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United Therapeutics Reports Fourth Quarter and Annual 2007 Financial Results
Date:2/19/2008

204 824 753

Stock option 3,671 2,600 12,373 9,240

Other 2,002 1,026 6,809 4,110

R&D expense from issuance of

common stock for license - - 11,013 -

Total research and

development expense $17,710 $18,337 $83,352 $57,570

Selling, general and administrative expenses consist primarily of salaries, travel, office expenses, insurance, professional fees, provision for doubtful accounts receivable, depreciation and amortization. The table below summarizes selling, general and administrative expenses by major categories for the three months and year ended December 31, 2007 and 2006 (dollars in thousands):

Three Months Ended Years Ending

December 31, December 31,

2007 2006 2007 2006

Category:

General and administrative $11,361 $7,300 $34,933 $25,434

Sales and marketing 7,826 4,584 24,159 14,438

Impairment charges 2,068 - 3,582 2,024

Stock option 22,971 7,303 36,353 14,156

Total selling, general

and administrative expense $44,226 $19,187 $99,027 $56,052

For the year ended December 31, 2007, as compared to the year ended December 31, 2006, the increase in general and administrative expenses was primarily related to increased expenses for salaries, associated expenses and other operating expenses from growth in our operations. The increase in sales and marketing related expenses was primarily related to increased salaries and an increase in headcount, marketing, travel and associated expenses from growth in our ope
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