Date:4/23/2008

rights to data from Bayer-Schering or the potential failure of Zevalin to be approved by the FDA for first-line treatment of non-Hodgkin's lymphoma, the failure of XYOTAX, pixantrone or brostallicin to prove safe and effective for their intended uses, a determination by the EMEA that XYOTAX should not be approved for sale in Europe, other determinations by regulatory, patent and administrative governmental authorities, competitive factors, technological developments, costs of developing, producing and selling Zevalin, XYOTAX, pixantrone and brostallicin, the risk that Novartis may not elect to participate in the development and marketing of XYOTAX or may not exercise its option with regard to pixantrone, the risk that Mr. Phillips may not join CTI as President on August 1, 2008 or remain with the Company, and the risk factors listed or described from time to time in the Company's filings with the Securities and Exchange Commission including, without limitation, the Company's most recent filings on Forms 10-K, 8-K, and 10-Q. Except as may be required by Italian law, CTI is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements whether as a result of new information, future events, or otherwise.

Media Contact:

Dan Eramian

T: 206.272.4343

C: 206.854.1200

Lindsey Jesch

T: 206.272.4347

F: 206.272.4434

E: media@ctiseattle.com

http://www.celltherapeutics.com/media.htm

Investors Contact:

Leah Grant

T: 206.282.7100

F: 206.272.4434

E: invest@ctiseattle.com

http://www.celltherapeutics.com/investors.htm

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SOURCE Cell Therapeutics, Inc. Copyright©2008 PR Newswire. All rights reserved

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