Navigation Links
U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)
Date:11/20/2007

Ph.D., Executive Vice President, Chief Scientific Officer and President, Research and Development, Bristol-Myers Squibb. "This approval is a reflection of our ongoing commitment to provide innovative therapies, such as ABILIFY, to help adults living with depression."

"We are pleased that ABILIFY has achieved this important milestone as the first medication approved as adjunctive treatment for adults with major depressive disorder," said Taro Iwamoto, Ph.D., Chief Executive Officer, President and Chief Operating Officer, Otsuka Pharmaceutical Development and Commercialization, Inc. "This new add-on treatment option for depression represents hope for many adults suffering from this debilitating illness."

Major depressive disorder affects millions of U.S. adults at some point in their lives.(2) A recent study evaluated different treatment approaches, including adjunctive medications and switching strategies, in patients with MDD.(1) The study found that 63 percent of patients did not achieve adequate relief of depressive symptoms following the initial treatment with an antidepressant alone.(1) Additionally, the study demonstrated that the use of adjunctive medications in treatment may be useful to improve unresolved depressive symptoms.(1)

Clinical Trial Design and Findings

Two six-week, double-blind, randomized, placebo-controlled, multicenter studies evaluated the efficacy and safety of add-on ABILIFY in adult patients with a primary diagnosis of major depressive disorder who had experienced an inadequate response to prior antidepressant therapy (one to three courses) in the current episode.

After an eight-week prospective treatment phase with one ADT plus single- blind placebo to confirm inadequate response to ADT, 743 participants entered a six-week randomized treatment phase during which they continued their ADT plus double-blind adjunctive placebo or adjunctive ABILIFY. All study participants received one of the commonly prescribed
'/>"/>

SOURCE Bristol-Myers Squibb Company and Otsuka PharmaceuticalCo., Ltd.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Baxter and Halozyme Announce Collaboration for Development of Subcutaneous GAMMAGARD LIQUID(TM) Administration Using Enhanze(TM) Technology
2. Bioscrypts V-Station MIFARE Placed on Transportation Security Administrations Qualified Products List
3. Australian Therapeutics Goods Administration Approval for ActiPatch Achieved
4. FDA Approves Administration of LEXIVA(R) with Lower Dose of Boosting Medication Ritonavir
5. Korean Food and Drug Administration Approval for ActiPatch Achieved
6. Brazilian National Biosafety Technical Committee Approves Monsanto Company Insect-Protected Corn Trait
7. FDA Approves RISPERDAL(R) to Treat Adolescents with Schizophrenia and Children and Adolescents with Bipolar Mania
8. FDA Approves ACAM2000(TM) Vaccine for Protection Against Smallpox
9. NJ Board of Pharmacy Approves Wedgewood Pharmacy Technician-Training Program
10. FDA Approves Expanded Labeling for Campath(R) to Include First-line Treatment for Leading Form of Adult Leukemia
11. FDA Approves New 300mg Loading Dose Tablet for PLAVIX(R) (clopidogrel bisulfate)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2015)... PA (PRWEB) April 28, 2015 ... participation in the upcoming Labroots virtual event, ... 13-14, 2015. The theme of this conference ... topics such as RNAi, Next-generation sequencing, cancer ... mapping, exomes, genomic medicine, human Genome structural ...
(Date:4/28/2015)... 2015 USDM Life Sciences , ... sciences industry, is proud to partner with Salesforce.com to ... GxP Processes to the Cloud . , Numerous medium ... potential and power of moving their GxP processes to ... data in a cloud environment, such as Salesforce is ...
(Date:4/28/2015)... 2015  Adaptive Biotechnologies today announced the recent ... The University of Texas MD Anderson Cancer Center ... identification and quantification of populations of B cells ... of people with classical Hodgkin,s lymphoma (CHL). The ... Haematology , represent a first step toward developing ...
(Date:4/28/2015)... April 28, 2015 CIRTEC ... device manufacturing services for complex Class III ... announced plans to develop a new 35,000 sq. ... , CIRTEC has a long history of working ... to usher breakthrough neurostimulation, heart assistance, drug delivery ...
Breaking Biology Technology:Pittcon Announces Plans to Exhibit at the Annual Labroots Genetics and Genomics Virtual Event 2Pittcon Announces Plans to Exhibit at the Annual Labroots Genetics and Genomics Virtual Event 3USDM Life Sciences Partners with Salesforce.com for Webinar on How Life Sciences Organizations Can Move GxP Processes to the Cloud 2Adaptive Biotechnologies and Researchers from MD Anderson Cancer Center Demonstrate Ability to Detect Hodgkin's Lymphoma in Blood 2Adaptive Biotechnologies and Researchers from MD Anderson Cancer Center Demonstrate Ability to Detect Hodgkin's Lymphoma in Blood 3CIRTEC Medical Systems Expands Capacity with New Advanced Manufacturing Facility 2
... (Nasdaq: GPRO ) announced today that it ... of credit to finance its pending acquisition of Tepnel ... its existing share repurchase program.The Company will pay interest ... by Bank of America, at a floating rate 0.6 ...
... As Part of "In the Zone for UC" Campaign, ... Crohn,s & Colitis Foundation of America for Each Point ... Centocor Ortho Biotech Inc. announced today a partnership ... of ulcerative colitis (UC) and funding to support continued ...
... to resume manufacturing at KV facilitiesST. LOUIS, March 2 ... it has entered into a consent decree with the ... drug manufacturing and distribution. The decree provides a ... to resume the manufacture and distribution of products marketed ...
Cached Biology Technology:Gen-Probe Borrows $170 Million Under New Line of Credit 2Pro Hockey Player Fernando Pisani Looks to Shoot and Score Against Ulcerative Colitis 2Pro Hockey Player Fernando Pisani Looks to Shoot and Score Against Ulcerative Colitis 3Pro Hockey Player Fernando Pisani Looks to Shoot and Score Against Ulcerative Colitis 4KV Pharmaceutical Enters Into Consent Decree With FDA 2KV Pharmaceutical Enters Into Consent Decree With FDA 3KV Pharmaceutical Enters Into Consent Decree With FDA 4KV Pharmaceutical Enters Into Consent Decree With FDA 5KV Pharmaceutical Enters Into Consent Decree With FDA 6
(Date:4/21/2015)... High crime rate, increasing ... access control systems market in Saudi Arabia ... published report by TechSci Research " Saudi Arabia Access Control ... systems market in Saudi Arabia ... control systems market in the Kingdom is growing at ...
(Date:4/14/2015)... Conn. , April 14, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... been nominated for the 2015 New York Design Awards ... The Design100, New York City Design Awards are part ... based on over 2,500 ratings from the marketplace, industry ...
(Date:4/8/2015)... 2015  Infinisource, a leading provider of SaaS-based Human ... a leading supplier of biometric identification and security ... most advanced biometrically-enabled time clock, the companies announced ... is setting a bold, new standard for the ... small and mid-size employer. When connected to the ...
Breaking Biology News(10 mins):Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3
... An international team of scientists has published a new ... extinct, natural habitats become less productive and contain fewer total ... that humans get from nature. The article ... of the National Academy of Sciences the week of Nov. ...
... in an expanded access program for sapropterin dihydrochloride, ... a rare genetic metabolic disorder that, if left ... severe mental retardation. Currently, there are eight patients ... Childrens. Under an expanded access program, the ...
... Children who possess a gene known to increase the ... cognitive function, an Oregon Health & Science University study ... of Medicine discovered that 7- to 10-year-olds with a ... nerve cell regeneration and neuroprotection display reduced spatial learning ...
Cached Biology News:Scientists warn that species extinction could reduce productivity of plants on Earth by half 2Nationwide Children's Hospital involved in expanded access program for treatment of PKU 2Children with gene show reduced cognitive function 2
... Precision-designed for Optimal Microdissection , CapSure ... the precise and rapid extraction of populations ... cytology samples with Laser Capture Microdissection., ... Downstream Molecular Analysis , All CapSure LCM ...
... ChipReader systems are highly sensitive laser confocal ... These are advanced scanners that meet your ... background level, and optimizing the signal on ... end of the range for increased sensitivity. ...
... on four slides. The new ArraySlide 24-4 ... (6mm x 7mm) individual printing surfaces for ... analysis studies. Unlike other systems, this device ... presence of contaminating adhesives. The chamber itself ...
... : GeneTraffic is built to be a ... GeneTraffic provides visual and computational tools to ... to analysis. , Data and Project ... the MIAME (Minimum Information About a Microarray ...
Biology Products: