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Transave Issued Key Composition of Matter Patent for ARIKACE™
Date:5/24/2010

MONMOUTH JUNCTION, N.J., May 24 /PRNewswire/ -- Transave Inc. today announced that the United States Patent and Trademark Office has issued an important composition of matter patent (U.S. Patent No. 7,718,189) for liposomal aminoglycoside formulations including its lead compound, ARIKACE™ (liposomal amikacin for inhalation). The company expects that the patent will provide exclusivity for ARIKACE until October 1, 2026.

"The issuance of this composition of matter patent significantly strengthens the intellectual property estate around ARIKACE and represents a valuable asset for Transave," said Tim Whitten, Transave's chief executive officer.  "We are continuing to secure and expand our proprietary position for ARIKACE which has the potential to become an important treatment for cystic fibrosis (CF) patients with Pseudomonas lung infections, non-CF bronchiectasis patients with Pseudomonas lung infections, and patients with nontuberculous mycobacteria (NTM) lung infections. We look forward to moving to Phase 3 as soon as possible."

The company also announced that the U.S. Patent office granted another patent (U.S. Patent No. 7,544,369) last year covering ARIKACE for the sustained release of antibiotic and once-daily treatment of Pseudomonas lung infections.

About ARIKACE™

ARIKACE is a form of the antibiotic amikacin, which is enclosed in nanocapsules of lipid called liposomes. This advanced pulmonary liposome technology prolongs the release of amikacin in the lungs while minimizing systemic exposure.  The treatment uses biocompatible lipids endogenous to the lung that are formulated into small (0.3 micron), neutral liposomes th
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SOURCE Transave, Inc.
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