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Valdoxan(R) Granted Marketing Authorisation for the Treatment of Major Depressive Episodes in Europe
Date:2/24/2009

mechanism of action is unlike those of the commonly-prescribed antidepressants, the SSRIs and SNRIs, as Valdoxan exerts its antidepressant efficacy without having an impact on serotonin levels," pointed out Professor Racagni from the University of Milan, Italy.

The recommended dose of Valdoxan is one tablet of 25 mg taken once daily, orally at bedtime.

Following approval from the European Commission, Valdoxan is expected to become commercially available in European countries in the coming months.

Valdoxan(R) was discovered and developed by Servier, France's leading independent pharmaceutical company.

References

(1) Lôo H, Hale A, D'haenen H. Int Clin Psychopharmacol. 2002;17:239-247.

(2) Montgomery SA, Kasper S. Int Clin Psychopharmacol. 2007;22:283-291

(3) Kasper S, Laigle L, Baylé F. Eur Neuropsychopharmacol. 2008;18(suppl4):S336.Abstract P2c022.

(4) Goodwin G, Rouillon F, Emsley R. Eur Neuropsychopharmacol. 2008;18(suppl4):S338. Abstract P2c025.

(5) Lemoine P, Guilleminault C, Alvarez E. J Clin Psychiatry. 2007;68:1723-1732.

(6) Kennedy SH, Rizvi S, Fulton K, Rasmussen J. J Clin Psychopharmacol. 2008;28:329-333.

(7) Montgomery SA, Kennedy SH, Burrows GD, Lejoyeux M, Hindmarch I. Int Clin Psychopharmacol. 2004;19:271-280

(8) Leproult R, Van Ondergergen A, L'Hermite-Balériaux M, Van Cautert E, Copinschi G. Clin Endocrinol. 2005;63:298-304.


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