Navigation Links
UTSA/UTHSCSA publish results on bio-threat agent
Date:9/23/2008

San Antonio (June 30, 2008) Researchers at The University of Texas at San Antonio (UTSA) South Texas Center for Emerging Infectious Diseases and The University of Texas Health Science Center at San Antonio (UTHSCSA) have identified a cell type believed to play a role in controlling the early infectious process against Francisella tularensis, a respiratory pathogen and bioterrorism agent that is the cause of tularemia. The findings will be released this week in a journal article in the Proceedings of the National Academy of Sciences.

The organism is considered to be a life-threatening bioterrorism agent by the Centers for Disease Control. Tularemia is an illness caused primarily by bites or scratches from rabbits, rodents and hares. In most cases, the bacterium causes relatively benign fever, chills and headaches that can be treated with antibiotics. However, when spread by aerosol, the organism can cause severe respiratory illness and systemic infections and is associated with a 30-40 percent mortality rate.

"We have found that mast cells, historically associated with allergic conditions and asthma, may also be involved in priming innate and adaptive immunity against tularemia," said Bernard Arulanandam, UTSA College of Sciences immunologist and associate professor of biology. "Our studies show that mast cells can interact with other cells and control the number of bacteria that replicate. This opens up a new dimension into how we look at mast cells against this organism, Francisella tularensis."

In 2005, the Department of Health and Human Services awarded UTSA's South Texas Center for Emerging Infectious Diseases a five-year $6.4 million grant to study tularemia.

Collaborators in the published study include Jyothi Ketavarapu, Annette Rodriguez, Karl Klose, Neal Guentzel, Thomas Forsthuber, Jieh-Juen Yu, Yu Cong, Ashlesh Murthy, and Bernard Arulanandam at UTSA, and Mike Berton with The UTHSCSA.

"I think this journal article shows the quality of the researchers that we have managed to attract to UTSA and we should be proud that important research is taking place on our campus as opposed to at a medical school someplace else," said Karl Klose, executive director of the South Texas Center for Emerging Infectious Diseases. "This is really a move in the right direction towards developing this university into a premier research institution."


'/>"/>

Contact: Marianne Lewis
marianne.lewis@utsa.edu
210-458-5141
University of Texas at San Antonio
Source:Eurekalert

Related biology technology :

1. UTSA/UTHSCSA publish results on bio-threat agent
2. UTSA/UTHSCSA publish results on bio-threat agent
3. Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
4. Sigma-Aldrich(R) Becomes First Life Science Company to Publish in Peer-Reviewed Video Journal JoVE
5. Sigma-Aldrich(R) Becomes First Life Science Company to Publish in PubMeds Peer-Reviewed Video Journal JoVE
6. More Evidence Published That Epidemics of Childhood Obesity, Type 2 Diabetes and Metabolic Syndrome are Linked to Immunization
7. PTC124 Shows Promising Activity in Cystic Fibrosis; Phase 2 Proof-of-Concept Data Published in the Lancet
8. The Scientific Business of Thomson Reuters Publishes Its 2008 Liquent Regulatory Affairs Trends Survey Results
9. Results of Study in Pre-School Children Published in Clinical Pediatrics Adds to Support for Importance of Dietary DHA Intake
10. The Protein Tomography(TM) Award Now Published on Sidecs Homepage
11. Regado Biosciences REG1 Anticoagulation System Study Results Published in the Journal of Thrombosis and Haemostasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... Scientists at ... line options being tried for mesothelioma may be hampering the research that could lead ... research. Click here to read it now. , The team evaluated 98 ...
(Date:5/24/2016)... ... 24, 2016 , ... Cell therapies for a range of ... research at Worcester Polytechnic Institute (WPI) that yielded a newly patented method of ... The novel method, developed by WPI faculty members Raymond Page, PhD, professor of ...
(Date:5/23/2016)... ... May 23, 2016 , ... The need for blood donations in South Texas and across ... South Texas Blood & Tissue Center, blood donations are on the decline. In fact, donations ... are down 21 percent in South Texas in the last four years alone. , There ...
(Date:5/23/2016)... and LONDON , May 23, 2016 ... Frontage Boost Efficiency by 40% - Frontage Implement a ... Frontage Enforce Quality, Compliance and Traceability Within the Bioanalytical lab ... in the United States and ... be deployed across its laboratory facilities. In addition to serving as ...
Breaking Biology Technology:
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/15/2016)... 15, 2016  A new partnership announced today ... underwriting decisions in a fraction of the time ... and high-value life insurance policies to consumers without ... With Force Diagnostics, rapid testing (A1C, Cotinine and ... (blood pressure, weight, pulse, BMI, and activity data) ...
Breaking Biology News(10 mins):