“This is an interesting study demonstrating the potential of multipotent adult progenitor cells to serve as a universal cell product,” said Anthony Atala, MD, Editor of STEM CELLS Translational Medicine and director of the Wake Forest Institute for Regenerative Medicine. “Being able to reduce the level of immunosuppressant drugs post-transplant would have significant benefits to patients.”
The study team is now recruiting for a Phase I clinical trial to assess the safety profile of MAPC infusion in liver transplant recipients. Athersys is also conducting clinical trials in several other areas using MultiStem®, the clinical grade product being developed that utilizes the MAPC technology. The company also has a partnership with Pfizer to treat inflammatory bowel disease, which is the subject of an ongoing international Phase 2 clinical trial, and also has an ongoing Phase 2 clinical trial for treating patients that have suffered an ischemic stroke.
The full article, “Heart grafts tolerized through third-party Multipotent Adult Progenitor Cells can be re-transplanted to secondary hosts with no immunosuppression,” can be accessed at http://www.stemcellstm.com.
About STEM CELLS Translational Medicine: STEM CELLS TRANSLATIONAL MEDICINE (SCTM), published by AlphaMed Press, is a monthly peer-reviewed publication dedicated to significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices.
About AlphaMed Press: Established in 1983, AlphaMed Press with offices in Durham, NC, San Francisco, CA, and Belfast, Northern Ireland, publishes two other internationally r
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