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Topokine Commences Phase 2 Clinical Trial of XAF5 Gel to Reduce Submental Fat
Date:11/19/2013

nger, MD, PhD.  "Our research shows that patients would prefer a topical fat-reducing medication over therapies that cut or puncture the skin, which are the only treatments currently available.  The submental region is one of several body areas that we plan to target." 

About Topokine

Topokine Therapeutics is a clinical-stage biotechnology company developing topical prescription medications for non-invasive contouring of the face and body.  The company's lead program, XAF5 Gel, is a topical adipomodulatory product in Phase 2 clinical development for local reduction of excess subcutaneous fat.  Topokine's pipeline also includes XAF5 Ointment to treat steatoblepharon ("eye bags") and TAT4, a topical "filler" therapy to increase local tissue volume.

About Submental Fat

The area under the chin, also called the submental region, is an important determinant of facial attractiveness and youthfulness. Excess submental fat is very common and contributes to the appearance known as "double chin."  People with excess submental fat are more likely to report feeling self-conscious or appearing older or overweight.  Currently, the only available therapies to reduce submental fat require cutting or puncturing the skin.

Forward-Looking Statements

This press release contains forward-looking statements regarding the development of XAF5 Gel.  These statements are based on Topokine's current beliefs and expectations, but actual results may differ.

Media Contact: Matt Burke, Topokine, 6033150618, matt.burke@topokine.com

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