corporation; Nov 2007.

Media Contacts

Media Only:

Kim Fox

Novartis Oncology

P: +1 862 778 7692

C: +1 917 415 2425

Dana Kahn Cooper

P: +1 732 817 1800

C: +1 732 239 6664

Investors only:

Jill Pozarek

Novartis Corporation

P: +1 212 830 2445


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