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About Cancer Cachexia and VT-122
Cancer cachexia results in severe wasting of muscle and connective tissue and is one of the most common debilitating and distressing conditions of advanced cancer. Severe cachexia is associated with extreme weakness, intolerance to chemotherapy and substantially reduced life expectancy. There is currently no FDA-approved therapy for cancer cachexia.
VT-122 targets inflammatory and other key pathways thought to be responsible for the onset and observed clinical symptoms of cancer cachexia. The use of VT-122 is currently being evaluated under a U.S. IND in a Phase 2 study being conducted concurrently at multiple sites in the U.S. and India. Results from the ongoing trial are expected by end of 2007.
About Vicus Therapeutics
Vicus Therapeutics is a privately-held, biopharmaceutical company
focused on the development of pharmaceutical product candidates for the
treatment of cancer supportive care indications with an initial focus on
cachexia. Vicus' strategy involves combining individual generic drugs that
have previously received regulatory approval for other indications and thus
have established post-marketing safety records. Vicus leverages its
proprietary science to design and patent novel drug combinations that work
together to reverse the body's maladaptive responses to cancer and its
treatment. Vicus' lead combination product candidate, VT-122, is in Phase 2
clinical trials for the treatment of cancer cachexia in patients with
advanced lung cancer. Additionally, Vicus has preclinical-stage combination
product candidates being evaluated for the treatment of oral mucositis and
cancer fatigue. Vicus' development programs are powered by its network of
leading clinical investigators and partners in the US, India and Japan.
This international network drives the high quality, rapid and cost
effective clinical devel
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SOURCE Vicus Therapeutics![]() Copyright©2007 PR Newswire. |