Navigation Links
Triangles guide the way for live neural circuits in a dish
Date:7/19/2012

Korean scientists have used tiny stars, squares and triangles as a toolkit to create live neural circuits in a dish.

They hope the shapes can be used to create a reproducible neural circuit model that could be used for learning and memory studies as well as drug screening applications; the shapes could also be integrated into the latest neural tissue scaffolds to aid the regeneration of neurons at injured sites in the body, such as the spinal cord.

Published today, 20 July, in IOP Publishing's Journal of Neural Engineering, the study, by researchers at the Korea Advanced Institute of Science and Technology (KAIST), found that triangles were the most effective shape for helping to facilitate the growth of axons and guide them onto specific paths to form a complete circuit.

Co-author of the study, Professor Yoonkey Nam, said: "Eventually, we want to know if we can design a neural tissue model that biologically mimics some neural circuits in our brain."

A neuron is an electrically excitable cell that processes and transmits information around the body. The neuron is composed of three main parts: a cell body, or soma, dendrites and an axon, which extends from the soma and links to other cells, creating a network.

When axons grow they are usually guided by proteins. Many researchers have been trying to re-create this key process in a dish by manipulating nerve cells from rat brains.

As nerve cells are usually just a few tens of micrometres in size, the challenge associated with creating a live neural network is firstly positioning cells in desired locations and, secondly, making connections between these cells by guiding the axons in designated directions.

The researchers investigated whether two star shapes, five regular shapes (square, circle, triangle, pentagon and hexagon) and three different sizes of isosceles triangles could guide axons in designated directions. Each shape was the size o
'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
44-117-930-1032
Institute of Physics
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Researchers love triangles
2. JBT Corporation and Swisslog Enter Into Partnership for Automated Guided Vehicles
3. The ABC Clinical Guide to Herbs Now Available Online
4. Neuralstem ALS Stem Cell Trial Featured on Fox Atlanta
5. Neuralstem President and CEO to Update Ongoing ALS and NSI-189/Major Depressive Disorder Trials at 2012 Biotech Showcase
6. Neuralstem President and CEO to Present at BIO CEO & Investor Conference 2012
7. Neuralstem Announces Closing of $5.2-Million Registered Direct Offering
8. Fourteenth Patient Dosed in Neuralstem ALS Stem Cell Trial
9. Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London
10. UCLA researchers demonstrate fully printed carbon nanotube transistor circuits for displays
11. Researchers develop one of the worlds smallest electronic circuits
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... HIGHLIGHTS:Q2 2015 Results (all changes ... Reported sales were $697 million compared to $701 million ... by 8%, and changes in foreign currency exchange rates ... 1%. , By business unit, organic sales growth ... in SAFC Commercial. , Reported diluted EPS was ...
(Date:7/30/2015)... ... July 30, 2015 , ... GEA's Pony™ NS2006L ... operation up to 1500 bar. The sanitary design gauge of the NS2006L is ... , The Pony™ NS2006L homogenizer is an ideal solution for the processing of ...
(Date:7/29/2015)... , July 30, 2015 According ... Market - Growth, Trends & Forecasts (2015-2020), , published by ... US$ 30.25 billion by the end of 2020, with ... accounting for more than 40% of the global market size. ... at a CAGR of 13.7% during the period of (2015-2020). ...
(Date:7/29/2015)... - BioAmber Inc. (NYSE: BIOA ) today announced that ... has resigned.  The Company has hired Andrew Ashworth ... December 2014, as full time interim CFO and has ... Andy Ashworth began his employment today, to ... Andy was the Company,s CFO from September 2011 to ...
Breaking Biology Technology:Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 2Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 3Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 4Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 5Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 6Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 7Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 8Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 9Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 10Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 11Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 12Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 13Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 14Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 15Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 16Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 17Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 18Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 19Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 20GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 2Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 3BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3
... have demonstrated that nanoparticles of cerium oxide -- common diesel ... engines -- can travel from the lungs to the liver ... The data in the study by Dr. Eric R. ... indicate there is a dose-dependent increase in the concentration of ...
... 17, 2011 Funds Will be ... Diagnostics System Designed to Drive the Widespread Adoption ... the Fight Against Infectious Disease Biocartis, ... (MDx) systems designed to drive the widespread adoption ...
... 17, 2011 SeraCare Life Sciences, Inc. (NASDAQ: ... vital products and services to facilitate the discovery, development ... financial results for its 2011 fiscal fourth quarter and ... "During the fourth quarter, we drove an ...
Cached Biology Technology:Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver 2Biocartis Completes EUR 71 Million (USD 100 Million) Series C Fund Raising 2Biocartis Completes EUR 71 Million (USD 100 Million) Series C Fund Raising 3Biocartis Completes EUR 71 Million (USD 100 Million) Series C Fund Raising 4SeraCare Reports Fiscal Year 2011 and Fourth Quarter Financial Results 2SeraCare Reports Fiscal Year 2011 and Fourth Quarter Financial Results 3SeraCare Reports Fiscal Year 2011 and Fourth Quarter Financial Results 4SeraCare Reports Fiscal Year 2011 and Fourth Quarter Financial Results 5SeraCare Reports Fiscal Year 2011 and Fourth Quarter Financial Results 6
(Date:7/23/2015)... , July 23, 2015 Research and ... of the "Global Outlook of the Biometrics ... The global biometrics market is ... and commercial applications owing to the uptake of ... a transformation that enhances the growth of biometrics ...
(Date:7/21/2015)... 2015 Passwords have proven futile for ... recent U.S. Office of Personnel Management breach. Biometric ... conundrum, but developers and end-users are concerned about ... dilemma, Biometrics-as-a-Service provider HYPR Corp. announced today the ... third party integration. A video ...
(Date:7/13/2015)... Conn. , Jul. 13, 2015 NXT-ID, ... "Company"), a biometric authentication company focused on the ... has filed provisional patent 62/188684 for ... achieves another new convenient and secure method to ... new, innovative payment methods, introduced with its groundbreaking ...
Breaking Biology News(10 mins):Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4NXT-ID Patents Behavior-Directed Payments 2NXT-ID Patents Behavior-Directed Payments 3NXT-ID Patents Behavior-Directed Payments 4
... by researchers at the European Centre for the Environment and ... Medicine and Dentistry) and the University of Birmingham has compared ... and concluded that the development of accurate simulations are likely ... because of infirmity or other limitations: but virtual worlds ...
... share about 95 percent of their genes, and mice ... model for studying human biology and disease. But, says ... even more "now that we really know what a ... Fernando Pardo-Manuel de Villena, Ph.D., of the University of ...
... or cod caught in the North Sea but declared as ... of fraud in the fisheries sector. A European Commission report ... genomics, chemistry and forensics - can provide clear answers to ... from.where was this fish caught.is it wild or farmed?". The ...
Cached Biology News:Virtual natural environments and benefits to health 2Virtual natural environments and benefits to health 3Virtual natural environments and benefits to health 4What is a laboratory mouse? Jackson, UNC researchers reveal the details 2What is a laboratory mouse? Jackson, UNC researchers reveal the details 3What fish is on your plate? 2
Use the DUALmembrane kit 3 to carry out DUALmembrane interaction analysis and cDNA library screening to characterize interactions between integral membrane proteins and to identify novel interaction ...
... Waterproof, moisture-proof film prevents sample evaporation, ... folded repeatedly and twisted around sharp ... 21C (70F), wrapping film increases approximately ... film only partially returns to original ...
PlusOne EDTA, disodium salt, 100 g. Category: Electrophoresis Systems & Standards & Reagents, Electrophoresis Standards and Reagents, Buffers....
...
Biology Products: