Navigation Links
U of A led team makes breakthrough demonstration of pH-regulating protein
Date:12/23/2009

Researchers have identified the protein mechanism that senses bicarbonate fluctuations and adjusts blood pH levels.. A Canadian/U.S. research team led by University of Alberta biological sciences professor, Greg Goss and his graduate students Martin Tresguerres and Scott Parks achieved the first demonstration of the process in a whole animal. The researchers found that the protein adenylyl cyclase sensed and then regulated the pH blood levels in a dogfish shark following feeding.

"Researchers have been trying to see how this process works for 50 years," said Goss. "It opens a whole avenue of possibilities of how we could regulate the blood pH in the human body."

Blood pH, the acidity of blood, is tightly regulated. pH fluctuations throw off the body's metabolism and is related to a wide number of human ailments such a diabetes, kidney disease and male infertility.

The protein adenylyl cyclase senses the bicarbonate (alkaline) level in the blood and triggers cascades of other proteins that enable cellular functions to adjust and maintain an acceptable pH level.

Research is moving forward to better understand the process and its possible implications for human health.


'/>"/>

Contact: Brian Murphy
brian.murphy@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Page: 1

Related biology technology :

1. Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue
2. Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins
3. FDA Advisory Committee Makes Favorable Recommendation for Cervarix, GlaxoSmithKlines Candidate Cervical Cancer Vaccine
4. Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan
5. Provocative New Fiction Makes for a Fascinating, Fast Paced Read
6. What Makes a University Great? Americans Say Renowned Faculty, Top-Rank Research Center are Most Important, According to New Survey from IP Advocate
7. Cardiogenesis Corporation Makes Pre-IDE Submission for PHOENIX Combination Delivery System
8. Practice makes perfect -- motor memory possible for neuroprosthetic control
9. Box maker, Wildcat Wholesale, Makes Cryogenic Freezer Storage Boxes Affordable By Selling Directly To Labs
10. Thomson Reuters Makes Disease Briefing on Influenza Covering H1N1 (Swine Flu) Publicly Available
11. Physician's Organization Makes History by Publishing U.S.'s First Adult Stem Cell Guidelines (ASCTA Drives Safe Stem Cell Practices)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... Cancer experts from ... believe could be a new and helpful biomarker for malignant pleural mesothelioma. Surviving ... to read it now. , Biomarkers are components in the blood, tissue ...
(Date:6/27/2016)... ... June 27, 2016 , ... Newly ... technologies, services and solutions to the healthcare market. The company's primary focus is ... manufacturing, sales and marketing strategies that are necessary to help companies efficiently bring ...
(Date:6/27/2016)... PHILADELPHIA , June 27, 2016  Liquid ... today announced the funding of a Sponsored Research ... study circulating tumor cells (CTCs) from cancer patients.  ... changes in CTC levels correlate with clinical outcomes ... therapies. These data will then be employed to ...
(Date:6/24/2016)... on a range of subjects including policies, debt and investment ... Speaking at a lecture to the Canadian Economics ... the country,s inflation target, which is set by both the ... "In certain areas there needs to be frequent ... not sit down and address strategy together?" He ...
Breaking Biology Technology:
(Date:6/2/2016)... LONDON , June 2, 2016 ... has awarded the 44 million US Dollar project, ... Security Embossed Vehicle Plates including Personalization, Enrolment, and IT Infrastructure ... world leader in the production and implementation of Identity Management ... in January, however Decatur was selected ...
(Date:5/20/2016)... , May 20, 2016  VoiceIt is ... partnership with VoicePass. By working together, ... experience.  Because VoiceIt and VoicePass take slightly different ... engines increases both security and usability. ... excitement about this new partnership. "This ...
(Date:4/28/2016)... and BANGALORE, India , April 28, 2016 ... a product subsidiary of Infosys (NYSE: INFY ), ... a global partnership that will provide end customers ... mobile banking and payment services.      (Logo: ... innovation area for financial services, but it also plays a ...
Breaking Biology News(10 mins):