Navigation Links
Universal Stem Cell Product Could Overcome Key Challenges in Donor Organ Transplants
Date:7/9/2013

Durham, NC (PRWEB) July 09, 2013

An international team of researchers published results demonstrating that a universal stem cell product increases the long-term survival of organ transplants in instances when the cell donor is neither related to the organ donor nor the organ recipient. Their approach also appears to alleviate the need for ongoing immune suppression.

In addition, the research demonstrates that the transplanted organ retained its immunologically privileged state during a subsequent transplantation into another naïve recipient.

The research, led by a team of transplant specialists at the University Hospital in Regensburg, Germany, developed the approach using a special class of stem cells referred to as multipotent adult progenitor cells (MAPCs). The MAPCs, collected from the bone marrow of a healthy donor, display a range of regenerative abilities and are already being used in clinical trials in several other areas, including for bone marrow transplant support, as well as for treating damage from stroke and heart disease and for certain autoimmune conditions. The study was conducted jointly with scientists at Erasmus University Medical Center, Rotterdam, and with a U.S.-based biotechnology company, Athersys Inc., in collaboration with scientists from the National Center for Regenerative Medicine based in Cleveland, Ohio.

“The immunological attributes of MAPCs make them a promising candidate for providing immunomodulatory support after organ transplantation,” explained Marc Dahlke, M.D., Ph.D., a lead investigator in the groundbreaking study that appears in the current issue of STEM CELLS Translational Medicine. “In contrast to other cell types, MAPCs can be expanded in a manner that makes them amenable to large-scale production, potentially making them an optimal choice for routine clinical use — especially in the so-called ‘third party’ scenario in which the cell donor is unrela
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. BioRealm to Develop Universal Genetic Screening Tool for Tobacco Addiction and Treatment
2. Family Tree DNA Unveils $39 DNA Test in Major Step Toward Universal Access by Individuals to their Own Genetic Data
3. Finesse Solutions Introduces SmartParts for Intelligent Universal Controllers
4. Kitware to Develop a Universal Healthcare Exchange Language Infrastructure
5. FDA Establishes New Product Codes for Interbody Devices With Integrated Fixation
6. Celebrating 65 Years of Providing Superior Healthcare Products, Mission Pharmacal Continues to Thrive
7. Liquid, Ammonium Ion-Free Glutathione Reductase Enzyme Introduced by Bio-Research Products
8. Life Technologies Ion Personal Genome Machine Receives San Diegos CONNECT Most Innovative New Product Award
9. CellerateRX® Added to List of Preferred Products for Golden Living Healthcare Network
10. Prolongs Large Scale Manufacturing of Sickle Cell Product to be Headed by Industry Veteran
11. Ecology Coatings Develops Coatings Safe for Direct Contact with Food Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... in the scientific journal PLoS One , ... effect of serotonin on sensitivity to pain using ... "Serotonin is a small molecule known to be ... from the control of sleep and appetite, to ... is also popularly thought to contribute to feelings ...
(Date:8/22/2014)... The Global and China Diabetes Drugs Industry ... state of the Diabetes Drug industry in Global and ... the industry, including definitions, applications and industry chain structure. ... provided with a focus on history, developments, trends and ... international and Chinese situation is also offered. , The ...
(Date:8/22/2014)... Nerium International, the go-to, buzzworthy skincare ... again. Nerium will showcase its signature NeriumAD® Age-Defying ... Cream to Hollywood’s elite at the official Giving ... Primetime Emmy® Awards. , Developed from cutting-edge research ... show that NeriumAD night cream dramatically reduces the ...
(Date:8/21/2014)... 21, 2014 DNA vaccine pioneer ... its development of JRC-LAMP-vax, an innovative and safe potential ... IC studies began this month in Hawaii, moving the ... , The Japanese red cedar releases pollen that causes ... Mountain Cedar pollen wreaks similar havoc in Colorado, New ...
Breaking Biology Technology:From happiness to pain: Understanding serotonin's function 2Diabetes Drugs Industry Growth Analysis in Global, China Regions Research Report Available at DeepResearchReports.com 2Diabetes Drugs Industry Growth Analysis in Global, China Regions Research Report Available at DeepResearchReports.com 3Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 2Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 3Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 4
... Biomedical, Inc., a privately held company developing and commercializing ... medicine for new and existing therapeutics, announced today that ... has been elected as chairman for the company,s board ... certified pathologist with more than 20 years experience in ...
... Rosetta Genomics, Ltd. (NASDAQ: ... molecular diagnostic tests, today announced the effectiveness of a ... reverse stock split, which was previously approved by the ... at the 2011 Annual General Meeting of Shareholders of ...
... the Universities of East Anglia, York and Nottingham and using ... hair, the researchers are working on harnessing the vast energy ... are presenting their research at the Royal Society,s annual Summer ... Members of the consortium at UEA have already found ...
Cached Biology Technology:Saladax Biomedical, Inc. Announces Appointment of Gregory C. Critchfield, M.D., M.S. as Chairman of the Company's Board of Directors 2Saladax Biomedical, Inc. Announces Appointment of Gregory C. Critchfield, M.D., M.S. as Chairman of the Company's Board of Directors 3Rosetta Genomics Announces One-For-Four Reverse Stock Split 2Rosetta Genomics Announces One-For-Four Reverse Stock Split 3Rosetta Genomics Announces One-For-Four Reverse Stock Split 4Putting sunshine in the tank 2
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ... it has agreed to a partnership with Gabriel ... fastest growing Certified Nursing Assistant ... Health Institute  an exclusive member of Binary,s LiveScan ... Binary Biometrics will improve its service capabilities ...
(Date:8/21/2014)... Nine researchers from Beth Israel Deaconess Medical ... "The World,s Most Influential Scientific Minds 2014," ... Reuters ScienceWatch, a web resource for science metrics and ... as among the most influential "are performing and publishing ... advancement of their science," according to a Thomson Reuters ...
(Date:8/21/2014)... a key region in the global oceanic circulation. "On the ... Atlantic water flows to the north into the Arctic Ocean ... sea ice push their way out of the Arctic into ... cools here on its way to the north and sinks ... this manner drives the global band of oceanic currents like ...
Breaking Biology News(10 mins):LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3BIDMC researchers named among 'the most influential scientific minds' 2BIDMC researchers named among 'the most influential scientific minds' 3Arctic sea ice influenced force of the Gulf Stream 2Arctic sea ice influenced force of the Gulf Stream 3
... -- Scientists at Weill Cornell Medical College have taken an ... uncovering evidence that it is not one disease, as previously ... in the future, destroyed by targeted therapy., ... Mark A. Rubin, the Homer T. Hirst Professor of Oncology ...
... are just some of the biological topics to which ... Mathematical and Biological Synthesis (NIMBioS) will host a tutorial ... models with an emphasis on biological applications. ... outcomes in order to predict what conditions might be ...
... Scientists are reporting the development of a simple, built-in ... and test strips for diagnosing diseases inexpensively at-home and ... Analytical Chemistry . Scott Phillips and Hyeran ... tests and others performed at home or bedside instead ...
Cached Biology News:Prostate cancer's multiple personalities revealed 2Tutorial addresses stochastic modeling in biological process 2Built-in timer for improving accuracy of cost saving paper-strip medical tests 2
... Simultaneously perform 96 assays on four ... four microarray slides with 96 (6mm x ... protein, gene expression, or screening analysis studies. ... compression fit gasket, eliminating the presence of ...
... is an automated multiplexing platform that uses ... pathogen sequence detection and pharmacogenetics applications. Multiple ... to an open and flexible electronic microarray, ... until all tests sites have been utilized. ...
... with sequence siTrio siRNA --- a ... target gene of interestis our most popular product. ... 75% knockdown of your target gene when used ... and confirmation of optimal transfection with one of ...
The Bio-Plex Manager version 3.0 to 4.0 workstation software upgrade kit is used to upgrade existing Bio-Plex Manager version 3.0 software to version 4.0 security edition software....
Biology Products: