Navigation Links
Tracking Huntington's disease through brain metabolism
Date:8/30/2013

Huntington's disease (HD) is a hereditary disorder characterized by the progressive onset of neurodegeneration. Children of HD patients have a 50% chance of inheriting the disease, but symptoms do not appear until middle age. While genetic testing reliably determines if children of HD sufferers are carriers of the disease, it cannot provide information as to when symptoms will appear. In this issue of the Journal of Clinical Investigation, David Eidelberg and colleagues at the Feinstein Institute of Medical Research, evaluated changes in the brain metabolism of a small group of preclinical HD carriers over the course of seven years and identified a metabolic network that is associated with HD progression. Measurable increases in the activity of this network were predictive of time to symptom onset. This study provides biomarkers for evaluating disease progression in HD carriers and supports incorporating this assessment into clinical trials of HD treatment.


'/>"/>

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Precision motion tracking Thousands of cells at a time
2. Precision motion tracking - Thousands of cells at a time
3. Tracking the Battle Against Breast Cancer With New Market Research
4. The First Patient Treated Using Celsense MRI Cell Tracking Technology
5. Best Practices for Tracking Tissue in the Healthcare Supply Chain, Webinar Hosted by Xtalks
6. CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard
7. Cedars-Sinai researchers, with stem cells and global colleagues, develop Huntingtons research tool
8. Avaxia Biologics, Inc. Raises $2.2 Million in First Closing of Series A Financing to Advance Oral Antibodies for Inflammatory Bowel Disease
9. The Foremost Expert on Morgellons Disease Highlights the Gravity of This Illness
10. A New Mechanism for Tau Protein Pathology in Alzheimers Disease was Presented by Oligomerix, Inc. at the Society for Neuroscience Annual Meeting
11. Roche NimbleGen and BGI Develop Advanced MHC Region Capture Technology for Human Disease and Biomedical Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... CLEVELAND , June 27, 2016  Global ... average 4.6 percent through 2020 to $7.2 billion.  ... (food and beverages, cleaning products, biofuel production, animal ... and biotechnology, diagnostics, and biocatalysts). Food and beverages ... gains driven by increasing consumption of products containing ...
(Date:6/27/2016)... , ... June 27, 2016 , ... ... bring innovative medical technologies, services and solutions to the healthcare market. The company's ... of various distribution, manufacturing, sales and marketing strategies that are necessary to help ...
(Date:6/24/2016)... SAN DIEGO , June 24, 2016 /PRNewswire/ ... that more sensitively detects cancers susceptible to PARP ... individual circulating tumor cells (CTCs). The new test ... of HRD-targeted therapeutics in multiple cancer types. ... therapies targeting DNA damage response pathways, including PARP, ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
Breaking Biology Technology:
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com , ... published the overview results from the Q1 wave of ... recent wave was consumers, receptivity to a program where ... with a health insurance company. "We were ... share," says Michael LaColla , CEO of Troubadour ...
(Date:4/26/2016)... LONDON , April 26, 2016 /PRNewswire/ ... Systems, a product subsidiary of Infosys (NYSE: ... partnership to integrate the Onegini mobile security platform ... http://photos.prnewswire.com/prnh/20151104/283829LOGO ) The integration ... security to access and transact across channels. Using ...
(Date:4/14/2016)... 2016 BioCatch ™, the ... announced the appointment of Eyal Goldwerger as ... Goldwerger,s leadership appointment comes at a time of ... deployment of its platform at several of the world,s ... discerns unique cognitive and physiological factors, is a winner ...
Breaking Biology News(10 mins):