Navigation Links
Tool identifies infection clusters; rate of T cell drop not helpful in decision to start treating HIV
Date:2/22/2010

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000238

PRESS-ONLY PREVIEW OF THE ARTICLE: www.plos.org/press/plme-07-02-huang.pdf

CONTACT:
Susan Huang
University of California Irvine
Division of Infectious Diseases
101 The City Drive South
City Tower, Suite 400,
Orange, CA 92868-3217
United States of America
714-456-5047
sshuang@partners.org


Rate of T cell count drop not found helpful in deciding when to start HIV treatment

Published this week in open access journal PLoS Medicine, Marcel Wolbers (Wellcome Trust Major Overseas Program, Oxford University Clinical Research Unit) and colleagues find that the rate of CD4 T cell decline is not useful in deciding when to start HIV treatment.

Wolbers and colleagues analyzed data from several thousand cohort study participants with HIV (the CASCADE collaboration) and found that the CD4 cell slope does not improve the prediction of clinical outcome in patients with a CD4 cell count above 350 cells/μl. The authors state "the findings of this study strongly suggest that knowledge of the current CD4 cell count and an assessment of other established risk factors for progression to AIDS are sufficient when deciding whether to initiate cART in symptom-free HIV-positive patients."

Citation: Wolbers M, Babiker A, Sabin C, Young J, Dorrucci M, et al. (2010) Pretreatment CD4 Cell Slope and Progression to AIDS or Death in HIV-Infected Patients Initiating Antiretroviral TherapyThe CASCADE Collaboration: A Collaboration of 23 Cohort Studies. PLoS Med 7(2): e1000239. doi:10.1371/journal.pmed.1000239<
'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. Breakthrough research identifies how cells from pigs may cure diabetes
2. 2007 Global Survey Identifies Characteristics of Supply Chain Leaders
3. International team identifies 480 genes that control human cell division
4. Study by Leading Economist Identifies Potential for $378 Billion of Savings From Follow On Biologics
5. AGI Dermatics Clinical Data Identifies L-Ergothioneine as Part of Skins Natural Antioxidant System
6. Bionovo Identifies and Describes ER-beta Selective Compounds for the Treatment of Vaginal Dryness
7. Multinational deCODE Study Identifies New Link Between Inflammation and Heart Attack
8. Famed IT Investor and Director of 23andme Esther Dyson Identifies on IdeasProject.com Genetic Information as an Extremely Disruptive Force
9. New research identifies faster detection of viruses
10. Magellan to Receive Frost & Sullivan 2009 North American Product Innovation Award; Three-Minute LeadCare(R) II Test Identifies Children with Lead Poisoning
11. ChemoCentryx Identifies Novel Small Molecule C5aR Antagonist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/16/2015)... Associates IRB, Inc., the industry-leading central IRB in customer ... Laboratory Drive in the heart of Research ... house review board and service staff, which will be ... service to clients. CBRE | ... while Capital Associates Management, LLC represented the landlord.   ...
(Date:4/16/2015)... 2015 According to the 2014 ... outside source was ranked first among the leading ... to lifting, pushing, pulling, holding, carrying, or throwing ... The David Round Company takes statistics like this ... hard to develop and design equipment that prevents ...
(Date:4/16/2015)... IA (PRWEB) April 16, 2015 ... announces that the prestigious 2015 Borlaug CAST Communication ... faculty member at Tuskegee University in Alabama. Award ... written material; public presentations; and/or the use of ... in all three areas. As a specialist in ...
(Date:4/16/2015)... /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the Company" ... pleased to announce that the Company will be presenting ... to be held in London, UK ... Mr. James Mellon , a director of Portage, ... key programs at its subsidiaries, Portage Pharmaceuticals Ltd. ("PPL"), ...
Breaking Biology Technology:Schulman IRB to Open Office in Research Triangle Park, N.C. 2The David Round Company Helps Companies Meet OSHA Standards by Combining Safety, Ergonomics, and Productivity 2The 2015 Borlaug CAST Communication Award Goes to Channapatna Prakash 2Portage to Present at Master Investor 2015 in London, UK 2Portage to Present at Master Investor 2015 in London, UK 3Portage to Present at Master Investor 2015 in London, UK 4
... - TOPIC: The state of the microRNA market and the ... current and potential impact on drug discovery, molecular, ... Tuesday, March 31, 2009, - TIME: ... - HOST: Christi Bird, Senior Research Analyst, Healthcare, ...
... March 30 BioVex Inc, a company developing new ... and infectious disease, announced today it has raised $40 ... private financing.The placement was led by Forbion Capital Partners, ... Agricole Private Equity, Harris & Harris Group, Innoven Partners, ...
... software for clinical research trials has named Jovianna DiCarlo President ... years experience driving new pharmaceutical therapeutics and devices through the ... to commercialization. , ... Frederick, MD ...
Cached Biology Technology:Frost & Sullivan Hosts Presentation on MicroRNAs: From Stem Cells and Cancer to Diagnostics and Therapeutics 2BioVex Raises $40 Million in First Close of Series F Financing 2BioVex Raises $40 Million in First Close of Series F Financing 3Jovianna DiCarlo Named ConsentSolutions, Inc. President & Chief Executive Officer 2
(Date:4/14/2015)... NEW YORK , April 14, 2015 /PRNewswire/ ... Fast IDentity Online (FIDO ® ) Alliance tm ... standards-based specifications. FIDO members commit to share technology ... authentication methods that are interoperable, more secure and ... specifications enable biometric identity verification that protects sensitive ...
(Date:4/13/2015)... YORK , April 13, 2015 ... by TechSci Research, "Global Biometrics Market Forecast & Opportunities, ... register a CAGR of around 14% till 2020. ... governments for large scale implementation and review of ... and launch of new products with greater efficiency, ...
(Date:4/10/2015)... , April 10, 2015 Research ... of the "Security Competitive Profiles - NEC" ... , NEC will continue to supply a ... the market, with a company focus on the development ... Winning opportunities in the Asia-Pacific ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2
... inside each cell, a little engine called RNA polymerase II ... the nucleus that get carried to production units in the ... researchers at the University of Michigan Medical School have shown ... for damage. When certain types of damage in DNA halt ...
... LAFAYETTE, Ind. - A biomedical engineer at Purdue University ... that promises to be more effective than standard CPR ... by 25 percent over the current method. A ... a success rate of 5 percent to 10 percent, ...
... (09/05/07)--It is well established that a child,s brain has ... the extent to which such plasticity exists in the ... and Johns Hopkins University have used converging evidence from ... adult visual cortex does indeed reorganize-and that the change ...
Cached Biology News:Enzyme alerts cell's powerful army to repair DNA damage 2Enzyme alerts cell's powerful army to repair DNA damage 3New CPR promises better results by compressing abdomen, not Chest 2New CPR promises better results by compressing abdomen, not Chest 3New CPR promises better results by compressing abdomen, not Chest 4Adult brain can change, study confirms 2
...
... This monoclonal antibody recognizes 30% ... unrelated individuals. It does not ... proteins lacking rheumatoid factor nor with ... be used in ELISA to detect ...
...
Human VEGF R2 (KDR) MAb (Clone 89106)...
Biology Products: