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ThromboGenics and BioInvent Announce Publication of Exciting Data on a Novel Class of Angiogenesis Inhibitors in Cell
Date:11/1/2007

ill be able to move this drug candidate into the clinic later this year, given its great therapeutic potential, not only in cancer, but also in severe eye diseases that are the major causes of blindness."

Svein Mathisen, CEO of BioInvent, added: "The data presented in this seminal paper more fully explains the tumour inhibition findings obtained in our preclinical program to date. Through this experimental work, the development path for the collaboration partners has been clarified and the potential for TB-403, as a novel treatment for cancer, has been emphasized. I feel confident in my belief that TB-403 will secure a prominent place in the oncology armoury."

About ThromboGenics

ThromboGenics is a biotechnology company focused on discovery and development of biopharmaceuticals for the treatment of a range of vascular diseases. The Company has several programs in Phase II clinical development including microplasmin, which is being evaluated as a treatment for vitreoretinal disorders and as a thrombolytic agent for vascular occlusive diseases, including acute stroke. ThromboGenics is also developing novel antibody therapeutics in collaboration with BioInvent International; these include TB-402 (Anti-Factor VIII), scheduled to enter Phase II clinical development in 2008, and TB-403 (Anti-PlGF), which is expected to proceed to Phase I clinical trials by the end of 2007. ThromboGenics has built strong links with the University of Leuven and has exclusive rights to certain therapeutics developed at the University. ThromboGenics is headquartered in Leuven, Belgium and has subsidiaries in Dublin, Ireland and New York, U.S. The Company is listed on Eurolist by Euronext Brussels under the symbol THR. More information is available at http://www.thrombogenics.com.

About BioInvent

BioInvent International AB, listed on The Nordic Exchange (OMXS:BINV), is a research-based pharmaceutical company
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SOURCE ThromboGenics NV
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