Navigation Links
UCLA physicists report nanotechnology feat with proteins
Date:12/19/2011

The new measurements, by UCLA physics professor Giovanni Zocchi and former UCLA physics graduate student Yong Wang, are approximately 100 times higher in resolution than previous mechanical measurements, a nanotechnology feat which reveals an isolated protein molecule, surprisingly, is neither a solid nor a liquid. "Proteins are the molecular machines of life, the molecules we are made of," Zocchi said. "We have found that sometimes they behave as a solid and sometimes as a liquid.

"Solids have a shape while liquids flow for simple materials at low stresses. However, for complex materials, or large stresses, the behavior can be in-between. Subjected to mechanical forces, a material might be elastic and store mechanical energy (simple solid), viscous and dissipate mechanical energy (simple fluid), or visco-elastic and both store and dissipate mechanical energy (complex solid, complex fluid). The viscoelastic behavior characteristic of more complex matter had not been clearly seen before on isolated proteins because mechanical measurements tend to destroy the proteins."

Zocchi and Wang's new nanotechnology method allowed them to apply stresses and probe the mechanics of the protein without destroying it. Wang, now a physics postdoctoral fellow at the University of Illinois in UrbanaChampaign, and Zocchi discovered a "transition to a viscoelastic regime in the mechanical response" of the protein.

"Below the transition, the protein responds elastically, like a spring," Zocchi said. "Above the transition, the protein flows like a viscous liquid. However, the transition is reversible if the stress is removed. Functional conformational changes of enzymes (changes in the shape of the molecule) must typically operate across this transition."

The measurements were performed on the enzyme guanylate kinase, or GK, a member of an essential class of enzymes called kinases. Specifically, GK transfers a phosphate group from ATP (th
'/>"/>

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related biology technology :

1. UCSB physicists identify room temperature quantum bits in widely used semiconductor
2. Physicists to develop new way of electronic computing
3. UCSB physicists demonstrate the quantum von Neumann architecture
4. Penn physicists undo the coffee ring effect
5. Penn physicists observe campfire effect in blinking nanorod semiconductors
6. Physicists measure current-induced torque in nonvolatile magnetic memory devices
7. Penn physicists develop scalable method for making graphene
8. Physicists isolate bound states in graphene-superconductor junctions
9. UCSB physicists challenge classical world with quantum-mechanical implementation of shell game
10. Physicists take new look at the atom
11. Rice physicists discover ultrasensitive microwave detector
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... TransVac Solutions, the trusted leader in automated ... for hospitals, will be exhibiting at booth #209 at ... & Technical Exhibition Aug. 3-6 in Chicago, Ill. ... hospitals cleaner, reducing infection risk and saving millions in ... Staff will be available at booth #209 to ...
(Date:7/29/2014)... Hill, South Carolina (PRWEB) July 29, 2014 ... with teams of people where cell phone masts or other ... iPhones up to 100 feet away without the need for ... to target longer ranges. , The new app has launched ... of US homes are at very high risk of being ...
(Date:7/29/2014)... Eppendorf Centrifuge 5427 R has ... R is geared towards high-end applications like genomic, atomic, ... towards work requiring high sample throughput. Pipette.com is excited ... their extensive 16, 48, and 64 multichannel pipettes as ... tubes, PCR strip tubes, and more. , Introducing ...
(Date:7/29/2014)... , July 29, 2014 ... System (LBS) zur Erfassung biologischer Daten in ... entwickelt und patentiert. Das LBS nimmt gleichzeitig ... Koronararterie des Patienten und sucht erhöhte biologische ... das Potenzial, die Entdeckung und Entwicklung neuer ...
Breaking Biology Technology:TransVac Presents Cost Saving Technology at ASHE Conference for Keeping Hospitals Cleaner 2DisasterTalk App Could Save Lives as Report Reveals 8% of US Homes at Very High Risk of Natural Disaster 2International Pipette Distributor, Pipette.com Announces the Addition of the Eppendorf Centrifuge 5427 R to Their Product Portfolio 2PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 2PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 3PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 4
... In the merger, each outstanding share of common stock of ... either 0.63 shares of common stock of Bruker Daltonics or, ... to be of equivalent value, payable 75% in Bruker Daltonics ... stock of Bruker Daltonics are not being changed in the ...
... the development and use of devices that are one-billionth ... importance as a science, and the term now describes ... less than 1,000 nanometers of the substances involved in ... in the creation of exciting and innovative new products ...
... labs, technology, research, communication and planning , ,WASHINGTON ... the Department of Health and Human Services has made ... of states, territories and metro areas to respond to ... to receive $25 million, of which almost $16 Million ...
Cached Biology Technology:Bruker Daltonics and Bruker AXS Announce Merger Agreement 2Nanotechnology - Natures Lego Blocks! 2Wisconsin to Receive $25 Million for Bioterrorism 2
(Date:7/29/2014)... overseas territory of Ascension Island, one of the world,s ... renaissance. , Writing in the journal Biodiversity and ... Ascension Island Government Conservation Department report that the number ... outpost has increased by more than 500 per cent ... 24,000 nests are now estimated to be laid on ...
(Date:7/29/2014)... 2014  When it comes to technology, healthcare is usually one ... last. However, when it comes to wearables, healthcare is trying to ... the Internet of Things and its wearable cousins is less than ... healthcare industry, whether it,s in the hospital for a major procedure ... With that in mind, InformationWeek editor Rodney Brown ...
(Date:7/29/2014)... Schools of Dentistry (UM SOD) and Medicine (UM ... a five-year $10.7 million grant award from the ... of the National Institutes of Health to study ... (STDs). The grant, which renews a previous $12 ... direction for the research by studying chlamydial and ...
Breaking Biology News(10 mins):Major turtle nesting beaches protected in 1 of the UK's far flung overseas territories 2University of Maryland Schools of Dentistry and Medicine receive NIH grant 2University of Maryland Schools of Dentistry and Medicine receive NIH grant 3University of Maryland Schools of Dentistry and Medicine receive NIH grant 4
... Valley, NY. (Dec. 20, 2012) When different types ... them aid in repairing central nervous system (CNS) trauma, ... A Belgian research team carried out research aimed at ... cells - neural stem cells, mouse embryonic fibroblasts, dendritic ...
... U.S. Secretary of the Interior Ken Salazars announcement of ... (NPR-A) that balances wildlife conservation and energy development in ... Integrated Activity Plan and Final Environmental Impact Statement (Final ... is the first comprehensive land management plan ever developed ...
... Emeritus of the department of dermatology at Boston University School ... has been named a 2012 Charter Fellow of the National ... End, is among four faculty members at Boston University nominated ... fellows, who are elected by their peers, represent 98 innovators ...
Cached Biology News:Cell Transplantation study investigates fate and function of cells transplanted to the CNS 2WCS applauds Dept. of Interior plan balancing conservation and energy development in NPR-A 2
... Virgin, optically clear polystyrene with frosted ... coordinates for cell counting. 100% integrity ... a new product number, created to ... showing no availability yet, please order ...
Automated Cell Culture Flask...
... 100-240 V, uses multiplex suspension array technology ... up to 100 proteins and peptides in ... is composed of up to 100 color-coded ... conjugated with a unique reactant specific to ...
...
Biology Products: