$

201,020$

168,236$

546,784$

428,306License fees

7223391,221903Total revenues

201,742168,575548,005429,209Operating expenses:Research and development

59,43340,337131,379103,391Selling, general and administrative

16,65645,59398,775120,699Cost of product sales

22,67620,15563,57749,139Total operating expenses

98,765106,085293,731273,229Operating income

102,97762,490254,274155,980Other (expense) income:Interest income

1,0165642,5202,308Interest expense

(5,416)(4,809)(16,256)(14,255)Equity loss in affiliate

(43)(39)(110)(130)Other, net

(278)137(1,301)457Total other (expense) income, net

(4,721)(4,147)(15,147)(11,620)Income from continuing operations before income taxes

98,25658,343239,127144,360Income tax expense

(17,641)(18,217)(65,073)(47,332)Income from continuing operations

80,61540,126174,05497,028Discontinued operations:(Loss) income from discontinued operations, net of tax

—(390)7(656)Gain on disposal of discontinued operations, net of tax

3,783—618—Income (loss) from discontinued operations

3,783(390)625(656)Net income

$

84,398$

39,736$

174,679$

96,372Net income per common share:BasicContinuing operations

$

1.38$

0.71$

3.00$

1.74Discontinued operations

$

0.07$

(0.01)$

0.01$