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United Therapeutics Subsidiary Enters Into Contract With National Institutes of Health for Award of up to $45 Million to Support Glycobiology Antiviral Program
Date:10/10/2011

>About United Therapeutics Corporation

United Therapeutics is a biotechnology company focused on the development and commercialization of unique products to address the unmet medical needs of patients with chronic and life-threatening conditions. [uthr-g]

About Unither Virology

Unither Virology, LLC is a wholly-owned subsidiary of United Therapeutics Corporation. The company is the preclinical stage of developing a broad-spectrum antiviral drug to treat multiple viruses, such as dengue and influenza. Drug candidates have been shown to protect animals against multiple viruses, and the company is commencing a program to move toward potential clinical trials.

The company's glycobiology antiviral agents are being developed under a research agreement with the Oxford Glycobiology Institute. The antiviral agents consist of iminosugar molecules, which enter host cells and inhibit the chemical pathways that viruses use to fold their proteins. Because the iminosugars affect the host cell, rather than attacking the virus directly, they reduce the chance for drug-resistant virus strains to emerge. In laboratory tests, the iminosugar molecules have shown activity against several families of viruses. Unither Virology is conducting ongoing in vivo tests.

Forward-looking Statements

Statements included in this press release that are not historical in nature are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, among others, our expectations regarding the receipt of up to approximately $45 million in funding from NIH, the timing of any such funding, the prospects for future job creation and our ability to develop a broad-spectrum antiviral drug. These forward-looking statements are subject to certain risks and uncertainties, such as those described in our periodic and other reports filed with the Securities and Excha
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