Navigation Links
Vasogen's Research Published in European Journal of Neuroscience
Date:1/28/2008

- VP025 Provides a Neuroprotective Effect in Preclinical Model of

Parkinson's Disease -

MISSISSAUGA, ON, Jan. 28 /PRNewswire-FirstCall/ - Vasogen Inc. (NASDAQ:VSGN; TSX:VAS), a biotechnology company engaged in the research and commercial development of therapies designed to target the destructive inflammatory process associated with the development and progression of cardiovascular and neurodegenerative disorders, today announced the publication of preclinical findings demonstrating that Vasogen's VP025, the leading candidate from its VP series of drugs, provides a significant neuroprotective effect in a model of Parkinson's disease. The research, which was conducted at the University College Cork, Ireland, was published in the European Journal of Neuroscience (Vol 27, pp.294-300, 2008).

Evidence is accumulating that inflammation plays an important role in the pathogenesis of Parkinson's disease. Microglial cells (immune cells resident in the brain) are activated in Parkinson's disease, producing pro-inflammatory factors that result in the death of nerve cells in an area of the brain called the nigrostriatal pathway. The published research was based on a well-established model of Parkinson's disease that involves the generation of a lesion on one side of the brain by the introduction of 6-hydroxydopamine (6-OHDA), inducing abnormal behaviour resulting in rotational movement. Both Parkinson's disease and 6-OHDA administration are associated with inflammatory processes that lead to the death of certain nerve cells, the dopaminergic neurons, which produce the neurotransmitter dopamine. It is the loss of these neurons and thereby the dopamine they produce that results in the movement abnormalities s
'/>"/>

SOURCE Vasogen Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Researchers Pinpoint Best Treatment to Reduce Deadly USA300, MRSA Staph Infections
2. Researchers develop darkest manmade material
3. Clinimetrics Celebrates 20th Anniversary in Contract Research Business
4. Quintiles to Open Clinical Research Office in Wilmington, NC
5. Irving Dark Named Vice President of Cytel Clinical Research Services
6. Boost for Malaria Vaccine Development by Combining Strengths of Dutch and American Researchers
7. VIA Pharmaceuticals Names Rebecca Taub Senior Vice President of Research and Development
8. Collaborative Biosecurity Research Initiative Launched to Target Animal and Public Health Threats Nationally
9. Premier Research Names Patrick Melvin as Senior Director, Clinical Trial Management
10. Protalix BioTherapeutics Signs Lease Agreement for Expansion of its Manufacturing and Research Facility in Carmiel, Israel
11. A New, Unique and Unrivalled Rat/Mouse PINP Assay for Pharmaceutical, Clinical and Academic Research Organizations.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... Tooth decay is an epidemic in American children with 50% ... World Health Organization says that worldwide, 60–90% of ... are the long-term effects of this transmissible infection? , ... oral bacterial imbalance and serious systemic issues like heart disease. ... also 100% preventable? Answer: there has been no way to ...
(Date:5/16/2013)... (PRWEB) May 16, 2013 A ... portable models, from Cole-Parmer is designed to meet ... line includes: , The new Cole-Parmer® MS-3400 ... workhorses in the lab. They ensure a powerful ... plasma specimen separation. Their standard four-place swinging buckets ...
(Date:5/16/2013)... Scientists at the Center for Learning and ... the California -based biopharmaceutical company Magceutics, ... for reversing memory decline in mice with Alzheimer,s Disease. ... improvement in advanced stage AD mice. The study is ... decline for advanced stage AD mice, and is also ...
(Date:5/16/2013)... 16, 2013 BioInformatics LLC New Market ... Stem Cell-Derived Cells: Current and Future Opportunities (13-004) ... suppliers in the primary cells market continues to increase. ... are used most often, how satisfied scientists are with ... and anticipated growth rate. ,  , Additionally, terminally ...
Breaking Biology Technology:Seeing the Future: How a Revolutionary New Bacterial Screening Device Can Predict a Patient’s Future for Tooth Decay 2Seeing the Future: How a Revolutionary New Bacterial Screening Device Can Predict a Patient’s Future for Tooth Decay 3Cole-Parmer Offers Enhanced Selection of Centrifuges 2Elevation of Brain Magnesium Reverses Memory Deficits in Alzheimer Mice 2Elevation of Brain Magnesium Reverses Memory Deficits in Alzheimer Mice 3BioInformatics LLC New Market Report – The Market for Primary Cells & Stem Cell-Derived Cells: Current and Future Opportunities (13-004) 2BioInformatics LLC New Market Report – The Market for Primary Cells & Stem Cell-Derived Cells: Current and Future Opportunities (13-004) 3
... tea, soda and hot chocolate present risk, ... daily caffeine,during pregnancy -- whether from coffee, tea, ... risk of miscarriage, according a new study,by the ... for,the first time, pregnancy-related symptoms of nausea, vomiting ...
... antiviral activity in patients with ... NNRTI-resistant virus ... and Drug,Administration (FDA) has granted accelerated approval to the anti-HIV,medication ... to show antiviral activity in,treatment- experienced adult patients with HIV ...
... 18 Eli Lilly and Company,strongly objects to implications ... company has suppressed results of negative clinical,trials., The ... England Journal of,Medicine (NEJM), cited Prozac and Lilly as ... trial data. Not only was,the Times, story inaccurate when ...
Cached Biology Technology:Kaiser Permanente Study Shows Newer, Stronger Evidence That Caffeine During Pregnancy Increases Miscarriage Risk 2Kaiser Permanente Study Shows Newer, Stronger Evidence That Caffeine During Pregnancy Increases Miscarriage Risk 3Kaiser Permanente Study Shows Newer, Stronger Evidence That Caffeine During Pregnancy Increases Miscarriage Risk 4FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 2FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 3FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 4FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 5FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 6FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 7FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy 8In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement: 2In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement: 3In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement: 4
(Date:5/18/2013)... today at Digestive Disease Week (DDW) explores new discoveries ... of coffee on autoimmune disease and palliative care for ... been associated with reduced risk of fibrosis, a new ... java each month also correlate with lower risk for ... Clinic, Rochester, MN, linked coffee consumption with reduced risk ...
(Date:5/17/2013)... AGA Research Foundation announced a new grant that intends ... microbiota, one of today,s most exciting areas of science, ... Research Awards Panel selected Andrew T. Chan, MD, MPH ... Medical School, Boston, as the 2013 AGA-Elsevier Gut Microbiome ... of funding, commencing in July 2013, to test the ...
(Date:5/17/2013)... Atlanta residents of all ages will celebrate the ... impact on our daily lives during the inaugural ... engineers and educators from local museums, corporations, K-12 ... than 40 different events for children and adults ... http://atlantasciencefestival.org . , The annual Atlanta ...
Breaking Biology News(10 mins):Coffee consumption associated with reduced risk of autoimmune liver disease 2New gut microbiome research to explore red meat -- colorectal cancer pathway 2First Atlanta Science Festival set for 2014 2
... study led by Boston University School of Public Health ... decongestants during their pregnancies are less likely to give ... than 37 weeks, gestation -- is the leading ... but its causes remain largely unknown, said Rohini Hernandez, ...
... 30 August 2010 The coming weeks mark the return ... satisfaction of making new friends and obtaining good test scores ... some school-aged adolescents. The previous decade has witnessed a two-fold ... 12 to 17. 1,2 In an effort ...
... often take communication courses unrelated to their major or ... up with the Library and English Departments to develop ... understand literature searchers and incorporate them into papers and ... Gail R. Nonnecke, Iowa State University faculty from the ...
Cached Biology News:BUSPH study observes link between decongestant use in pregnant women and lower risk of preterm birth 2School-based intervention successfully lowers drinking rates in at risk children 2Teaching communication and information literacy skills 2
NuParaffin Kit Application: Flow Cytometry Reactivity: Human...
Request Info...
...
Highly efficient electroporation solution suitable for transfection of plasmid DNA, oligonucleotides and siRNA. Compatible with all common electroporators....
Biology Products: