Navigation Links
Tool identifies infection clusters; rate of T cell drop not helpful in decision to start treating HIV
Date:2/22/2010

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000238

PRESS-ONLY PREVIEW OF THE ARTICLE: www.plos.org/press/plme-07-02-huang.pdf

CONTACT:
Susan Huang
University of California Irvine
Division of Infectious Diseases
101 The City Drive South
City Tower, Suite 400,
Orange, CA 92868-3217
United States of America
714-456-5047
sshuang@partners.org


Rate of T cell count drop not found helpful in deciding when to start HIV treatment

Published this week in open access journal PLoS Medicine, Marcel Wolbers (Wellcome Trust Major Overseas Program, Oxford University Clinical Research Unit) and colleagues find that the rate of CD4 T cell decline is not useful in deciding when to start HIV treatment.

Wolbers and colleagues analyzed data from several thousand cohort study participants with HIV (the CASCADE collaboration) and found that the CD4 cell slope does not improve the prediction of clinical outcome in patients with a CD4 cell count above 350 cells/μl. The authors state "the findings of this study strongly suggest that knowledge of the current CD4 cell count and an assessment of other established risk factors for progression to AIDS are sufficient when deciding whether to initiate cART in symptom-free HIV-positive patients."

Citation: Wolbers M, Babiker A, Sabin C, Young J, Dorrucci M, et al. (2010) Pretreatment CD4 Cell Slope and Progression to AIDS or Death in HIV-Infected Patients Initiating Antiretroviral TherapyThe CASCADE Collaboration: A Collaboration of 23 Cohort Studies. PLoS Med 7(2): e1000239. doi:10.1371/journal.pmed.1000239<
'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. Breakthrough research identifies how cells from pigs may cure diabetes
2. 2007 Global Survey Identifies Characteristics of Supply Chain Leaders
3. International team identifies 480 genes that control human cell division
4. Study by Leading Economist Identifies Potential for $378 Billion of Savings From Follow On Biologics
5. AGI Dermatics Clinical Data Identifies L-Ergothioneine as Part of Skins Natural Antioxidant System
6. Bionovo Identifies and Describes ER-beta Selective Compounds for the Treatment of Vaginal Dryness
7. Multinational deCODE Study Identifies New Link Between Inflammation and Heart Attack
8. Famed IT Investor and Director of 23andme Esther Dyson Identifies on IdeasProject.com Genetic Information as an Extremely Disruptive Force
9. New research identifies faster detection of viruses
10. Magellan to Receive Frost & Sullivan 2009 North American Product Innovation Award; Three-Minute LeadCare(R) II Test Identifies Children with Lead Poisoning
11. ChemoCentryx Identifies Novel Small Molecule C5aR Antagonist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2014)... 21, 2014) The yield so far is small, ... a low-energy, solution-based mineral substitution process to make a ... in electronics and alternative energy devices. , A paper ... the July 21 issue of the journal Inorganic ... in the inorganic and nuclear chemistry fields. The paper ...
(Date:7/20/2014)... 20, 2014 NSG Precision Cells ... optics, and spectrophotometer calibration standards for ... has released many products that have transformed the ... been their solid-state calibration standards. , NSG’s solid-state ... their release in 2008. NSG started manufacturing ...
(Date:7/18/2014)... mostly neutral. That is, most of the atoms ... of electrons in the outer parts of atoms equals ... As one or more electrons are plucked away ... stronger positive pull from the nucleus. This enhanced ... that those electrons are less vulnerable to the distractions ...
(Date:7/18/2014)... CHICAGO, Ill. , July 18, 2014 ... an infographic highlighting AbbVie and Shire,s complementary ... combination. A copy of the ... website at:  http://www.abbvieinvestor.com/phoenix.zhtml?c=251551&p=irol-disclaimer-documents ... Takeover Code, a copy of this announcement ...
Breaking Biology Technology:Oregon chemists eye improved thin films with metal substitution 2How NSG Precision Cells Spectrophotometer Calibration Standards Makes NIR Work Easier 2How NSG Precision Cells Spectrophotometer Calibration Standards Makes NIR Work Easier 3Highly charged ions 2Highly charged ions 3Highly charged ions 4NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION 2NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION 3NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION 4NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION 5NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION 6NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION 7
... Stevens Point, Wis. I sat down recently ... Burke during her third full day on the job to talk ... budget proposals and Wisconsins business scene. , , WTN: What are ... not only thrive, but be forward-looking? , , Mary Burke ...
... Madison, Wis. The Wisconsin Alumni Research ... University of Wisconsin-Madison, will be among the recipients of ... March 15 at a White House ceremony. The annual ... contributions to the Nations economic, environmental and social ...
... there is one area where I finally decided it's appropriate to ... are various articles and such that describe the "improved security" of ... is that at least half of us use no security, and ... my point. I took my laptop home from work, and set ...
Cached Biology Technology:Interview: New commerce secretary wants to keep momentum on jobs and business programs 2Interview: New commerce secretary wants to keep momentum on jobs and business programs 3Interview: New commerce secretary wants to keep momentum on jobs and business programs 4Screen-door security: most wireless networks left wide open 2Screen-door security: most wireless networks left wide open 3
(Date:7/21/2014)... a process that uses extracts from seeds of Moringa ... bacteria by 90% to 99%. The hardy trees that ... of Africa, Asia, and Latin America. , The protocol, ... Microbiology review, is low-cost and efficient, making it ... developing countries who are presently drinking highly turbid and ...
(Date:7/21/2014)... the strength of immune response, rather than with the ... the virus, might be a better way to reduce ... Washington, Seattle. She and her collaborators have now taken ... H7N9 influenza, and their work has already led to ... strain. The research is published ahead of print in ...
(Date:7/21/2014)... LAFAYETTE, IN Growers of annual bedding plant ... rooted transplants with a large stem diameter and ... susceptible to damage during shipping and transplant. To ... latitudes must rely on supplemental lighting from high-pressure ... shows that light-emitting diodes (LEDs) can give greenhouse ...
Breaking Biology News(10 mins):Potential new flu drugs target immune response, not virus 2LEDs shine in bedding plant production study 2
... , Johns Hopkins researchers have succeeded in teaching computers how ... activity, and to then use those commonalities to predict other ... help scientists better understand disease risk and cell development. ... Genome Research , published online on July 3 and Sept. ...
... led by Dr. Michael Lombardo, Prof. Simon Baron-Cohen and ... levels early in fetal development influence later sensitivity of ... individual,s susceptibility to engage in behavior, that in extremes, ... one sex more than the other. Although ...
... why plants and animals had a hard time recovering from ... ago. The reason: global warming. Because of environmental ... didn,t fully recover for 5 million years. The study ... was forever altered by giant volcanic eruptions in the Early ...
Cached Biology News:Computers 'taught' to ID regulating gene sequences 2Prenatal testosterone levels influence later response to reward 2Prenatal testosterone levels influence later response to reward 3After long-ago mass extinction, global warming hindered species' recovery 2After long-ago mass extinction, global warming hindered species' recovery 3After long-ago mass extinction, global warming hindered species' recovery 4
Human sVCAM-1/CD106 ELI-PAIR Kit...
GLP-1 (HYB 147-12)...
... Custom Synthesis Service provides you ... to knockdown any gene. We ... base pairs with terminal dT ... other lengths of your choice. ...
EDG-1 Western blot control Source: Cell Lysate Application: Western Blotting Control...
Biology Products: