Navigation Links
Vermillion and Collaborators Discover Protein Biomarker Associated with Peripheral Artery Disease
Date:8/28/2007

ary angiography. Proteomic profiling studies of the blood revealed a protein that was higher in patients with PAD. In subsequent studies, the protein was identified as beta-2 microglobulin.

Beta-2 microglobulin levels were correlated with the severity of disease, as determined by ankle blood pressures, and by the distance patients could walk on a treadmill. Beta 2microglobulin was an independent predictor, even after taking into consideration traditional risk factors such as cholesterol, diabetes, and age.

"This biomarker discovery may provide new insight into the pathophysiology of peripheral artery disease and may contribute towards the development of our panel of biomarkers to identify patients at risk for PAD," said Eric T. Fung, M.D., Ph.D., Chief Scientific Officer for Vermillion. "We are engaged in final validation studies to determine an optimal cutoff that stratifies patients according to their likelihood of having peripheral artery disease."

As part of a strategic alliance agreement, Vermillion and Quest Diagnostics are working closely together to expedite development and release of the PAD test.

About Peripheral Artery Disease (PAD)

PAD, a serious but often asymptomatic disorder affecting some eight to 12 million Americans, is caused by the buildup of fat and cholesterol, or plaque, in the peripheral arteries, disrupting normal blood flow. Left untreated, PAD more than doubles the risk of heart attack and stroke and increases the risk of amputation and death. There are treatments that can save the lives and limbs of these patients, once the disease is recognized.

About Vermillion's Peripheral Artery Disease Program

Vermillion, in collaboration with Stanford University, is developing a blood-based assay for the detection of PAD. In January 2007, Quest Diagnostics accepted this program as the second of three diagnostic tests for joint development under their existing strategic alliance agreement.

About Vermill
'/>"/>

SOURCE Vermillion, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Stratagenes Human cDNA Microarrays: Perform Gene Expression Profiling and Discover New Genes
2. SEESNP DISCOVERY
3. siRNA screening of the cell cycle with two dynamic GFP sensors (from Discovery Matters Issue 1, July 2005)
4. Exploiting the Life Science Data Explosion to Speed New Drug Discovery
5. Rapid, High Throughput Mutation Discovery Using Fluorescent SSCP on the ABI PRISM 3100 and 3100Avant Genetic Analyzers
6. Quantitation of Acrylamide in Food Samples on the Finnigan TSQ Quantum Discovery by LC/APCI-MS/MS
7. Increased Analyte Sensitivity through the Utility of Enhanced Mass-Resolution on the FinniganTSQ Quantum Discovery
8. A new wide field-of-view confocal imaging system and its applications in drug discovery and pathology
9. Document retention policy can get your arms around eDiscovery
10. Finding Safe Harbor in a sea of electronic discovery
11. Quick peeks, Clawback Agreements, and the rules of electronic discovery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... rather than electricity, to move data would consume ... a growing concern as chips, transistor counts rise. ... circuits light emitters, modulators, and detectors ... light source for optical chips is molybdenum disulfide ... as a single, atom-thick layer. Other experimental on-chip ...
(Date:9/19/2014)... , September 19, 2014 ... technology, development of emerging drug systems and advanced Laboratory ... Dickinson and Company (NYSE: BDX ), Thermo ... Biosciences Inc. (NASDAQ: RGDO ), Sangamo Biosciences ... (NASDAQ: HOLX) Pressure BioSciences, Inc. (OTCQB: PBIO) ...
(Date:9/19/2014)... CORAL SPRINGS, Florida , September 19, 2014 /PRNewswire/ ... biotech companies release latest developments, patents and results of ... (OTC: GNSZ), Eli Lilly and Company (NYSE: ... ), Celgene Corporation (NASDAQ: CELG ) and ... (OTCQB: GNSZ), a leader in developing prodrug therapeutics for ...
(Date:9/19/2014)... , September 19, 2014 ... and Markets ( http://www.researchandmarkets.com/research/b2jxhs/micro_market ) has announced the addition ... Chromatography Columns"  report to their offering.  ... market is one of the fastest-growing segments in ... $1.2 billion in 2013, and expected to reach ...
Breaking Biology Technology:Toward optical chips 2Toward optical chips 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 2Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 4Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 5Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 6Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 7Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7Micro Market Monitor : Global Pre-packed Chromatography Columns 2
... economic,and business growth in the Tampa Bay Region from the ... Acquires Manufacturing Site in Tampa Bay , ... St. Petersburg recently where it plans to manufacture microchips for ... should be completed,in March 2009. The site could employ ...
... PRINCETON, N.J., Jan. 6 Medarex, Inc. (Nasdaq: ... at the 27th Annual J.P. Morgan Healthcare Conference at 8:30 ... 13, 2009. The event will be webcast live and will ... website at www.medarex.com . An archived edition of the ...
... Biosciences, Inc. announced today that David J. Mazzo, Ph.D., ... the 27th Annual J.P. Morgan Healthcare Conference in San ... Pacific Time (2:30pm Eastern Time). Dr. Mazzo,s presentation ... in development, the REG1 System, its pipeline and enterprise-level ...
Cached Biology Technology:Highlights of Economic and Business Growth in the Tampa Bay Region (News Briefs) 2Highlights of Economic and Business Growth in the Tampa Bay Region (News Briefs) 3Highlights of Economic and Business Growth in the Tampa Bay Region (News Briefs) 4Medarex to Present at the 27th Annual J.P. Morgan Healthcare Conference 2
(Date:9/18/2014)... new GSA Bulletin study uses tree rings ... and Chaco Wash in northern New Mexico, USA. By ... and willow, investigators were able to precisely date arroyo ... combined this data with aerial imagery, LiDAR, longitudinal profiles, ... arroyos. , Arroyos are deep, oversized channels that have ...
(Date:9/18/2014)... researchers from McGill University and the Quebec government ... ,microbeads, Canadian Journal of Fisheries and Aquatic ... cosmetics, household cleansers, or industrial cleansers, to which ... their small size and buoyancy, they may readily ... a global contaminant in the world,s oceans, but ...
(Date:9/18/2014)... in DNA, tiny strands of nucleic acid that contain ... this genetic data, our DNA is copied into RNA ... perform tasks in our cells. , Several years ... Unlike all other known RNAs, this molecule is circular, ... abundant, little has been known about how they are ...
Breaking Biology News(10 mins):Tree rings and arroyos 2Tree rings and arroyos 3Tree rings and arroyos 4Tree rings and arroyos 5Tree rings and arroyos 6Tree rings and arroyos 7Microplastic pollution discovered in St. Lawrence River sediments 2Scientists find how mysterious 'circular RNA' is formed, claim muscular dystrophy link 2
... In the last decade, a new strain of MRSA has ... risk of contracting the dangerous bacterial infection. This particular strain ... of genes not shared by any other strains, though it ... to survive and persist in the community. Now, research ...
... The rate of chemical processes in cells is dictated by ... given reaction. Using a versatile method developed at the Institute ... Warsaw, researchers were able to predict for the first time ... . The achievement is important not only for biologists and ...
... the original Otom inhabitants of Xaltocan, the capital of ... long wondered whether they assimilated with the Aztecs or ... research from The University of Texas at Austin, Wichita ... lie in DNA. Following this line of evidence, the ...
Cached Biology News:UNC study may lead to treatments that are effective against all MRSA strains 2Biologistics: How fast do chemical trains move in living cells? 2Biologistics: How fast do chemical trains move in living cells? 3Aztec conquest altered genetics among early Mexico inhabitants, new DNA study shows 2