Navigation Links
UTSA/UTHSCSA publish results on bio-threat agent
Date:9/23/2008

San Antonio (June 30, 2008) Researchers at The University of Texas at San Antonio (UTSA) South Texas Center for Emerging Infectious Diseases and The University of Texas Health Science Center at San Antonio (UTHSCSA) have identified a cell type believed to play a role in controlling the early infectious process against Francisella tularensis, a respiratory pathogen and bioterrorism agent that is the cause of tularemia. The findings will be released this week in a journal article in the Proceedings of the National Academy of Sciences.

The organism is considered to be a life-threatening bioterrorism agent by the Centers for Disease Control. Tularemia is an illness caused primarily by bites or scratches from rabbits, rodents and hares. In most cases, the bacterium causes relatively benign fever, chills and headaches that can be treated with antibiotics. However, when spread by aerosol, the organism can cause severe respiratory illness and systemic infections and is associated with a 30-40 percent mortality rate.

"We have found that mast cells, historically associated with allergic conditions and asthma, may also be involved in priming innate and adaptive immunity against tularemia," said Bernard Arulanandam, UTSA College of Sciences immunologist and associate professor of biology. "Our studies show that mast cells can interact with other cells and control the number of bacteria that replicate. This opens up a new dimension into how we look at mast cells against this organism, Francisella tularensis."

In 2005, the Department of Health and Human Services awarded UTSA's South Texas Center for Emerging Infectious Diseases a five-year $6.4 million grant to study tularemia.

Collaborators in the published study include Jyothi Ketavarapu, Annette Rodriguez, Karl Klose, Neal Guentzel, Thomas Forsthuber, Jieh-Juen Yu, Yu Cong, Ashlesh Murthy, and Bernard Arulanandam at UTSA, and Mike Berton with The UTHSCSA.

"I think this journal article shows the quality of the researchers that we have managed to attract to UTSA and we should be proud that important research is taking place on our campus as opposed to at a medical school someplace else," said Karl Klose, executive director of the South Texas Center for Emerging Infectious Diseases. "This is really a move in the right direction towards developing this university into a premier research institution."


'/>"/>

Contact: Marianne Lewis
marianne.lewis@utsa.edu
210-458-5141
University of Texas at San Antonio
Source:Eurekalert

Related biology technology :

1. UTSA/UTHSCSA publish results on bio-threat agent
2. UTSA/UTHSCSA publish results on bio-threat agent
3. Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
4. Sigma-Aldrich(R) Becomes First Life Science Company to Publish in Peer-Reviewed Video Journal JoVE
5. Sigma-Aldrich(R) Becomes First Life Science Company to Publish in PubMeds Peer-Reviewed Video Journal JoVE
6. More Evidence Published That Epidemics of Childhood Obesity, Type 2 Diabetes and Metabolic Syndrome are Linked to Immunization
7. PTC124 Shows Promising Activity in Cystic Fibrosis; Phase 2 Proof-of-Concept Data Published in the Lancet
8. The Scientific Business of Thomson Reuters Publishes Its 2008 Liquent Regulatory Affairs Trends Survey Results
9. Results of Study in Pre-School Children Published in Clinical Pediatrics Adds to Support for Importance of Dietary DHA Intake
10. The Protein Tomography(TM) Award Now Published on Sidecs Homepage
11. Regado Biosciences REG1 Anticoagulation System Study Results Published in the Journal of Thrombosis and Haemostasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/15/2017)... -- After spending the past two years building a state-of-the-art technology ... now offers this platform to healthcare stakeholders (hospitals, foundations, biopharma companies ... data collection vis a vis their members, under their own brand. ... this offer. ... ...
(Date:8/15/2017)... ... ... Any expert in stem cell research or stem cell medicine knows well the ... Despite their essential roles in human health and regenerative medicine, adult tissue stem ... this purpose also tag other, more abundant, non-stem tissue cells ( See 2017 Cell ...
(Date:8/15/2017)... ... August 15, 2017 , ... JULABO USA introduces ... the new website makes it easy to navigate through the site whether you’re ... find detailed product information, educational industry content and visit the company’s social media ...
(Date:8/11/2017)... , Aug. 11, 2017  Market ... New York Times article regarding the telemedicine ... according to Kalorama Information.  The article, ... for That"  used information from Kalorama ... Monitoring & Telemedicine Market  (Sleep, Diabetes, ...
Breaking Biology Technology:
(Date:6/23/2017)... ITHACA, N.Y. , June 23, 2017 /PRNewswire/ ... leader in dairy research, today announced a new collaboration ... reduce the chances that the global milk supply is ... dairy project, Cornell University has become the newest academic ... Supply Chain, a food safety initiative that includes IBM ...
(Date:5/6/2017)... 5, 2017 RAM Group , ... new breakthrough in biometric authentication based on a ... properties to perform biometric authentication. These new sensors are ... created by Ram Group and its partners. This sensor ... supply chains and security. Ram Group is a ...
(Date:4/13/2017)... 13, 2017 UBM,s Advanced Design and Manufacturing ... feature emerging and evolving technology through its 3D Printing ... run alongside the expo portion of the event and ... demonstrations focused on trending topics within 3D printing and ... manufacturing event will take place June 13-15, 2017 at the ...
Breaking Biology News(10 mins):