Navigation Links
Transgenomic Introduces SURVEYOR(R) Endonuclease Adaptor-Ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation
Date:6/17/2008

Officer and President of Transgenomic commented, "We expect SEAL to have a significant impact on the use of DNA sequencing within pharmacogenomic assessments for personalized medicine. A whole genome catalog of sequence variations below $10,000 is a realistic goal based on our prediction that SEAL should identify point mutations and small insertion/deletions at 100 to 1000 times lower sequencing intensity than current methods."

About SEAL

SURVEYOR Endonuclease Adaptor-ligated Libraries (SEAL) is a cost-effective and high throughput enabling technology for whole genome analysis under development by Transgenomic. It identifies DNA variations between a reference genome and a test genome. Using a linker that attaches an identification tag of known sequence to the ends cleaved by the SURVEYOR Nuclease, SEAL generates a library of genetic variations present within a DNA sample relative to a reference sample, allowing recognition of both the sequence of the variant nucleotide and the sequence context of the mutation. The library can be sequenced directly via standard or massively parallel systems, queried at any desired genetic locus by PCR amplification or archived for subsequent multi-query analysis.

About SURVEYOR

SURVEYOR Mutation Detection Kits and the SURVEYOR Check-It Kit provide reagents and protocols for the detection of mutations in DNA. All of these kits are based on the use of SURVEYOR Nuclease, a mismatch-specific endonuclease shown to recognize and cleave all types of mismatches arising from the presence of single nucleotide polymorphisms (SNPs) or from small insertions or deletions. The protocol is based on the generation of PCR products that are subsequently hybridized to generate mismatches in heteroduplexed DNA which is then treated and cleaved by SURVEYOR Nuclease. SURVEYOR Nuclease can detect genetic variations in samples with high sensitivity.

About Transgenomic

Transgenomic (OTC Bulletin Board: TBIO) is a glob
'/>"/>

SOURCE Transgenomic
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Webcast Alert: Transgenomic Inc. Announces First Quarter 2008 Earnings Release Conference Call Webcast
2. Transgenomic Opens Pharmacogenomics Laboratory in China
3. Reminder Webcast Alert: Transgenomic Inc. Announces Fourth Quarter 2007 Earnings Release Conference Call Webcast
4. Webcast Alert: Transgenomic Inc. Announces Fourth Quarter 2007 Earnings Release Conference Call Webcast
5. Transgenomic Appoints David Pauluzzi to Board of Directors
6. Transgenomic, Inc. Forms Scientific Advisory Board
7. Webcast Alert: Transgenomic Inc. Announces Third Quarter 2007 Earnings Release Conference Call Webcast
8. Transgenomic, Inc. Reports Second Quarter 2007 Results
9. Braemar Introduces the ER920W Wireless Cardiac Arrhythmia Monitor
10. LI-COR Biosciences Introduces Near-Infrared Small Animal Imager
11. SAFC Hitech Introduces Large Scale Bubbler for Compound Semiconductor Production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... Earlier this year, the Capillus272Pro™ received FDA ... adult men and women with androgenic alopecia (AGA) having ... IIa-V and Fitzpatrick Classification of Skin phototypes I-IV. ... and under-deliver, FDA Clearance underscores the safety and efficacy ... than 80 million men and women who suffer with ...
(Date:3/27/2015)... The consumption of compound fertilizers (NPK) fertilizers declined ... prices in 2008. However, the situation has stabilised afterwards, ... momentum now. , To date, the world annual production ... tonnes. No considerable growth was registered in the market ... 2012-2013, registering 11% growth as against the period of ...
(Date:3/27/2015)... , 27. März 2015  Peter ... in Biomedical Science für seine bahnbrechende Arbeit ... zwischen Zellkompartimenten transportiert werden, sowie für die ... zur Reaktion auf Stress nutzen, der mit ... Walter ist Professor für Biochemie an der ...
(Date:3/27/2015)...  Neogen Corporation (NASDAQ: NEOG ) announced today ... plan in accordance with Securities and Exchange Commission rule ... Neogen Corporation, is a minority owner of this entity ... Herbert does not have control of this entity, ... only for a portion of the shares owned by ...
Breaking Biology Technology:Dr. Robert Leonard Applauds FDA Clearance of Capillus272Pro™ Hair Loss Laser Cap 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 2Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 4Neogen CEO adopts 10b5-1 Trading Plan 2
... L.P., a subsidiary of Mylan Inc. (Nasdaq: ... market and distribute EMSAM(R) in the U.S. EMSAM, a ... which was approved by the U.S. Food and Drug ... depressive disorder. EMSAM previously was marketed and distributed by ...
... digital templating solution from Orthocrat. Using TraumaCad, UPMC Mercy,s ... within the UPMC enterprise. , ... ... today that UPMC Mercy, part of the UPMC global health ...
... 28 Cytopia Limited (ASX: CYT) announced that it will present ... CYT997, at the Annual Meeting of the American Society of Clinical ... clinical investigators for the program, will be presenting the poster in ... Therapeutics - Vascula ...
Cached Biology Technology:Dey L.P. to Market EMSAM(R) Skin Patch for Treatment of Major Depressive Disorder 2Orthocrat Announces Successful Implementation of TraumaCad at UPMC Mercy 2Orthocrat Announces Successful Implementation of TraumaCad at UPMC Mercy 3Oral VDA CYT997 - Phase I Clinical Trial Presentation at ASCO 2
(Date:3/11/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/3p32qm/access_control ) has ... by Product, Application & By Geography - Global Forecast ... , This report predicts that the access ... 2020, with an estimated CAGR of 10.6%. ... such as contact cards & readers, contactless cards & ...
(Date:3/10/2015)... 2015 Transforming How We Look ... Medicine in Human Space Flight" by Michael ... , Ph.D. was recently featured by Springer Science Media, highlighting ... Specifically, "Personalized Medicine in Human Space Flight" ... in 2013 and 2014 from Springer in the journal ...
(Date:3/5/2015)... 5, 2015 In Brazil , ... already using these solutions and 42 percent planning to invest ... approximately 25 percent of the companies will be investing in ... majority of companies in the region are currently opting for ... model will command significant attention in the coming years. This ...
Breaking Biology News(10 mins):Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 3Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 4
... at an alarming rate compared with other species, according to ... The rate of extinctions increased noticeably after 1950, although ... of extinct species has grown by 25 percent since 1989. ... US Geological Survey, examines North American freshwater fish extinctions from ...
... 2012 Scientists already know that the tiny hairs on ... vertical surfaces. Now, University of Akron researchers are unfolding clues ... to create a synthetic adhesive that sticks when moist or ... the sole of a gecko toe, and the pad repels ...
... along the ground by alternately squeezing and stretching muscles ... each wave of contractions. Snails and sea cucumbers also ... our own gastrointestinal tracts operate by a similar action, ... the stomach. Now researchers at MIT, Harvard University ...
Cached Biology News:Gecko feet hold clues to creating bandages that stick when wet 2Soft autonomous robot inches along like an earthworm 2Soft autonomous robot inches along like an earthworm 3
Affinity Purified Rabbit Anti-mouse sRANKL Biotinylated Polyclonal Antibody...
Mouse anti-IkBa/MAD-3 Class: Antibody Product Group: Signalling molecules and phospho-specific Antibody...
Mouse monoclonal [002-49] to C1s ( Abpromise for all tested applications). entrezGeneID: 716 SwissProtID: P09871...
Goat polyclonal to HSPC150 ( Abpromise for all tested applications). entrezGeneID: 29089...
Biology Products: