Navigation Links
University of Colorado Cancer Center Review Shows Long-term Side-effects of New, Targeted Therapies in Pediatric Cancer Patients
Date:2/7/2013

ossible side-effects even in the short-term, let alone 10, 15 or 60 years later.

“The message I really want to convey is that our way of treating pediatric cancer has changed entirely in some diseases, and in some it’s meant huge progress. A number of us have patients who have literally been cured by these new drugs. There are a lot of really cool therapies out there, but the issue is using them safely. With increased survival, we need to cure kids for 60-70 years. The question is how do we best treat these kids, knowing that cancer remains the enemy but you also don’t want to induce complications that negatively affect the rest of their lives,” Gore says.

“Personally, one of the most important things when choosing how to treat pediatric patients is to know what I don’t know – to acknowledge gaps in knowledge. Then as a researcher, we try to fill these gaps so that we can prescribe knowing the balance of risk and reward for these treatments,” Porter says.

For now and until these questions are answered, the researchers recommend using molecularly targeted therapies with pediatric patients only in the context of a clinical trial. To Gore, Porter and co-author James DeGregori, PhD, the framework of a clinical trial provides the oversight needed for the rational prescription of these drugs in pediatric patients – along with follow-up that includes more definite monitoring of side-effects than what Gore describes as “random use.”

“One of the reasons we wrote this paper is that we don’t understand the major risks, or even what the major risks might be,” Porter says. “These targeted agents may affect the process of development in ways we can’t predict.”

Read the full story at http://www.prweb.com/releases/2013/2/prweb10409854.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. Elsevier and Kanazawa University in Japan Collaborate to Map Universitys Research Performance
2. Two University of Colorado Cancer Center Studies Show that Silibinin, Found in Milk Thistle, Protects Against UV-Induced Skin Cancer
3. WaferGens MyDesign Open Platform Facilitates Rapid Development of a Proprietary Prostate Cancer Diagnostic Panel in the Lab of Dr. Arul Chinnaiyan at the University of Michigan Cancer Center
4. NextBio Teams With Emory University and the Aflac Cancer Center to Improve Outcomes for Children with Medulloblastoma
5. Notre Dame to be part of $194 million university research center network
6. University of Minnesota awarded $28 million grant to lead microelectronics development
7. Krishagni Enables University of New South Wales (Australia) to Adopt caTissue Plus
8. University of Colorado Cancer Center Study Finds That Body's Ibuprofen, SPARC, Reduces Inflammation and Thus Bladder Cancer Development and Metastasis
9. Rice University discovers that graphene oxide soaks up radioactive waste
10. Carin Grings remains identified by researchers at Uppsala University
11. Nanonex Delivered Advanced Nanoimprint Tool NX-B200 to Swinburne University of Technology, Australia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/19/2014)... (PRWEB) October 19, 2014 The ... Defense, & Homeland Security), Technology, Payload, Type & ... and segments the global unmanned ground vehicle market ... and forecasting of market sizes. The report also ... and opportunities impacting it along with the adoption ...
(Date:10/18/2014)... The Asian arthroscopic devices report defines and ... forecast of revenue. The arthroscopic devices market in Asia ... at a CAGR of 6.5% from 2013 to 2018. ... devices market, to get an idea of the in-depth ... segmentation of arthroscopic devices market in the same region, ...
(Date:10/18/2014)... According to a new market research report ... Global Trends & Forecasts up till 2017”, hydraulic fracturing ... This value is expected to increase from $40 billion ... CAGR during the same period. North America is expected ... terms of hydraulic horse power supplied by the year ...
(Date:10/17/2014)... and HILDEN, Germany , ... , Translational research in cancer and ... presented at the American Society of Human Genetics ... DNA samples linked to Ingenuity ®  Knowledge Base ... genomic analysis  Ingenuity ®  Variant Analysis™ ...
Breaking Biology Technology:Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 2Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 3Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) announced ... Science Innovation Northwest Conference on Thursday, March 3rd at ... Washington State Conference Center, Seattle, Washington. WBBA Life Science ... PST/1:25 PM EST/7:25 PM CETRoom 607, Washington State Conference ...
... Feb. 25, 2011 Cadence Pharmaceuticals, Inc. (Nasdaq: ... developing and commercializing proprietary product candidates principally for use in ... fourth quarter and full year ended December 31, 2010 financial ... management will host a conference call and live webcast to ...
... 25, 2011 Preventice, Inc. , ... that it will collaborate with Mayo Clinic to introduce ... technology. The first application from this collaboration is the ... gives physicians and patients instant access to information about ...
Cached Biology Technology:Preventice Announces Development of Mobile Health Application to Prevent and Improve Diagnosis of Skin Allergies 2
(Date:10/16/2014)... at William and Mary,s Virginia Institute of Marine ... the Environmental Protection Agency to identify the streams ... to develop tools to help local governments and ... depends critically on a dataset of tidal-marsh observations ... Only with this historical baseline can today,s researchers ...
(Date:10/16/2014)... causes severe respiratory tract infections and worldwide claims ... at VIB and Ghent University have succeeded in ... common virus infection. , Xavier Saelens (VIB/UGent): ... the way for the development of a novel ... causes suffering in numerous small children and elderly ...
(Date:10/15/2014)... to assess the pandemic risk from strains of influenza ... not allow ourselves to become complacent that the most ... of scientists. , Influenza pandemics arise when a new ... develop widespread immunity – spreads in the human population. ... 100 years, the worst of which – the 1918 ...
Breaking Biology News(10 mins):EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3New perspectives for development of an RSV vaccine 2Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2
... is available in German . Leipzig: ... and on water quality can now be assessed more easily. ... developed a tool that can estimate the harmful effect of ... agricultural land, within minutes. "It used to be very difficult ...
... of fiction,s Strange Case of Dr. Jekyll and Mr. Hyde, ... Medical School have found that a protein thought to protect ... The scientists, reporting in the Sept. 3 issue ... a transcription factor that regulates gene expression, becomes active when ...
... An award-winning Los Alamos National Laboratory sound-wave technology ... algae-based fuel in a cost-effective, scalable, and environmentally ... footprint of biofuel production. Algae innards contain ... lipids can be extracted by a relatively simple ...
Cached Biology News:Pesticides -- easier detection of pollution and impact in rivers 2Mayo Clinic researchers find that protein believed to protect against cancer has a Mr. Hyde side 2Los Alamos technology strikes a chord with algal biofuels 2
... to PRKAR2 cAMP is a signaling ... functions. cAMP exerts its effects by activating ... the signal through phosphorylation of different target ... a tetramer composed of two regulatory and ...
...
... a Perkin Elmer UltraVIEW system and want to ... and iQ software? No problem. Our experienced ... your existing microscope, lasers, Sutter filter wheel, Piezo ... work with our precision controller unit and workstation... ...
... instrument is the most advanced thermal cycler ... thermal performance, the Dyad also boasts graphical ... point-and-click navigation via touch pad or mouse. ... and economically expanded to a four-bay system ...
Biology Products: