Navigation Links
Vaccination reduces the risk of unvaccinated badger cubs testing tuberculosis positive

New evidence from a four-year field study has shown that BCG vaccination reduces the risk of tuberculosis infection in unvaccinated badger cubs in vaccinated groups, as well as in badgers that received the vaccine.

The research, published today in the journal PLOS ONE provides the strongest evidence to date that unvaccinated badger cubs can be indirectly protected from TB infection when some of the badgers in their social group are vaccinated. By studying rates of new cases of TB in cubs in vaccinated social groups, researchers have shown that the risk of non-vaccinated cubs testing positive was reduced by almost 80 per cent when more than a third of badgers in their group had been vaccinated.

The results come from a controlled clinical field trial of badger vaccination, conducted by the Animal Health and Veterinary Laboratories Agency (AHVLA) and the Food and Environment Research Agency (Fera), in an area in Gloucestershire where TB is highly prevalent in the badger population.

Dr Steve Carter of Fera and lead author of the latest research said: "One concern about the effectiveness of badger vaccination is that new-born cubs might acquire TB before they first emerge above ground. As the vaccine is not expected to benefit infected individuals it has been suggested that by the time cubs emerge and are available for vaccination they might have already been exposed to TB. Therefore, vaccination for them may be too late. This study indicates that vaccination of badgers above ground can indirectly protect unvaccinated cubs before they emerge from the sett".

The latest analyses were conducted by a team of scientists at Fera, AHVLA and the Universities of Newcastle and Strathclyde.

Professor Robbie McDonald, an author of the paper and now at the University of Exeter said: "This striking result in cubs shows a protective effect at the social group level and is important evidence that vaccination not only has a direct benefit to vaccinated badgers, but can also reduce the infectivity of TB within a badger social group that has been vaccinated."

But he cautioned: "Although this is an encouraging development, the costs and benefits of vaccinating badgers for controlling disease in cattle are not yet well understood".

"This means that it is a hard choice for farmers to make without further information and trials of how it would work in practice. The current Badger Vaccine Deployment Project in Gloucestershire and experience in the Welsh Government's badger vaccine project will help deliver this experience and knowledge."


Contact: Louise Vennells
University of Exeter

Related biology technology :

1. Masaryk Memorial Cancer Institute Reduces Losses and Administrative Overhead With Ekahau RTLS
2. R&D/Leverages New Opti-Sim Virtual Prototyping Tool Saves Time and Money for PET Packaging Industry -- and Reduces Waste
3. Computer vision reduces risk in clinical trials
4. Phase II Data Presented at ACNP 2012 Shows Novel Antidepressant GLYX-13 Significantly Reduces Depression Scores Within Hours
5. Members of Congress, Cancer Experts Address Impact of Genetic Testing on Cancer
6. LABS, Inc. Earns AABB Accreditation for Donor Testing
7. Sigma-Aldrich to Acquire BioReliance; Extending Its Reach into Biopharmaceutical Testing and Services
8. India In Vitro Diagnostics Market Outlook to 2017- Clinical Chemistry Genetic Testing, Haematology, Histology and Cytology, Immuno Chemistry, Infectious Immunology and Microbiology Culture
9. HPV Testing for Cervical Cancer Risk Patients set to Increase
10. Premier Research Expands Salt Lake City and Phoenix Testing Facilities Adding 50% Capacity
11. Arsenic Testing Proves Organic Baby Formula Safe
Post Your Comments:
(Date:11/26/2015)... England , November 26, 2015 ... an innovative medical device company specializing in imaging technologies, announced ... the European Commission as part of the Horizon 2020 European ... to carry out a large-scale clinical trial in breast cancer. ...      (Logo: , --> ...
(Date:11/25/2015)... 2 nouvelles études permettent d , ... les souches bactériennes retrouvées dans la plaque dentaire ... . Ces recherches  ouvrent une nouvelle voie ... de l,un des problèmes de santé les plus ... --> 2 nouvelles études permettent d , ...
(Date:11/25/2015)... , Nov. 25, 2015  Neurocrine Biosciences, Inc. ... Gorman , President and CEO of Neurocrine Biosciences, will ... Conference in New York . ... visit the website approximately 5 minutes prior to the ... replay of the presentation will be available on the ...
(Date:11/25/2015)... Nov. 25, 2015 Orexigen® Therapeutics, Inc. (Nasdaq: ... in a fireside chat discussion at the Piper Jaffray ... . The discussion is scheduled for Wednesday, December ... .  A replay will be available for 14 ... , Julie NormartVP, Corporate Communications and Business Development ...
Breaking Biology Technology:
(Date:11/4/2015)... , November 4, 2015 ... new market report published by Transparency Market Research "Home Security ... Trends and Forecast 2015 - 2022", the global home security ... 30.3 bn by 2022. The market is estimated to ... period from 2015 to 2022. Rising security needs among ...
(Date:10/29/2015)... Daon, a global leader in mobile biometric ... new version of its IdentityX Platform , IdentityX ... have already installed IdentityX v4.0 and are ... FIDO UAF certified server component as an option ... features. These customers include some of the largest and ...
(Date:10/29/2015)... 29, 2015 Today, LifeBEAM , ... with 2XU, a global leader in technical performance ... hat with advanced bio-sensing technology. The hat will ... monitor key biometrics to improve overall training performance. ... two companies will bring together the most advanced technology, ...
Breaking Biology News(10 mins):