Navigation Links
U of A led team makes breakthrough demonstration of pH-regulating protein
Date:12/23/2009

Researchers have identified the protein mechanism that senses bicarbonate fluctuations and adjusts blood pH levels.. A Canadian/U.S. research team led by University of Alberta biological sciences professor, Greg Goss and his graduate students Martin Tresguerres and Scott Parks achieved the first demonstration of the process in a whole animal. The researchers found that the protein adenylyl cyclase sensed and then regulated the pH blood levels in a dogfish shark following feeding.

"Researchers have been trying to see how this process works for 50 years," said Goss. "It opens a whole avenue of possibilities of how we could regulate the blood pH in the human body."

Blood pH, the acidity of blood, is tightly regulated. pH fluctuations throw off the body's metabolism and is related to a wide number of human ailments such a diabetes, kidney disease and male infertility.

The protein adenylyl cyclase senses the bicarbonate (alkaline) level in the blood and triggers cascades of other proteins that enable cellular functions to adjust and maintain an acceptable pH level.

Research is moving forward to better understand the process and its possible implications for human health.


'/>"/>

Contact: Brian Murphy
brian.murphy@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Page: 1

Related biology technology :

1. Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue
2. Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins
3. FDA Advisory Committee Makes Favorable Recommendation for Cervarix, GlaxoSmithKlines Candidate Cervical Cancer Vaccine
4. Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan
5. Provocative New Fiction Makes for a Fascinating, Fast Paced Read
6. What Makes a University Great? Americans Say Renowned Faculty, Top-Rank Research Center are Most Important, According to New Survey from IP Advocate
7. Cardiogenesis Corporation Makes Pre-IDE Submission for PHOENIX Combination Delivery System
8. Practice makes perfect -- motor memory possible for neuroprosthetic control
9. Box maker, Wildcat Wholesale, Makes Cryogenic Freezer Storage Boxes Affordable By Selling Directly To Labs
10. Thomson Reuters Makes Disease Briefing on Influenza Covering H1N1 (Swine Flu) Publicly Available
11. Physician's Organization Makes History by Publishing U.S.'s First Adult Stem Cell Guidelines (ASCTA Drives Safe Stem Cell Practices)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... May 23, 2016 - Leading CRO,s Use ... - Frontage Implement a Single Platform to Manage End-to-end Operations ... Within the Bioanalytical lab Frontage Laboratories, a full-service contract ... and China , has selected IDBS, ... In addition to serving as the global electronic lab notebook (ELN), ...
(Date:5/20/2016)... ... 20, 2016 , ... The leading Regenerative Veterinary Medicine Company, VetStem Biopharma ... treated over 100 of their own patients with the VetStem Cell Therapy. Each of ... care for their patients. , The veterinarians are Dr Ross Rich former owner ...
(Date:5/19/2016)... ... , ... Anton Paar USA, located in Ashland, Virginia is pleased to announce ... structure adds a third office building to the current facilities. , Growth is ... land, along with office space adjacent to the previous main building. Through remodels and ...
(Date:5/19/2016)... Regen BioPharma, Inc ... announced today initiation of a preclinical development program ... cancer immunotherapeutic product leveraging its NR2F6 immunological checkpoint. ... generation of cord blood derived killer cells whose ... product in development will be a "universal donor" ...
Breaking Biology Technology:
(Date:5/3/2016)...  Neurotechnology, a provider of high-precision biometric identification ... Identification System (ABIS) , a complete system for ... can process multiple complex biometric transactions with high ... face or iris biometrics. It leverages the core ... MegaMatcher Accelerator , which have been used in ...
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
Breaking Biology News(10 mins):