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US Neuropathic Pain Market Value Doubles to $5 Billion by 2018
Date:9/11/2008

ndrome, HIV/AIDS neuropathy, post-herpetic neuralgia, phantom limb pain, spinal cord injury, and trigeminal neuralgia). Insights have also been added from WWMR's US Pain Clinic Monitor -- an audit of more than 100 pain clinics containing prescribing and condition details on more than 5000 patients -- many of whom have neuropathic pain.

Worldwide, approximately 76 agents are in active clinical trials for the treatment of neuropathic pain, and are reviewed in this report. Five new neuropathic pain treatments are currently registered or pre-registered with the FDA for NP marketing approval: lacosamide (Schwarz Pharma), milnacipran (Forest Laboratories/Cypress Bioscience), transdermal capsaicin (NeurogesX) and a dual cannabinoid receptor agonist (GW/Bayer), and fentanyl buccal (Cephalon). Eighteen drugs are in Phase III development in the US including two GABA receptor agonists pregabalin (Pfizer) and gabapentin GR (Depomed); a sodium channel antagonist mexiletine (Boehringer Ingelheim); three glutamate / NMDA antagonists ketamine intranasal (Javelin), a dextromethorphan/quinidine combination (Avanir), and NP-1 (EpiCept/Epitome); two serotonin/norepinephrine reuptake inhibitors desvenlafaxine (Wyeth), and paroxetine (GSK/Novo Nordisk); an alpha-2 adrenergic receptor antagonist/norepinehrine reuptake inhibitor reboxetine (Pfizer); an opioid receptor agonist/norepinephrine reuptake inhibitor tapentadol (Ortho-McNeil); a dopamine receptor agonist sodium oxybate (Jazz), and a neuromuscular blocking agent botulinum toxin A (Allergan). Early-phase products are also described in the full report.

ADDITIONAL SERVICES AND REPORTS BY WWMR, INC. INCLUDE:

-- US Pain Clinic Monitor (available now)

-- 2008 European Neuropathic Pain (coming soon)

-- 2008 Japanese Neuropathic Pain (coming soon)

WWMR, Inc. is a leader in Pain Reporting, and also designs and executes research which brings clarity, reveals innovative opportunities and provides
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SOURCE WWMR, Inc.
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