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Very Small Embryonic-Like Stem Cell Mobilization Data Presented at International Society for Stem Cell Research Annual Meeting
Date:6/17/2010

ion of very small embryonic-like stem cells from the bone marrow to peripheral blood, will be presented in a poster session on June 17.

The poster is entitled "Mobilization and Isolation of Human Very Small Embryonic-Like Stem Cells (VSELs) from Peripheral Blood". Authors of the abstract included:

Dr. Mariusz Ratajczak, M.D., Ph.D., Director of the Stem Cell Biology Program at University of Louisville, which partners with NeoStem to develop technologies, based on NeoStem's exclusive license, to identify and isolate rare adult stem cells called very small embryonic-like stem cells;

Dr. Wayne A. Marasco, M.D., Ph.D., Associate Professor at the Dana-Farber Cancer Institute and Associate Professor of Medicine at Harvard Medical School, and Chairman of NeoStem's Scientific Advisory Board;

Denis O. Rodgerson, Ph.D., MSC, Director of Stem Cell Science at NeoStem.

Satish Medicetty, Ph.D., formerly Director of Stem Cell Research & Laboratory Operations at NeoStem.

The abstract shows that very small embryonic-like stem cells, normally rare in peripheral blood, can be released in greater numbers from the bone marrow by using an FDA approved drug called G-CSF. They can then be collected by a process called apheresis, a process used as standard-of-care in blood donations. The authors postulate that G-CSF mobilization could become a novel strategy to obtain human pluripotent stem cells, which are stem cells that have the potential to regenerate all the cell types of the body. In this poster, the authors have presented data taken from 28 human donors that demonstrate the significant
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SOURCE NeoStem, Inc.
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