Navigation Links
UCB's Cimzia(R) (certolizumab pegol), Shows Rapid and Sustained Clinical Response in Adult Patients Living with Moderate to Severe Rheumatoid Arthritis
Date:10/17/2009

were sustained throughout the study. At Week 100, ACR20 response rates were 68.2% and 69.5% in patients who originally received certolizumab pegol 200 mg or 400 mg plus MTX, respectively. ACR50 response rates were 55.2% and 51.5 % respectively. At Week 100, 72.4% and 77.3% of certolizumab pegol 200 mg or 400 mg completers respectively, were mTSS non-progressors, as defined by a change from RAPID 1 baseline in mTSS of less than or equal to 0.05.

(a)ACR (American College of Rheumatology) response scores measure improvement in the tender and swollen joint count and also include assessment of the following five parameters: patient's global assessment, physician's global assessment, patient's assessment of pain, degree of disability, and level of acute-phase reactant. ACR20 is achieved when there is 20% improvement in the tender and swollen joint count as well as a 20% improvement in at least three of the five parameters. ACR50 and ACR70 are an extension of these criteria corresponding to a 50% and 70% improvement respectively.

(b)The modified total Sharp score (mTSS) is a measurement used to assess changes in bone erosion and joint-space narrowing measured by X-ray. A smaller change in mTSS reflects less progression of joint damage.

About CIMZIA®

Cimzia® is the only PEGylated anti-TNF (Tumour Necrosis Factor). Cimzia® has a high affinity for human TNF-alpha, selectively neutralising the pathophysiological effects of TNF-alpha. Over the past decade, TNF-alpha has emerged as a major target of basic research and clinical investigation. This cytokine plays a key role in mediating pathological inflammation, and excess TNF-alpha production has been directly implicated in a wide variety of diseases. The U.S. Food and Drug Administration (FDA) has approved Cimzia® for reducing signs and symptoms of Crohn's disease and maintaining c
'/>"/>

SOURCE UCB
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology technology :

1. Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohns Patients
2. New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohns Patients With Fistulizing Disease
3. FDA Agrees to Review Cimzia(R) File for the Treatment of Rheumatoid Arthritis
4. Tiny test tube experiment shows reaction of melting materials at the nano scale
5. New Survey Shows Devastating Impact of Rheumatoid Arthritis Pain on Intimate Relations
6. Topical erectile dysfunction therapy shows promise
7. Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost
8. Medicagos H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose
9. Video shows nanotube spins as it grows
10. MuGard Data From UK Study Shows Prevention of Oral Mucositis in Head and Neck Cancer Patients
11. Investigational Urine NGAL Biomarker Shows Promise to Monitor Cyclosporine Toxicity in Cardiac Transplant Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... HONG KONG , May 4, 2015 ... or the "Company"), China,s leading ... cell processing and stem cell storage services, today announced ... Holdings Limited ("Golden Meditech"), a Hong Kong ... the Company, has entered into an agreement (the "Agreement") ...
(Date:5/4/2015)... Wheaton, Illinois (PRWEB) May 04, 2015 ... treatment options for patients with arm and hand ... rehabilitation exoskeleton at its Oakbrook Terrace network site. ... foundation, the Armeo®Spring is a highly-regarded treatment option ... In acquiring the Armeo®Spring, Marianjoy becomes one of ...
(Date:5/1/2015)... May 1, 2015 /CNW/ - Softchoice, a leading North American IT ... the proud recipient of two Cisco® Partner Summit Country awards. ... the Year and Security Partner of the Year for ... place this week in Montreal . ... two Cisco partner awards at this year,s conference," said ...
(Date:5/1/2015)... Md. and RESEARCH TRIANGLE PARK, N.C. ... UTHR ) announced today that Roger Jeffs , ... provide an overview and update on the company,s business at ... in Boston, Massachusetts . The ... 3:30 PM Eastern Time, and can be accessed via a ...
Breaking Biology Technology:China Cord Blood Corporation Receives Notice of a Transaction Regarding its 7% Senior Convertible Notes Due 2017 Held by KKR 2China Cord Blood Corporation Receives Notice of a Transaction Regarding its 7% Senior Convertible Notes Due 2017 Held by KKR 3Marianjoy Acquires Armeo®Spring Arm and Hand Rehabilitation Exoskeleton at Oakbrook Terrace Facility 2Softchoice recognized with two Country Awards at Cisco Partner Summit 2015 2
... Wash., March 6 Cardiac Science,Corporation (Nasdaq: ... advanced cardiac diagnosis,resuscitation, rehabilitation, and informatics products, ... its leading product brands (Burdick(R),HeartCentrix(R), Powerheart(R), and ... (Logo: http://www.newscom.com/cgi-bin/prnh/20050913/SFTU139LOGO ), "We believe ...
... March 5 /PRNewswire-FirstCall/ - Dragon Pharmaceutical Inc.,("Dragon" ... BBSE: DRP), a leading,international pharmaceutical company today ... capacity for its core products 7ACA and,Clavulanic ... order to meet increasing,demand from its customers. ...
... Acura,Pharmaceuticals, Inc. (Nasdaq: ACUR ) reported 2007 fourth ... compared to net income,of $3.9 million, or $0.44 loss per ... below) for the same quarter in 2006.,For the year ended ... million, or $0.11 per share compared to a net loss ...
Cached Biology Technology:Cardiac Science Unveils Major Brand Change; Strategy to Lift Brand Awareness 2Cardiac Science Unveils Major Brand Change; Strategy to Lift Brand Awareness 3Cardiac Science Unveils Major Brand Change; Strategy to Lift Brand Awareness 4Dragon announces new product launch; increase in annual production output capacity 2Dragon announces new product launch; increase in annual production output capacity 3Dragon announces new product launch; increase in annual production output capacity 4Acura Pharmaceuticals, Inc. Reports 2007 4th Quarter and Annual Financial Results; Sets 2008 Expectations 2Acura Pharmaceuticals, Inc. Reports 2007 4th Quarter and Annual Financial Results; Sets 2008 Expectations 3Acura Pharmaceuticals, Inc. Reports 2007 4th Quarter and Annual Financial Results; Sets 2008 Expectations 4Acura Pharmaceuticals, Inc. Reports 2007 4th Quarter and Annual Financial Results; Sets 2008 Expectations 5Acura Pharmaceuticals, Inc. Reports 2007 4th Quarter and Annual Financial Results; Sets 2008 Expectations 6
(Date:3/24/2015)... March 24, 2015   NexID Biometrics LLC, ... security-authentication needs, today announced the beginning of shipments of ... The company, based in Potsdam, ... three-day Connect:ID Expo, which began here today at the ... version 2.0 of its SDK boosts the accuracy rate ...
(Date:3/23/2015)... YORK , March 23, 2015   HOYOS ... property management company, today announced that the Company will ... for both enterprise and consumers at Connect:ID on March ... HOYOS Labs will highlight the IEEE Biometric ... TM ; and enterprise access control system. BOPS ...
(Date:3/20/2015)... 2015 Research and Markets ( ... "India Sensors Market Forecast and Opportunities 2020" ... sensor market is projected to grow at a ... electronics, automotive, industrial and healthcare sectors are the ... In addition, adoption of MEMS technology in sensors ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3
... found why women have an edge in keeping a healthier ... - at least before reaching menopause. Premenopausal women are ... in general, but afterward their risks are essentially the same ... Vascular Biology Center at the Medical College of Georgia. ...
... Sciences has awarded Arthur Grossman, of the Carnegie Institution,s ... Medal "in recognition of excellence in published research on ... the Helen P. Smith Fund. Grossman is ... about Chlamydomonas, a tiny green alga affectionately called Chlamy, ...
... This release is available in German . ... year as a result of pneumococcal infection, which causes ... and the elderly are especially at risk. Vaccines are ... and increasing resistance to antibiotics is making treatment more ...
Cached Biology News:Researchers may have found why women have an edge on salt-sensitive hypertension 2Carnegie's Arthur Grossman receives Gilbert Morgan Smith medal 2Deceiving cell walls 2
... The IHC Select Immunoperoxidase Secondary Detection System ... or goat IgG in the Primary Antibody. ... present in the specimen. Any excess antibody ... Antibody Reagent (conjugated to biotin) is added ...
... Protein Purification Protocols covers a wide range ... novice and experienced researchers in all areas ... excerpt from the books preface illustrates just ... your research library., The chapters introduce the ...
... long double stranded RNA (dsRNA) has been ... diverse group of organisms as well as ... to the inhibition of protein expression by ... messenger RNA (mRNA). Attempts to induce RNA ...
... movement counts, similar to an infrared beam break ... subjects at once, in two frames of reference, ... experimental group at once, and allow social interaction ... a variety of other spatial behavior situations, including ...
Biology Products: