Navigation Links
U of A led team makes breakthrough demonstration of pH-regulating protein
Date:12/23/2009

Researchers have identified the protein mechanism that senses bicarbonate fluctuations and adjusts blood pH levels.. A Canadian/U.S. research team led by University of Alberta biological sciences professor, Greg Goss and his graduate students Martin Tresguerres and Scott Parks achieved the first demonstration of the process in a whole animal. The researchers found that the protein adenylyl cyclase sensed and then regulated the pH blood levels in a dogfish shark following feeding.

"Researchers have been trying to see how this process works for 50 years," said Goss. "It opens a whole avenue of possibilities of how we could regulate the blood pH in the human body."

Blood pH, the acidity of blood, is tightly regulated. pH fluctuations throw off the body's metabolism and is related to a wide number of human ailments such a diabetes, kidney disease and male infertility.

The protein adenylyl cyclase senses the bicarbonate (alkaline) level in the blood and triggers cascades of other proteins that enable cellular functions to adjust and maintain an acceptable pH level.

Research is moving forward to better understand the process and its possible implications for human health.


'/>"/>

Contact: Brian Murphy
brian.murphy@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Page: 1

Related biology technology :

1. Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue
2. Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins
3. FDA Advisory Committee Makes Favorable Recommendation for Cervarix, GlaxoSmithKlines Candidate Cervical Cancer Vaccine
4. Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan
5. Provocative New Fiction Makes for a Fascinating, Fast Paced Read
6. What Makes a University Great? Americans Say Renowned Faculty, Top-Rank Research Center are Most Important, According to New Survey from IP Advocate
7. Cardiogenesis Corporation Makes Pre-IDE Submission for PHOENIX Combination Delivery System
8. Practice makes perfect -- motor memory possible for neuroprosthetic control
9. Box maker, Wildcat Wholesale, Makes Cryogenic Freezer Storage Boxes Affordable By Selling Directly To Labs
10. Thomson Reuters Makes Disease Briefing on Influenza Covering H1N1 (Swine Flu) Publicly Available
11. Physician's Organization Makes History by Publishing U.S.'s First Adult Stem Cell Guidelines (ASCTA Drives Safe Stem Cell Practices)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ANN ARBOR, Mich. , Dec. 7, 2016 ... breakthrough immune modulatory medicines, announced today the initiation of ... therapeutic candidate, LYC-30937- E nteric C oated, in ... disease that is estimated to affect as many as ... , with approximately 1.5 - 3 million cases being ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... ... digital pathology, announced today a new service to enable rapid migration of large ... upload has remained one of the factors limiting adoption of digital pathology. Proscia’s ...
(Date:12/7/2016)... Woods Hole, Massachusetts (PRWEB) , ... December 07, 2016 , ... Kara Dwyer Dodge grew ... 1966, Richard Dwyer, a third-generation fisherman in Scituate, Mass., found a sea turtle entangled in ... to shore, where the turtle became a minor sensation because no one could remember ever ...
(Date:12/6/2016)... ... December 06, 2016 , ... ... privately-held contract pharmaceutical development and manufacturing organisation, today announced the formation ... combining a leading CRO and the industry’s only Contract Commercial Organization (CCO). ...
Breaking Biology Technology:
(Date:11/19/2016)... , Nov. 18, 2016 Securus Technologies, a ... for public safety, investigation, corrections and monitoring, announced today ... competitor, ICSolutions, to have an independent technology judge determine ... most modern high tech/sophisticated telephone calling platform, and the ... that they do most of what we do – ...
(Date:11/15/2016)... , Nov. 15, 2016  Synthetic Biologics, Inc. ... therapeutics focused on the gut microbiome, today announced ... 25,000,000 shares of its common stock and warrants ... at a price to the public of $1.00 ... Synthetic Biologics from the offering, excluding the proceeds, ...
(Date:6/27/2016)... Research and Markets has announced the addition of the ... The report forecasts the biometrics ... a CAGR of 12.28% during the period 2016-2020. ... with inputs from industry experts. The report covers the market landscape ... includes a discussion of the key vendors operating in this market. ...
Breaking Biology News(10 mins):