Navigation Links
TriLink Awarded SBIR Phase I Grant: Thermally Activatable Probes and Cofactors for Hot Start Ligase Chain Reaction
Date:3/15/2011

SAN DIEGO, March 15, 2011 /PRNewswire/ -- TriLink BioTechnologies, Inc. (TriLink) was recently awarded a Phase I SBIR Grant of approximately $100,000 by the National Institutes of Health to develop a Hot Start approach for Ligase Chain Reaction (LCR). Hot Start LCR will employ chemically modified ligation components containing thermolabile protecting groups to eliminate common performance problems seen in LCR, such as false-positive signals and non-specificity. TriLink hopes to find similar benefits as those found in development of their Hot Start primers and dNTPs. If successful, this approach could allow LCR to replace applications where traditional PCR, Gap-LCR and PCR/ligation combination approaches are too expensive, not applicable or problematic. This is the fifth Phase I grant TriLink has been awarded, and it will be funded through July 2011.

"We are excited to have the opportunity to test our proven Hot Start approach on an application with the potential to capture a significant portion of the PCR market," remarked Dr. Alexandre Lebedev, Senior Principal Scientist.

"Moving into LCR is a natural progression for TriLink. While developing our successful CleanAmp™ PCR products and our ongoing ligation work, we gained a unique perspective on the limitations of LCR, and the technical knowledge to solve them," stated TriLink's President and CEO, Richard Hogrefe.

About TriLink

TriLink manufactures custom oligonucleotides, modified nucleoside triphosphates and CleanAmp™ PCR products for the research, diagnostic and OEM markets. In addition, custom chemistry, contract research services and ISO/QSR compliant cGMP production facilities are offered.  TriLink's solutions help advance drug discovery and biomedical research.  Founded in 1996, TriLink is a privately held firm based in San Diego, California and employs approximately 85 scientists and other professionals. For more information about the firm and produ
'/>"/>

SOURCE TriLink BioTechnologies, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. TriLink BioTechnologies Launches CleanAmp™ 7-deaza-dGTP for GC-rich Target Amplification
2. TriLink BioTechnologies to Sponsor Take Me Out to the Ballgame, a SAY San Diego Event Benefiting San Diego Families in Need
3. TriLink BioTechnologies, Inc. Launches New Website and OligoBuilder(R)
4. TriLink BioTechnologies, Inc. Relaunches Oligonucleotide Radiolabeling Services
5. TriLink BioTechnologies to Sponsor GIVING HUNGER THE BLUES, a Benefit Concert to Help Alleviate Hunger in San Diego County
6. 6th Annual Szent-Gyorgyi Prize for Progress in Cancer Research Awarded to Beatrice Mintz, Ph.D.
7. Chimerix Awarded BARDA Contract for Advanced Development of Broad Spectrum Antiviral CMX001 as Medical Countermeasure Against Smallpox
8. Omni Bio Pharmaceutical Awarded Patent for Preventing Anthrax Infection
9. Exagen Diagnostics Awarded $400,000 in Grants Under the QTDP Program
10. Georgia Techs Walt de Heer awarded Materials Research Society Medal
11. Sigma® Life Science Awarded Silver in Top Ten Innovations 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... ... August 27, 2015 , ... Inc. Magazine released its annual list ... as number 1,361 in growth for the three years through 2014. Being named to ... privately held organizations in the country. , “We are thrilled to make the ...
(Date:8/27/2015)... TRIANGLE PARK, N.C. , Aug. 27, 2015 ... on the decision by FedEx, UPS and The ... of certain biological specimens classified as ,select agents, ... and long history of handling these sensitive shipments. ... knowledge of global transportation regulations, trained and certified ...
(Date:8/26/2015)... (PRWEB) , ... August 26, 2015 , ... ... Solutions, announces today that a second US laboratory is to open in Manhattan, ... with the continued partnership and long-term growth of research and development through collaboration ...
(Date:8/26/2015)... -- Roka Bioscience, Inc. (NASDAQ: ROKA ), a molecular ... the detection of foodborne pathogens, today announced that Paul ... Company Emerging Growth Conference on September 2 at 9:20am ... York Marriott Marquis. A live webcast ... relations section of Roka Bioscience,s website at http://rokabio.investorroom.com/ ...
Breaking Biology Technology:iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3Marken Ensures Safe Transportation Of Select Agents And Toxins 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 3
... hit universities and colleges across the country, including ... copyright infringement of both movies and music over ... several cease-and-desist notices to the Universirty of Wisconsin- ... were hosting movie downloads with content that belonged ...
... the information age similar to what the business world ... productivity of our staff, reduce costs, and improve our ... considerable engineering effort that requires hospital officials to look ... can embrace the changes that will improve healthcare. , ...
... Wisconsin has been a leader both in cutting-edge health ... nations leading research universities in UW-Madison, and leading-edge medical ... poised to lead again as the two fields merge ... engineering have long contributed to health care by providing ...
Cached Biology Technology:File Swapping: Download at your own Risk 2File Swapping: Download at your own Risk 3Im Still Waiting for the Information Age in Healthcare 2Im Still Waiting for the Information Age in Healthcare 3The Role of Engineering in Health Science and Technology 2The Role of Engineering in Health Science and Technology 3
(Date:8/17/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market and creator of the Wocket® ... 2015. The new marketing campaign is being spearheaded by ... Group ( http://amplitudemarketing.com/ ) and TPMG ( http://tmpg.com/ ). ... retail driven marketing and brand awareness and has a ...
(Date:8/12/2015)... 2015 As the digital payment ... and advanced biometrics technology is accelerating beyond expectations.  While ... on using their credit cards, the digital currency, mobile ... payment services led by companies in the space such ... Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ...
(Date:8/12/2015)... SAN JOSE, Calif. , Aug. 12, 2015 ... leading developer of human interface solutions, today announced ... the recently announced Match-in-Sensor solution, have officially been ... (FIDO) Alliance. As part of the certification, Synaptics, ... the FIDO 1.0 Universal Authentication Framework (UAF) standard ...
Breaking Biology News(10 mins):NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 2NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3
... team has found a new gene associated with the brain ... a rare form of epilepsy, the study results could help ... findings, which involved nearly two dozen institutions from six different ... American Journal of Human Genetics . In epilepsy, nerve ...
... do poppies and sunflowers grow as a single flower ... has several branches, each carrying flowers? In a new ... access journal PLoS Biology , Dr. Zachary Lippman ... pattern of flower growth in the Solanaceae (nightshade) family ...
... recognized climate scientist and economist Jae Edmonds will speak ... and sequestration in climate stabilization in the plenary opening ... Technologies. He is one of nearly a dozen scientists ... who will present new findings and insights to the ...
Cached Biology News:International team discovers gene associated with epilepsy 2A big bunch of tomatoes? 2PNNL leadership in carbon sequestration featured at international conference 2
... The Biometra TProfessional Thermocycler combines top ... silver block achieves high speed and unparalleled ... graphical display providing programming in a spreadsheet ... High Performance Smart Lid opens on the ...
...
... Kit is an advanced system for isolating DNA from ... be used directly for any downstream application. ... to use in 56 minutes Low melting point ... and TBE gels No specialised equipment required ...
... Columns provide a rapid and simple method for ... to 10 kb) from stained agarose gels or ... from an agarose gel and loaded into the ... column are a series of membranes and filters ...
Biology Products: