Navigation Links
U of A led team makes breakthrough demonstration of pH-regulating protein
Date:12/23/2009

Researchers have identified the protein mechanism that senses bicarbonate fluctuations and adjusts blood pH levels.. A Canadian/U.S. research team led by University of Alberta biological sciences professor, Greg Goss and his graduate students Martin Tresguerres and Scott Parks achieved the first demonstration of the process in a whole animal. The researchers found that the protein adenylyl cyclase sensed and then regulated the pH blood levels in a dogfish shark following feeding.

"Researchers have been trying to see how this process works for 50 years," said Goss. "It opens a whole avenue of possibilities of how we could regulate the blood pH in the human body."

Blood pH, the acidity of blood, is tightly regulated. pH fluctuations throw off the body's metabolism and is related to a wide number of human ailments such a diabetes, kidney disease and male infertility.

The protein adenylyl cyclase senses the bicarbonate (alkaline) level in the blood and triggers cascades of other proteins that enable cellular functions to adjust and maintain an acceptable pH level.

Research is moving forward to better understand the process and its possible implications for human health.


'/>"/>

Contact: Brian Murphy
brian.murphy@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Page: 1

Related biology technology :

1. Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue
2. Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins
3. FDA Advisory Committee Makes Favorable Recommendation for Cervarix, GlaxoSmithKlines Candidate Cervical Cancer Vaccine
4. Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan
5. Provocative New Fiction Makes for a Fascinating, Fast Paced Read
6. What Makes a University Great? Americans Say Renowned Faculty, Top-Rank Research Center are Most Important, According to New Survey from IP Advocate
7. Cardiogenesis Corporation Makes Pre-IDE Submission for PHOENIX Combination Delivery System
8. Practice makes perfect -- motor memory possible for neuroprosthetic control
9. Box maker, Wildcat Wholesale, Makes Cryogenic Freezer Storage Boxes Affordable By Selling Directly To Labs
10. Thomson Reuters Makes Disease Briefing on Influenza Covering H1N1 (Swine Flu) Publicly Available
11. Physician's Organization Makes History by Publishing U.S.'s First Adult Stem Cell Guidelines (ASCTA Drives Safe Stem Cell Practices)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/15/2017)... NY (PRWEB) , ... July 15, 2017 , ... ... over 5 years. During this time, the people at FFS have learned that ... their customers, engineers at FFS are able to launch new products to meet the ...
(Date:7/14/2017)... ... 2017 , ... Dr. Joshua Mondlick has introduced the LANAP® protocol to treat ... Perio, in the Phoenix area. Dr. Mondlick is at the forefront of the ... treatment to re-grow bone and with significantly less pain than traditional surgery options. , ...
(Date:7/14/2017)... USA/ Martinsried, Germany (PRWEB) , ... July 14, ... ... newly developed standardized solution for sample preparation of proteins to clean peptides for ... Diagenode Bioruptor® sonication system. , The PreOmics iST Kit is based on ...
(Date:7/13/2017)... ... July 13, 2017 , ... Heritage Biologics ... URAC is the independent leader in promoting healthcare quality through accreditation, certification and ... quality care, improved processes and better patient outcomes. , ÔÇťAchieving URAC accreditation ...
Breaking Biology Technology:
(Date:4/11/2017)... April 11, 2017 No two people ... at the New York University Tandon School of ... have found that partial similarities between prints are ... in mobile phones and other electronic devices can ... The vulnerability lies in the fact that fingerprint-based ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC , ... that the United States Patent and Trademark Office (USPTO) ... covers the linking of an iris image with a ... and represents the company,s 45 th issued patent. ... is very timely given the multi-modal biometric capabilities that ...
Breaking Biology News(10 mins):