Navigation Links
Trigemina Receives ISP Approval of Clinical Study Protocol for TI-001 Phase 2 Trial
Date:4/8/2013

MORAGA, Calif., April 8, 2013 /PRNewswire/ -- Trigemina, Inc., a biopharmaceutical company focused on the discovery and development of non-narcotic, nasally delivered, analgesic drug products, today announced that the Instituto de Salud Publica (ISP) of Chile has approved the Company's protocol for its Phase 2 clinical study of TI-001, intranasal oxytocin, for the treatment of chronic migraine. The TRIG-05 study is expected to begin enrollment in April, 2013, with a primary clinical endpoint of demonstrating efficacy, tolerability and safety of TI-001.

"The ISP acceptance of our study protocol is an important step forward for the clinical development of TI-001 in chronic migraine patients," said Charles Yeomans , Chief Executive Officer of Trigemina. "TI-001 demonstrated strong efficacy in our preclinical and pilot human studies, especially for such a difficult to treat condition as chronic migraine. With approval from the ISP of Chile, we are confident that we will be able to move forward with our business development goals for 2013 as planned."

In preclinical and human pilot studies, treatment with TI-001 has shown promising results for use as a safe and effective therapy for all forms of chronic and subacute head pain. In one study, 64% of chronic migraine patients receiving TI-001 improved from severe to mild/no pain or from moderate to no pain, whereas only 28% of patients receiving placebo reported improvement. Importantly, 29% of patients receiving TI-001 improved to zero pain, compared to none of the placebo treated patients, suggesting strong efficacy for the therapy with little to no side effects and no risk of developing addiction.

"The unique science underlying TI-001's robust efficacy and lack of abuse potential is the relationship shared between pain and oxytocin," stated David C. Yeomans , Ph
'/>"/>

SOURCE Trigemina, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. UCSB professor receives award for graphene electronics research
2. Watsons Generic Yaz(R) Receives FDA Approval
3. Quanterix Receives Funding From the Department of Homeland Security to Develop Test for Botulinum Toxin
4. Life Technologies Ion Personal Genome Machine Receives San Diegos CONNECT Most Innovative New Product Award
5. MacroGenics Receives Milestone Payment as Part of Its Global DARTâ„¢ Alliance with Boehringer Ingelheim
6. Intimate Bridge 2 Conception, Inc. Receives $4.3M
7. Pacific Meso Center Receives Generous Donation to First Free-Standing Mesothelioma Research Laboratory in Los Angeles
8. BioNeutral Group Receives $400,000 in Equity Financing
9. Amsterdam Molecular Therapeutics Receives US Orphan Designation for Hemophilia B Gene Therapy
10. Arcion Receives Notice of Allowance for US Patent for Novel Topical Lidocaine Formulation for Pain
11. Life Technologies Receives AFNOR Validation for Tests Designed to Detect Listeria Contamination in Food Samples
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2014)... 2014 ResearchMoz presents this ... USA Cancer Biomaker Market to 2018 ... ResearchMoz presents this most up-to-date research on Global ... Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, ... GLOBAL & USA ...
(Date:7/20/2014)... fuel gets recycled, the process releases radioactive krypton and ... with the related gas radon. A new porous material ... July 20 in Nature Materials shows how: ... not out. , The CC3 material could be ... nuclear fuel or air in buildings and also in ...
(Date:7/19/2014)... 2014 United States Non-Vascular Stents ... new report, "United States Non-Vascular Stents Market Outlook ... United States Non-Vascular Stents market. The report provides ... units) and average prices (in US dollars) within ... and Metal Biliary Stents (Metal Non-Covered Biliary Stents, ...
(Date:7/18/2014)... 18, 2014  Neogen Corporation (Nasdaq: NEOG ... chief operating officer and president, has resigned, effective July ... a consultant going forward on special projects. His resignation ... in this position since September 2013. On an interim ... Herbert , who has been Neogen,s chief executive officer ...
Breaking Biology Technology:Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 2Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 3Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 4Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 5Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 6A noble gas cage 2A noble gas cage 3United States Non-Vascular Stents Market Outlook to 2020 | Researchmoz 2United States Non-Vascular Stents Market Outlook to 2020 | Researchmoz 3United States Non-Vascular Stents Market Outlook to 2020 | Researchmoz 4
... If you have a creative idea or invention, or you ... want to protect, the first thing you do is contact ... that you have protected your invention, so you're set, right? ... sage advice: look both ways before you cross the street, ...
... a private research center south of Madison, a group ... to talk about the ethical choices presented by biotechnology's ... forum will be the memory of Terri Schiavo. , ... questions surrounding patients such as Schiavo, the brain-damaged Florida ...
... seems like there's always one person in a crowd who ... obituaries. Not me. I'm compulsive about reading the job classifieds. ... to fathom the difference between the ubiquitous "excellent communication skills" ... them a quick scan every day, even if it happens ...
Cached Biology Technology:Five patent tips for start-up companies 2Five patent tips for start-up companies 3Schiavo's death calls attention to ethical issues weighed at Bioethics Forum 2Schiavo's death calls attention to ethical issues weighed at Bioethics Forum 3Is IT leadership a position or an attitude? 2Is IT leadership a position or an attitude? 3
(Date:7/21/2014)... A team of University of California, Riverside Bourns ... placed under the grates of a backyard grill reduces by ... cooking. , The one-eighth inch thick steel carbon plate with ... by cutting a slit into the grill to allow the ... be adopted by grill manufacturers who could sell new grills ...
(Date:7/21/2014)... at the INRS nergie Matriaux Tlcommunications Research Centre ... and temporal resolution greatly exceeding that obtained to ... laser source to shoot a molecular movie of ... article presenting the advancement was recently published in ... , "The approach we developed combines multiphoton ionization ...
(Date:7/21/2014)... meat contributes to climate change, due to greenhouse gasses ... are on the rise and that beef cattle are ... types of animals. It is published by Climactic ... gas when it comes to climate change. It is ... the greatest portion of greenhouse gas totals. But methane ...
Breaking Biology News(10 mins):Catching grease to cut grill pollution 2Climate: Meat turns up the heat 2
... This press release is available in Spanish . ... del Mar) have proven that the absence of the 14-3-3 ... these cells, capacity to activate the signalling of a protein ... activation of NF-kB in tumours was also identified as the ...
... Biochemists at the University of California, Riverside report a new ... twins and even triplets in plant seeds. Daniel ... an associate research biochemist in the Department of Biochemistry ... a naturally occurring enzyme that recycles vitamin C in plants ...
... Calif. The University of California, Riverside is hosting the ... through June 22, 2012. Held this year at the ... oral presentations and 130 poster presentations. Because research papers on ... the rate of more than 2000 per year, the workshop, which ...
Cached Biology News:A new indicator for breast cancer relapse identified 2Link between vitamin C and twins can increase seed production in crops 2Link between vitamin C and twins can increase seed production in crops 315th Vitamin D Workshop begins tomorrow 215th Vitamin D Workshop begins tomorrow 3
...
Recombinant Rat Leptin, CF...
Adhesive seal-tab, for HybriWell™ hybridization sealing system *set of 400*...
... The CultureWell cell culture systems provide ... cells for staining and imaging. Each ... with standard optical-quality coverslips in cell ... provided sterile and ready to use. ...
Biology Products: