Navigation Links
UCF team developing tool kit to help diagnose dementia
Date:9/29/2009

With the risk of developing dementia growing at an alarming pace, a University of Central Florida research team is working with the Boston University School of Medicine to develop a miniature diagnostic toolkit in the hopes of stimulating earlier detection and treatment.

The collaborative research project, funded by the National Science Foundation for up to $600,000 over three years, will use nanoparticles on a chip about the size of a credit card to detect damaging levels of oxygen byproducts in the central nervous system.

The byproducts, known as reactive oxygen species (ROS), are major contributors to serious neurodegenerative diseases, including Alzheimer's and Parkinson's.

The development of new analytical tools for speeding up diagnosis and treatment of these disorders is critical if we hope to slow their growth, said lead researcher Hyoung Jin Cho, an associate professor of Mechanical, Materials and Aerospace Engineering at the University of Central Florida and a researcher at UCF's NanoScience Technology Center.

The number of people with dementia, which is the primary precursor to Alzheimer's, will almost double every 20 years, reaching 65.7 million in 2030 and 115.4 million in 2050, according to the 2009 World Alzheimer Report from Alzheimer's Disease International. The report, issued last week in recognition of World Alzheimer's Day, calls for making the fight against the disease a national and global priority.

"This research shows significant potential for better understanding the role of ROS in neurodegenerative diseases," said Cho. "Once we have a clearer understanding of the role of ROS, we may be able to address more effective treatments."

Existing tests have several drawbacks. They are only able to detect limited numbers of significant byproducts at a time; they require time-consuming and labor-intensive processing; and they don't work quickly enough to keep up with the short lifespan of most of the byproduct
'/>"/>

Contact: Zenaida Gonzalez Kotala
zkotala@mail.ucf.edu
407-823-6120
University of Central Florida
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Microchip Biotechnologies, Inc. Secures Exclusive License to Use New University of Alberta Technology for Developing Microfluidic Devices
2. DuPont, Genencor International and Tate & Lyle Honored for Groundbreaking Work in Developing Bio-PDO(TM)
3. International Atomic Energy Agency and National Foundation for Cancer Research Launch Major Initiative to Improve Cancer Prevention and Treatments in Developing Countries
4. Free CME-certified Webcast: Making Your Case: Up-to-date Answers for Developing Trends in PCI
5. The Diabetes Series 2008: Experts Speak About Developing Diabetes Therapeutics
6. Microchip Biotechnologies, Inc. Collaborating With Stanford University on Developing a Front End Microfluidic-Based Sample Preparation System for Pyrosequencing Platforms
7. Allen Institute for Brain Science Launches Three New Landmark Atlas Projects Focusing on the Human Brain, Developing Brain and Spinal Cord
8. Genetic Engineering & Biotechnology News reports on clinical trials in developing countries
9. Iowa State researchers developing system to efficiently convert biomass to ethanol
10. Pharmaceuticals & Biotechs to Share Insights for Developing Leaders in a Fast-Paced, Competitive Industry
11. Developing Sales Leaders: Benchmarks Reveal Tactics that Will Propel Your Business
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCF team developing tool kit to help diagnose dementia
(Date:8/21/2014)... Emmetsburg, IA (PRWEB) August 21, 2014 ... Project LIBERTY Opening , The Court of His Majesty ... King will attend the Grand Opening of POET-DSM Advanced ... on Wednesday, Sept. 3. , The King will take ... formal opening activity, scheduled for 11 a.m.-12:20 p.m. and ...
(Date:8/21/2014)... 21, 2014 The College of New ... college in the Mid-Hudson Region to be designated as ... accepting applications from qualified “high-technology” businesses that align with ... pleased to have been selected for the START-UP NY ... initiative to stimulate economic development in New York by ...
(Date:8/21/2014)... Mathematic studies at the Program for Evolutionary ... by the Jeffrey Epstein VI Foundation , have shown ... identified for elimination. These aggressive cells are the driver mutations ... topological map of what to look for when examining tumors, ... tumor cells can be extracted from biopsy, it,s very difficult ...
(Date:8/21/2014)... Aug. 21, 2014  China Cord Blood Corporation (NYSE: ... to release financial results for the first quarter of ... market close in the US.  The ... ET on Friday, August 29, 2014 to discuss its ... Company,s recent developments, followed by a question and answer ...
Breaking Biology Technology:His Majesty Willem-Alexander, King of the Netherlands, to Attend Project LIBERTY opening 2His Majesty Willem-Alexander, King of the Netherlands, to Attend Project LIBERTY opening 3The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3Science Power Jeffrey Epstein and Harvard University Fund Project to Visually Stop Tumor Growth 2China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2
... , Bio-Rad Laboratories, Inc., Hercules, CA 94547 ... Introduction , ... that can be used to screen DNA fragments for small sequence ... denaturing environment is created by a combination , ...
... Hercules, CA 94547 USA, , ... In chromatographic separations, sample component elution times are often , ... automated chromatography steps , like fraction collection. ... chromatographic separations is essential. In order to achieve reproducible , ...
... Chris Moran, Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Dr., Hercules, , ... , Introduction ... to explore the structure , and function of ... strategies use experimental conditions where proteins of interest are , ...
Cached Biology Technology:DGGE Analysis Using the DCode System, Rev B 2DGGE Analysis Using the DCode System, Rev B 3Separation Reproducibility With the BioLogic Chromatography Systems 2Separation Reproducibility With the BioLogic Chromatography Systems 3Rapid Chromatography Optimization by pH Scouting Using the New BioLogic Maximizer Valve System, Rev A 2Rapid Chromatography Optimization by pH Scouting Using the New BioLogic Maximizer Valve System, Rev A 3Rapid Chromatography Optimization by pH Scouting Using the New BioLogic Maximizer Valve System, Rev A 4
(Date:8/20/2014)... CITY Researchers at Huntsman Cancer Institute (HCI) at the ... of the gene that encodes BCR-ABL, the unregulated enzyme ... to the American Cancer Society, nearly 6,000 new cases ... already in use, called tyrosine kinase inhibitors (TKIs), target ... do not cure CML but control it in a ...
(Date:8/20/2014)... University, the Wellcome Trust Sanger Institute and the Swiss ... Mycobacterium pinnipedii from skeletons found in Peru which ... a relative of the TB bacterium that affects seals ... researchers assume that seals carried the pathogens from Africa ... was unexpected" comments Sebastien Gagneux, from the Swiss Tropical ...
(Date:8/20/2014)... SILICON VALLEY, Calif., August 19, 2014 -- Bay Area ... to diagnose and simple to cure, applauds new research ... review journal Ticks and Tick-borne Diseases . ... in Northwest California are active throughout the year, making ... conducted by researchers at California Department of Public Health ...
Breaking Biology News(10 mins):Blueprint for next generation of chronic myeloid leukemia treatment 2Lyme disease risk is year-round in Northwest California, according to new study 2Lyme disease risk is year-round in Northwest California, according to new study 3
... Richfield Co. was tasked with cleaning up a major superfund ... Texas A&M University professor, got a call to assist the ... crop science professor, spent two years leading a Texas A&M ... of copper mining, mineral processing and smelting in the Anaconda, ...
... In the first side-by-side tests of a half-dozen palladium- and ... scientists have found that palladium destroys TCE far faster than ... cases. The results will appear in a new study ... B: Environmental. TCE, or trichloroethene, is a widely ...
... 2012: Element Six, the world leader in synthetic ... of Warwick,s Departments of Chemistry and Physics, have ... properties of metal-like boron-doped synthetic diamond. The research ... properties while retaining the full strength and durability ...
Cached Biology News:Mining cleanup benefits from Texas A&M expertise 2Mining cleanup benefits from Texas A&M expertise 3Palladium-gold nanoparticles clean TCE a billion times faster than iron filings 2Synthetic diamond steps closer to next generation of high performance electrochemical applications 2Synthetic diamond steps closer to next generation of high performance electrochemical applications 3
... a group of enzymes involved in matrix ... metalloproteinase family ten exist in soluble form ... MT1-MMP, MT2-MMP, MT3-MMP also known as MMP14, ... domain anchoring them to the cell surface. ...
...
... IKATUBE ULTRA TURRAX Tube Disperser System from IKA ... It offers a cleaner, safer, and more efficient ... sample volumes from 2 to 15 ml inside ... can choose one of 4 different tube types. ...
...
Biology Products: