Navigation Links
USC researchers derive first embryonic stem cells from rats
Date:12/24/2008

Researchers at the University of Southern California (USC) have, for the first time in history, derived authentic embryonic stem (ES) cells from rats. This breakthrough finding will enable scientists to create far more effective animal models for the study of a range of human diseases.

The research will be published in the Dec. 26 issue of the journal Cell.

"This is a major development in stem cell research because we know that rats are much more closely related to humans than mice in many aspects of biology. The research direction of many labs around the world will change because of the availability of rat ES cells," says Qi-Long Ying, Ph.D., assistant professor of Cell and Neurobiology at the Keck School of Medicine of USC, researcher at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, and the study's principal investigator.

The finding brings scientists much closer to creating "knockout" ratsanimals that are genetically modified to lack one or more genesfor biomedical research. By observing what happens to animals when specific genes are removed, researchers can identify the function of the gene and whether it is linked to a specific disease.

"Without ES cells it is impossible to perform precise genetic modifications for the creation of the disease model we want," he says. "The availability of rat ES cells will greatly facilitate the creation of rat models for the study of different human diseases, such as cancer, diabetes, high blood pressure, addiction and autoimmune diseases."

Ying, a native of China, notes that this breakthrough research occurred during 2008, the Chinese year of the rat.

Embryonic stem cells are derived from a group of cells called the inner cell mass in a very early stage embryo. ES cells provide researchers with a valuable tool to address fundamental biological questions, because they enable scientists to study how genes function, a
'/>"/>

Contact: Sara Reeve
sara.reeve@keck.usc.edu
323-442-2473
University of Southern California
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Clemson researchers advance nanoscale electromechanical sensors
2. Duke researchers coax bright white light from unexpected source
3. Pitt researchers create nontoxic clean-up method for potentially toxic nano materials
4. USC researchers print dense lattice of transparent nanotube transistors on flexible base
5. J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology
6. Virginia Tech researchers discover how mosquitoes avoid succumbing to viruses they transmit
7. Alfred Mann Foundation for Biomedical Engineering Launches New Web Site Designed to Help University Researchers Bring Biomedical Advances to Market
8. 2010 Japan Prize to Honor Scientists and Researchers in Industrial Production/Production Technology and Biological Production/Environment Fields
9. Clemson researchers advance nanoscale electromechanical sensors
10. Researchers discover method for mass production of nanomaterial graphene
11. VAP(R) Cholesterol Test Helps Researchers Identify Treatment Effects of Combination Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... GLASGOW, Scotland , September 17, 2014 ... a new mode of action from a ... a decade  MGB Biopharma, a ... of anti-infectives, announces today that it has ... of its lead antibacterial, MGB-BP-3, against a ...
(Date:9/16/2014)... Washington, USA (PRWEB) September 16, 2014 ... to create the features that we desire in optical ... Center at Montana State University. “As we explore surfaces ... Some of those lessons were presented in San Diego ... of Light: Light in Nature ” chaired by Shaw ...
(Date:9/16/2014)... 16, 2014 --The emerging field of molecular electronics ... next level, enabling the construction of tiny circuits ... individual molecules would take on the roles currently ... A team of researchers from five Japanese and ... use in small-scale electronics: a molecule called picene. ...
(Date:9/16/2014)... HILL, N.C. , Sept. 16, 2014 ... experimental heart failure compound has been shown to be ... preclinical results demonstrate an alternative to intravenous infusions that ... HNO prodrugs. The data were presented yesterday at the ... Annual Scientific Meeting in Las Vegas ...
Breaking Biology Technology:MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 2MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 3MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 4MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 5MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 6MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 7Nature’s designs inspire research into new light-based technologies 2Nature’s designs inspire research into new light-based technologies 3Nature’s designs inspire research into new light-based technologies 4Nature’s designs inspire research into new light-based technologies 5The future face of molecular electronics 2Cardioxyl Presents Oral Heart Failure Treatment Data For Its Experimental HNO Prodrug At HFSA 18th Annual Scientific Meeting 2
... DIEGO, April 15 Mr. Glynn has over 34 ... is well,known within the life sciences industry for his ... Most notably, Mr. Glynn,retired from Invitrogen Corporation (Nasdaq: ... company, he held several operating roles including CFO,President and ...
... NEW HAVEN, Conn., April 15 Vion,Pharmaceuticals, Inc. (Nasdaq: ... a,plan to achieve and sustain compliance with The Nasdaq ... of the plan., Previously, the Company announced that ... The Nasdaq Stock Market, Inc., notifying the Company,that it ...
... April 15 SGX Pharmaceuticals, Inc.,(Nasdaq: SGXP ) ... the,American Association for Cancer Research (AACR) in San Diego. ... of the HGF,receptor tyrosine kinase (MET), inhibits growth of ... the afternoon poster session,entitled Small Molecule Kinase Inhibitors 1 ...
Cached Biology Technology:eBioscience Corporation Announced Today That James Glynn Has Been Appointed to Its Board of Directors, Effective April 15, 2008 2Vion Pharmaceuticals Files Plan With Nasdaq 2Vion Pharmaceuticals Files Plan With Nasdaq 3SGX Presents Preclinical MET Data at AACR 2SGX Presents Preclinical MET Data at AACR 3
(Date:9/17/2014)... Trees have been growing significantly faster since the 1960s. ... barely changed, but they have accelerated -- by as ... a study carried out by scientists from Technische Universitt ... that have been continuously observed since 1870. Their findings ... Three decades ago, "forest dieback" was a hot topic, ...
(Date:9/16/2014)... women in Australia is increased by lower socioeconomic ... September) in BJOG: An International Journal of ... high standards of living; however, existing research has ... indigenous and non indigenous Australians. , This case-control ... socioeconomic position on severe maternal morbidities associated with ...
(Date:9/16/2014)... taught us that we inherit certain traits from our ... change how these genes play out by taking certain ... That,s exactly what a team of researchers at the ... their research of epigenetics research. , Epigenetics regulates ... DNA and histone proteins, which prevent permanent mutations or ...
Breaking Biology News(10 mins):Global change: Trees continue to grow at a faster rate 2Global change: Trees continue to grow at a faster rate 3New study examines the impact of socioeconomic position & maternal morbidity in Australia 2New study examines the impact of socioeconomic position & maternal morbidity in Australia 3Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 2Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 3
... MCLEAN, Va., Nov. 29, 2012  Northrop Grumman Corporation (NYSE: ... proof of concept for an automated biometric information system ... will be operated for a trial period to enable ... enabled intelligence and to help determine the requirements for ...
... William Cooke, a professor in the UTSA College of Education ... selected to serve as the speaker of the Texas Chapter ... Tour. Over the course of a week, Cooke will deliver ... of ACSM,s Texas Chapter. "This is a big honor ...
... For the first time in its history, the American Society ... opening session of the ASCB,s Annual Meeting, for "An Evening ... Francisco, on Saturday, Dec. 15. Members of the ... will receive complimentary registration to the ASCB keynote addresses ...
Cached Biology News:Northrop Grumman Delivers Australian Automated Biometric Information System Trial Proof of Concept 2UTSA physiologist William Cooke named 2013 Lecture Series Speaker by Texas Sports Medicine Chapter 2Public invited to 'An Evening of Science & Art' at ASCB Annual Meeting 2
RAT ANTI MOUSE F4/80 ANTIGEN:BIOTIN Immunogen: Thioglycollate stimulated peritoneal macrophages from C57/BL mice...
SHEEP ANTI FLECAINIDE...
ANTI PIG LDH H4...
RAT ANTI MOUSE F4/80 ANTIGEN:BIOTIN Immunogen: Thioglycollate stimulated peritoneal macrophages from C57/BL mice...
Biology Products: