Navigation Links
University of Colorado Cancer Center Review Shows Long-term Side-effects of New, Targeted Therapies in Pediatric Cancer Patients
Date:2/7/2013

ossible side-effects even in the short-term, let alone 10, 15 or 60 years later.

“The message I really want to convey is that our way of treating pediatric cancer has changed entirely in some diseases, and in some it’s meant huge progress. A number of us have patients who have literally been cured by these new drugs. There are a lot of really cool therapies out there, but the issue is using them safely. With increased survival, we need to cure kids for 60-70 years. The question is how do we best treat these kids, knowing that cancer remains the enemy but you also don’t want to induce complications that negatively affect the rest of their lives,” Gore says.

“Personally, one of the most important things when choosing how to treat pediatric patients is to know what I don’t know – to acknowledge gaps in knowledge. Then as a researcher, we try to fill these gaps so that we can prescribe knowing the balance of risk and reward for these treatments,” Porter says.

For now and until these questions are answered, the researchers recommend using molecularly targeted therapies with pediatric patients only in the context of a clinical trial. To Gore, Porter and co-author James DeGregori, PhD, the framework of a clinical trial provides the oversight needed for the rational prescription of these drugs in pediatric patients – along with follow-up that includes more definite monitoring of side-effects than what Gore describes as “random use.”

“One of the reasons we wrote this paper is that we don’t understand the major risks, or even what the major risks might be,” Porter says. “These targeted agents may affect the process of development in ways we can’t predict.”

Read the full story at http://www.prweb.com/releases/2013/2/prweb10409854.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. Elsevier and Kanazawa University in Japan Collaborate to Map Universitys Research Performance
2. Two University of Colorado Cancer Center Studies Show that Silibinin, Found in Milk Thistle, Protects Against UV-Induced Skin Cancer
3. WaferGens MyDesign Open Platform Facilitates Rapid Development of a Proprietary Prostate Cancer Diagnostic Panel in the Lab of Dr. Arul Chinnaiyan at the University of Michigan Cancer Center
4. NextBio Teams With Emory University and the Aflac Cancer Center to Improve Outcomes for Children with Medulloblastoma
5. Notre Dame to be part of $194 million university research center network
6. University of Minnesota awarded $28 million grant to lead microelectronics development
7. Krishagni Enables University of New South Wales (Australia) to Adopt caTissue Plus
8. University of Colorado Cancer Center Study Finds That Body's Ibuprofen, SPARC, Reduces Inflammation and Thus Bladder Cancer Development and Metastasis
9. Rice University discovers that graphene oxide soaks up radioactive waste
10. Carin Grings remains identified by researchers at Uppsala University
11. Nanonex Delivered Advanced Nanoimprint Tool NX-B200 to Swinburne University of Technology, Australia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Spartan Bioscience announced today that Health Canada ... It detects CYP2C19 genetic mutations in less than 60 ... RX CYP2C19 System is the first near-patient DNA test ... Due to the system’s ease of use, Health Canada ... professionals such as doctors, nurses, pharmacists, and laboratory technicians, ...
(Date:10/30/2014)... Al Khaimah, UAE (PRWEB) October 30, 2014 ... appointment of Dr. James A. Manganello, Chairman of the Board, ... of The Bahamas. The appointment was made by the ... Bahamas on September 24th, 2014. , More than ... Therapy and Research Bill , Prime Minister Perry Christie said ...
(Date:10/30/2014)... 2014  Regado Biosciences, Inc. (Nasdaq: RGDO ... call and live audio webcast on Thursday, November 6, ... quarter 2014 financial results. Interested participants and ... 347-1165 for domestic callers or (412) 902-4276 for international ... the investor relations section of the Regado website at ...
(Date:10/27/2014)... Ryan Carfley , Managing Partner at ... with Bryan Hamilton, the publisher of the Triangle Business Journal, ... the Research Triangle region of North Carolina. , Just a ... roundtable include the role of social media in recruitment, ... and the unique role that Millennials play in the workplace ...
Breaking Biology Technology:Health Canada approves first near-patient DNA test for personalized medicine 2Health Canada approves first near-patient DNA test for personalized medicine 3Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3Regado Biosciences to Provide Third Quarter 2014 Financial Results 2Personify's Ryan Carfley Talks Recruiting with Triangle Business Journal, RPG Solutions 2Personify's Ryan Carfley Talks Recruiting with Triangle Business Journal, RPG Solutions 3
... up a new Lake Superior chapter in Ashland in ... Wisconsin. , ,WIN organizes networking events, seminars and conferences. ... Council , a state-funded adviser to the governor and ... in Madison, Milwaukee, the Chippewa Valley and the Fox ...
... committee wrestles with balancing the state's biennial budget, calls ... Wisconsin System will likely move front and center. In ... one of the state's five biggest spending programs. , ... UW System programs that contribute to the state's economic ...
... fuel source for Wisconsin may be where consumers least expect ... Wisconsin Department of Administration announced on Monday a ... Madison Environmental Group consulting firm to develop cars operating ... restaurant chain Culver's , which has successfully modified two ...
Cached Biology Technology:Academic R&D pays for itself in jobs and economic growth 2Academic R&D pays for itself in jobs and economic growth 3Environmental group works to run cars on Culver's old frying oil 2Environmental group works to run cars on Culver's old frying oil 3
(Date:10/29/2014)... German . ... Schlögelhofer at the Max F. Perutz Laboratories (MFPL) of ... Vienna dived into the process of meiosis in specific ... inversion of the standard meiotic phases. The researchers describe ... Communications . , Meiosis is the two-step series of ...
(Date:10/29/2014)... Hebei, China — BGI Tech and Hebei Agricultural University ... Jujube genome. Jujube is the most economically important member ... particularly difficult to sequence due the high level of ... time that a genome in the Rhamnaceae (Buckthorn) family ... in Nature Communications . , Jujube ...
(Date:10/29/2014)... research by the international Cancer Genomics of the ... connection between kidney cancer and exposure to aristolochic ... findings, published in Nature Communications , have ... kills more than 140,000 people every year, and ... dramatically. CAGEKID, part of the International Cancer Genome ...
Breaking Biology News(10 mins):Meiotic cell division 'the other way round' 2BGI Tech and Hebei Agricultural University complete the genome sequencing of the jujube tree 2Kidney cancer in Central Europe 2
... are the destination for RRS James Cook,s current expedition. ... hydrothermal vents, calderas and cold seeps on the seabed ... Paul Tyler of the University of Southampton Ocean and ... Centre, the scientists are investigating four sites that were ...
... CHICAGO -- Northwestern Medicine researchers have discovered a ... cancer, with opposing functions that can suppress or promote ... (Treg) cells, known to suppress immune responses in healthy ... presence of the protein RORγt has been shown to ...
... Orleans, LA Kathleen Sebelius, Secretary of the United States ... Weiss, MD, Professor and Chair of the Department of Ophthalmology, ... of LSU Eye Center of Excellence at LSU Health Sciences ... Council. Effective immediately, she will serve a four-year term. Dr. ...
Cached Biology News:Finding life in the volcanic systems of the Antarctic Polar Front 2'Two-faced' cells discovered in colon cancer 2LSUHSC's Weiss chosen to help set national eye policy, research 2LSUHSC's Weiss chosen to help set national eye policy, research 3
Normal Hamster Serum...
... Short Stroke Thrust Slide is designed for ... envelopes are limited and substantial side-loading is ... bumpers provide millions of trouble-free cycles even ... composite bushings or recirculating ball bearings , ...
Alkaline Phosphatase (E. coli C75), 100 units. Removes 5'-phosphates from DNA. Category: Nucleotides & Enzymes & Biochemicals, Modifying Enzymes, Alkaline Phosphatases....
... Reactive Dye Pack, 12 x Cy5. ... optimized for microarray labeling.Higher reactivity Cy3 ... dye per vial, at > 75% ... dispensed, and packed in foil packs ...
Biology Products: