Navigation Links
Transgene's Therapeutic Vaccine TG4010 Shows Promising Preliminary Phase IIb Data in Advanced Non-Small Cell Lung Cancer
Date:1/10/2008

rter of 2008."

About TG4010 cancer vaccine

TG4010 (MVA-MUC1-IL2) uses the Modified Vaccinia Ankara virus vector, a poxvirus that combines distinguishing advantages for an optimized systemic vaccination:

- MVA is a highly attenuated strain which has been tested extensively in humans as a smallpox vaccine and is known to strongly stimulate the immune response to antigens.

- MUC1 is a major tumor-associated antigen that provides a viable target for vaccination.

- TG4010 expresses the entire MUC1 gene sequence and has the potential to generate an immune response to all antigenic epitopes of MUC1.

- The sequence coding for the cytokine Interleukin 2 (IL2) is included to help stimulate specific T-cell response.

About previous TG4010 clinical data

Non-controlled Phase II data are available at: http://www.transgene.fr/us/pdf/communique_presse/communiques_divers_2005/PR -U S_17-05-2005_ASCO_POUMON.pdf (Due to the length of this URL, it may be necessary to copy and paste this hyperlink into your Internet browser's URL address field. Remove the space if one exists.)

About Transgene

Transgene is a France-based biopharmaceutical company dedicated to the development of therapeutic vaccines and immunotherapeutic products in oncology and infectious diseases. The company has one product which has completed Phase II trials (TG4001/R3484), two compounds in Phase II trials (TG4010 and TG1042) and one compound in Phase I studies (TG4040). Transgene has concluded a strategic partnership agreement with Roche for the development of its TG4001/R3484 therapeutic vaccine to treat HPV-mediated diseases. Transgene has bio-manufacturing capacities for viral-based vectors and technologies available for out-licensing. Additional information about Transgene is available on the Internet at '/>"/>

SOURCE Transgene S.A.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. MedImmune Broadens Focus of Venture Capital Fund to Include New Therapeutic Areas
2. Mersana Therapeutics Appoints C. Boyd Clarke Chairman of the Board of Directors
3. Nektar Therapeutics President and CEO Howard W. Robin to Present At JPMorgan 26th Annual Healthcare Conference
4. Cell Therapeutics, Inc. (CTI) Hosts Conference Call to Discuss Update on Zevalin(R) Acquisition, CMS Reimbursement, and PIX301 Timeline
5. MultiCell Technologies To Increase Focus on Therapeutic Candidates
6. Sirnaomics Received Multiple Government Fundings For Its Multi-Targeted siRNA Therapeutics Programs
7. Co-Inventor of Amgens Aranesp(R) Technology Directs Worldwide Patent Strategy for Diffusion Pharmaceuticals First-in-Class Oxygen Enhancing Therapeutics
8. Pearl Therapeutics, Inc. Expands Its Senior Management Team With Top Talent in Clinical Development and Regulatory Affairs
9. Human Genome Sciences and Aegera Therapeutics Announce Licensing and Collaboration Agreement on Novel Anti-Cancer Drugs
10. House and Senate Pass Medicare Legislation to Freeze 2008 Reimbursement for Therapeutic Radiopharmaceuticals at 2007 Levels
11. Lonza Withdraws Majority of Claims in Patent Lawsuit Against Northwest Biotherapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... January 15, 2014 Look inside the ... items for the lab, from fluid handling to instruments ... to ship when you order. , Preferred Solutions ... , from the L/S® model for precise flow control ...
(Date:1/15/2014)... 15, 2014 ­ RedBrick Health , a fast-growing ... today announces that EmblemHealth , the ... is now providing the RedBrick Compass health assessment, combined ... all of its members. EmblemHealth is among the first ...
(Date:1/15/2014)... Houston, TX (PRWEB) January 15, 2014 ... Alzheimer’s disease, and about 1 in 3 seniors will ... ( source ). These jaw-dropping figures have shocked many ... function and, hopefully, help prevent these tragic age-related cognitive ...
(Date:1/15/2014)... 15, 2014 DTS Language Services, Inc ... Web Portal for Life Science organizations who need document translations. ... subject matter of their documents in advance with a selection ... time-to-delivery of translations, often a critical factor in clinical and ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2DTS Improves Efficiency for Life Science Document Translations 2
... , ... by the Johns Hopkins University School of Medicine Still Available On-Demand,Four out of Five Attendees ... ... CardioCareLive , the live virtual congress presented by the Johns Hopkins University School of ...
... GUANGZHOU, China , June 3 /PRNewswire-Asia/ -- China ... a,manufacturer, leading distributor and developer of Western pharmaceuticals,traditional Chinese medicines ("TCM"), ... Stockholders (the "Annual,Meeting") held on May 27, 2010 . , ... ...
... -Proceeds to support acceleration of CYT387 Phase II myelofibrosis study- , ... MISSISSAUGA, ON , June 3 /PRNewswire-FirstCall/ ... approximately US$3.2 million through a non-brokered private placement of 2,500,000 common ... no discount to the closing price of the shares on the NYSE Amex ...
Cached Biology Technology:CardioCareLive, the Largest Online Cardiology Conference, Attracts 2,300 Attendees and Enjoys 92% Recommendation Rate 2CardioCareLive, the Largest Online Cardiology Conference, Attracts 2,300 Attendees and Enjoys 92% Recommendation Rate 3CardioCareLive, the Largest Online Cardiology Conference, Attracts 2,300 Attendees and Enjoys 92% Recommendation Rate 4CardioCareLive, the Largest Online Cardiology Conference, Attracts 2,300 Attendees and Enjoys 92% Recommendation Rate 5China Medicine Announces Results of Annual Meeting of Stockholders 2China Medicine Announces Results of Annual Meeting of Stockholders 3YM BioSciences raises US$3.2 million in support of JAK 1/2 program 2YM BioSciences raises US$3.2 million in support of JAK 1/2 program 3YM BioSciences raises US$3.2 million in support of JAK 1/2 program 4
(Date:4/24/2014)... Munich have identified the structural features that enable ... and endogenous RNAs in living cells. , When ... metabolism and hijack cellular resources for the production ... viral RNA molecules that are delivered directly to ... synthesized in the host cell, and provide the ...
(Date:4/24/2014)... study representing the largest study of animal intelligence to-date finds ... self-control. , Published this week in the journal Proceedings ... part of a long history of research aimed at understanding ... do things like make and use tools, read social cues, ... Until now, most studies of animal intelligence have focused on ...
(Date:4/24/2014)... new insights into the make-up of tropical forests, a ... have revealed unprecedented detail of the size, age and ... maps with hundreds of field plots. , The ... amount of carbon each tree can store. This is ... trees are given a cash value according to their ...
Breaking Biology News(10 mins):Viral infections: Identifying the tell-tale patterns 2Viral infections: Identifying the tell-tale patterns 3Animals with bigger brains, broader diets have better self control 2Animals with bigger brains, broader diets have better self control 3Amazon rainforest survey could improve carbon offset schemes 2
... milk is the best source of food for infants. University ... second bestformula made from hazelnut oil. Casimir Akoh, ... in the College of Agricultural and Environmental Sciences, developed a ... structure of mother,s milk, which makes it better suited to ...
... helped biologists figure out why platelets, the cells that ... they are. Because platelets are important both for healing ... understanding of how they form and behave could have ... specific for blood clotting," said Alex Mogilner, professor of ...
... FRANCISCO May 25, 2012 -- Wells Fargo (NYSE:WFC) has ... Program a grant for $40,000 in support of marine ... the lack of engaging science education opportunities that inspire ... skills and adopt conservation attitudes and behaviors, and a ...
Cached Biology News:Hazelnuts improve infant formula 2Wells Fargo fosters environmental conservation through University of Miami's RJD program 2
... On-Demand Cytometry The Guava ... blue laser based multiparameter cytometer with built-in ... you can screen plates of cells and ... of manipulating multiple tubes or having the ...
Methylation analysis of gene promoters using bilsulfite treatment of DNA and comparative DNA sequence analysis. Probe design and PCR included....
... Galaxy LIMS, Sophisticated Bioinformatics , Proprietary primer ... offer individual sample sequencing of PCR products, ... or double strand publication quality. Primer ... interest is 1.3 to 7 kilobytes long. ...
GLP-compliant, CLIA-certified DNA sequencing service. ASQ and SQA certified quality assurance staff. Auditors welcome....
Biology Products: