Navigation Links
USC researchers derive first embryonic stem cells from rats
Date:12/24/2008

Researchers at the University of Southern California (USC) have, for the first time in history, derived authentic embryonic stem (ES) cells from rats. This breakthrough finding will enable scientists to create far more effective animal models for the study of a range of human diseases.

The research will be published in the Dec. 26 issue of the journal Cell.

"This is a major development in stem cell research because we know that rats are much more closely related to humans than mice in many aspects of biology. The research direction of many labs around the world will change because of the availability of rat ES cells," says Qi-Long Ying, Ph.D., assistant professor of Cell and Neurobiology at the Keck School of Medicine of USC, researcher at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, and the study's principal investigator.

The finding brings scientists much closer to creating "knockout" ratsanimals that are genetically modified to lack one or more genesfor biomedical research. By observing what happens to animals when specific genes are removed, researchers can identify the function of the gene and whether it is linked to a specific disease.

"Without ES cells it is impossible to perform precise genetic modifications for the creation of the disease model we want," he says. "The availability of rat ES cells will greatly facilitate the creation of rat models for the study of different human diseases, such as cancer, diabetes, high blood pressure, addiction and autoimmune diseases."

Ying, a native of China, notes that this breakthrough research occurred during 2008, the Chinese year of the rat.

Embryonic stem cells are derived from a group of cells called the inner cell mass in a very early stage embryo. ES cells provide researchers with a valuable tool to address fundamental biological questions, because they enable scientists to study how genes function, a
'/>"/>

Contact: Sara Reeve
sara.reeve@keck.usc.edu
323-442-2473
University of Southern California
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Clemson researchers advance nanoscale electromechanical sensors
2. Duke researchers coax bright white light from unexpected source
3. Pitt researchers create nontoxic clean-up method for potentially toxic nano materials
4. USC researchers print dense lattice of transparent nanotube transistors on flexible base
5. J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology
6. Virginia Tech researchers discover how mosquitoes avoid succumbing to viruses they transmit
7. Alfred Mann Foundation for Biomedical Engineering Launches New Web Site Designed to Help University Researchers Bring Biomedical Advances to Market
8. 2010 Japan Prize to Honor Scientists and Researchers in Industrial Production/Production Technology and Biological Production/Environment Fields
9. Clemson researchers advance nanoscale electromechanical sensors
10. Researchers discover method for mass production of nanomaterial graphene
11. VAP(R) Cholesterol Test Helps Researchers Identify Treatment Effects of Combination Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... BIOEQUA, an innovative line of skin care ... handheld spray, has made its EQUA ESSENTIAL line available ... brand began with an unexpected discovery in an emergency ... that the application of nanospray technology allowed for liquid ... to skin's basal layer. This resulted in immediate absorption ...
(Date:8/27/2014)... State College, PA (PRWEB) August 27, 2014 ... Electromagnetic Simulation Software with new features for the ... release is an enhanced Biological Thermal Sensor, exclusive to ... is a specialty version of XFdtd, developed to calculate ... MATLAB® export functionality has been added to all versions ...
(Date:8/26/2014)... the thinnest-possible semiconductor, a new class of nanoscale ... , The University of Washington researchers have demonstrated ... be connected in an atomically seamless fashion known ... basis for next-generation flexible and transparent computing, better ... "Heterojunctions are fundamental elements of electronic and photonic ...
(Date:8/26/2014)... 2014 An analysis by Replikins, Ltd. of ... Mers CoV virus strains has revealed extensive conservation ... This conservation and sharing of specific Replikin gene structures ... candidate, as it did for the H5N1 influenza vaccine ... have been found to be effective (1,2). ...
Breaking Biology Technology:BIOEQUA'S EQUA ESSENTIAL Product Line Redefines Skin Care & Now Available in America 2Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 2Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 3Scientists craft atomically seamless, thinnest-possible semiconductor junctions 2
... ... Improvements. Producers, breed associations, livestock researchers and processing laboratories now have access to ... ability to accelerate breed improvements and verify parentage for cattle, sheep and swine. ... ...
... , ATLANTA, Jan. 8 With the ... might affect industrial boiler emissions, Georgia Power has decided to ... to biomass until the EPA rules are better defined in ... ) , The anticipated industrial boiler Maximum Achievable Control ...
... ... stage biopharmaceutical company focused on the development of novel vaccine candidates to treat chronic ... investor conference and will be attending the J.P. Morgan Healthcare Conference in San Francisco. ... Baltimore, MD ...
Cached Biology Technology:DNA Genotek Launches New Sample Collection Product to Accelerate Livestock Genetic Testing 2DNA Genotek Launches New Sample Collection Product to Accelerate Livestock Genetic Testing 3DNA Genotek Launches New Sample Collection Product to Accelerate Livestock Genetic Testing 4Georgia Power to Delay Plant Mitchell Conversion to Biomass 2Profectus Biosciences to Present at Key Investor Conference in January 2010 2Profectus Biosciences to Present at Key Investor Conference in January 2010 3
(Date:8/26/2014)... 2014 Oxygen ... Passware Analyst bekannt, einem neuen mobilen kriminaltechnischen ... Analysetools von Oxygen mit der Kennwortwiederherstellung und ... Das neue Tool kombinierte mobile Erfassung, Datenextraktion, ... Ablauf. Das neu hinzugekommene Modul für Kennwortwiederherstellung ...
(Date:8/25/2014)... is one of the most widespread causes of reduced ... United States are plagued by boron deficient soil and, ... their soil with boron; however, little is known about ... nutrient. Now, researchers at the University of Missouri have ... and reproduction in corn plants. Scientists anticipate that understanding ...
(Date:8/25/2014)... of biomolecule built like a nano-Christmas tree. Called a ... , It,s those ornaments that get all the glory. ... "tree" basically holds the sugars in place as they ... , Now a chemist at Michigan Technological University has ... deal more than a simple prop. , "We had ...
Breaking Biology News(10 mins):Oxygen Forensic Passware Analyst erfasst geschützte Mobilgerätedaten 2Researchers find boron facilitates stem cell growth and development in corn 2
... led by Northwestern Medicine scientists has identified how a defective ... disease known as Giant Axonal Neuropathy, or GAN. The finding ... Investigation . GAN is an extremely rare and ... systems of young children. Those affected show no symptoms at ...
... Health today announced that Vetsulin (porcine insulin zinc suspension), the ... is now available to veterinarians throughout the United States. ... from one in 1001 to one in 500, 2 and ... during the past 30 years.3 Today, along with proper diet ...
... cat, it instinctively avoids the feline or risks becoming dinner. ... the sense of smell, provides evidence that a single gene ... by neurobiologist Thomas Bozza has shown that removing one olfactory ... behavior. The gene, called TAAR4, encodes a receptor that responds ...
Cached Biology News:Rare, lethal childhood disease tracked to protein 2Merck Animal Health announces Vetsulin 2Cat and mouse: A single gene matters 2Cat and mouse: A single gene matters 3
... The H2OBIT™ is a fully licensed, high throughput, ... processing of up to 24 microplates. This equates ... plates. A robotic arm rapidly transfers ... resulting in temperature ramping times that are considerably ...
... ONE Ribonuclease is a 27kDa periplasmic enzyme ... of RNA to cyclic nucleotide monophosphate (NMP) ... of these intermediates to 3-NMPs (1). RNase ... known RNases that can cleave a phosophodiester ...
Porcine Pulmonary Artery Endothelial Cells (PPAEC) (>500,000 cells)...
...
Biology Products: