Navigation Links
ThromboGenics N.V. - Business Update
Date:5/13/2008

eye diseases such as retinal detachment, diabetic vitreous hemorrhage and macular hole. It is estimated that 600,000 vitrectomies are carried out annually worldwide.

Vitrectomy is used to induce a posterior vitreous detachment (PVD), which involves removing the vitreous from the eye. As microplasmin is a proteolytic enzyme, it is able to cleave the molecular structures which link the vitreous to the retina, meaning that it could facilitate, and in some cases even avoid, vitrectomy and therefore induce PVD without the risks inherent in the current surgical procedure.

The MIVI III trial, which has recruited a total of 125 patients, is designed to assess the safety and efficacy of administering microplasmin intravitreal injection 7 days prior to vitrectomy.

- ThromboGenics completed patient enrolment for its Phase II MITI IV trial

Microplasmin is also being studied for the treatment of acute ischemic stroke. In this indication, the fact that it is a direct-acting thrombolytic agent (breaks down blood clots) and is independent of plasminogen means that it could restore blood flow efficiently for a longer period after the stroke event, and with potentially fewer side-effects than other thrombolytic agents. The MITI IV study is placebo controlled and is evaluating the safety and preliminary efficacy of microplasmin in three different doses when administered intravenously to acute stroke patients between four and twelve hours after the onset of the stroke. This trial has recruited a total of 40 patients.

- In January, ThromboGenics announced that its novel anti-cancer antibody TB-403 had begun its initial Phase I clinical trial in Denmark.

TB-403 (Anti-PIGF) is a potential breakthrough in the treatment of cancer. It is a humanized monoclonal antibody that blocks the formation of the new blood vessels that are needed by solid tumours to support their growth. TB-403 therefore has the potential to minimise the growth and spread of ca
'/>"/>

SOURCE ThromboGenics NV
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related biology technology :

1. ThromboGenics - Business Update and Interim Results for the Seven Month Period Ending 30 June 2007
2. ThromboGenics Announces Successful Completion of Technology Transfer to Bharat Biotech for Production of Novel Thrombolytic Agent
3. ThromboGenics and BioInvent Announce Successful Completion of Phase I Clinical Trial of the Anticoagulant TB-402
4. ThromboGenics and BioInvent Announce Publication of Exciting Data on a Novel Class of Angiogenesis Inhibitors in Cell
5. ThromboGenics Presents Results of the Vitreomacular Traction Trial (MIVI IIT) at the American Society of Retina Specialists Annual Meeting
6. ThromboGenics Presents Results of the Phase I Trial of TB-402 at the Prestigious American Society of Hematology Annual Meeting
7. ThromboGenics and BioInvent Receive Approval to Begin Clinical Trials of TB-403 for the Treatment of Cancer
8. ThromboGenics Announces 2007 Full Year Results
9. ThromboGenics Completes Patient Enrolment of MITI IV Trial, a Phase II Study Evaluating the Safety and Preliminary Efficacy of Microplasmin in the Treatment of Acute Stroke
10. Boston Scientific to Explore Sale of Cardiac Surgery and Vascular Surgery Businesses
11. DuPont Leaders Brief Investors on Agriculture Businesses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... Sept. 23, 2014 News Facts ... India devoted to genome-based research for human health ... is taking a bite out of oral cancer with ... in India with the help of ... DataDirect Networks (DDN). , To fuel its cutting-edge cancer ...
(Date:9/23/2014)... , September 23, 2014 ... Closed System Transfer     Devices  (CSTD) ... partnership with Taiwanese distributor MedFront Medical Technology Corporation.  Equashield,s leading ... Taiwan , China ... the company continues to expand globally, and throughout ...
(Date:9/23/2014)... 2014 The Minnesota High Tech ... cellular modems , platforms and application-specific remote ... category for the 2014 Tekne Awards. The ... Minneapolis Convention Center on Thursday, November 13th. The ... have shown superior technology innovation and leadership. ...
(Date:9/22/2014)... DUBLIN , September 22, 2014 ... has announced the addition of the "Global ... offering.      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... are added to a system to detect and ... Reagents are generally used in laboratories to prepare, ...
Breaking Biology Technology:National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5Equashield Enters Taiwan Following Expansion to Australia, Japan, China 2NimbeLink Named Finalist for 15th Annual Tekne Awards 2NimbeLink Named Finalist for 15th Annual Tekne Awards 3Global Biotechnology Reagents Market 2014-2018: Key Vendors are Agilent, BD Biosciences, Bio-Rad, F. Hoffmann-La Roche, Sigma-Aldrich and Thermo Fisher 2Global Biotechnology Reagents Market 2014-2018: Key Vendors are Agilent, BD Biosciences, Bio-Rad, F. Hoffmann-La Roche, Sigma-Aldrich and Thermo Fisher 3
... Oconomowoc-based IT services provider, announced Tuesday a new market ... July 1, the campaign will expand the PDS presence ... recently received Specialized Technology Partner Certifications from Cisco in ... partner; IP Communications, IP Communications Express, and Wireless. In ...
... When Hurricane Dennis reached landfall in the Florida ... surprising a development. Weather Central Inc. , a ... almost the exact location two days earlier. , ,On ... a service used by more than 100 television stations ...
... incubates a branding process, which can result in a random ... extreme name identity, whereupon a major advertising process kicks in. ... that's how we refer to today's trendy branding. To avoid ... various branding tricks and become aware of the bigger risks. ...
Cached Biology Technology:Accidental naming 2Accidental naming 3Accidental naming 4
(Date:9/23/2014)... California , 23 de septiembre de ... lanzamiento del Sistema 1290 Infinity II LC, ... de Infinity en su portafolio de cromatografía ... científicos y directores de laboratorio que alcancen ... excepcional, facilidad de uso y capacidad de ...
(Date:9/22/2014)... A new American Cancer Society study suggests that ... previously known as the food stamp program, had ... non-participants. The authors say the findings emphasize the ... dietary quality of SNAP participants. , The SNAP ... with the resources to obtain a nutritionally adequate ...
(Date:9/22/2014)... also known as tapioca, has large starch-filled roots and ... Asia, and Latin America where corn and sugarcane are ... and processes designed to break down tapioca starch into ... such as glucose, fructose, or maltose syrup, tapioca may ... a Review article in Industrial Biotechnology , a ...
Breaking Biology News(10 mins):Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 2Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 3Federal food program puts food on the table, but dietary quality could be improved 2
... menstruating have a weakening in the quality of their bone ... getting plenty of weight-bearing exercise, a new study finds. The ... Annual Meeting in Boston. "Given the high number of ... fact that up to 24% of young female athletes may ...
... Using the only microscope of its kind in Australia, ... see the inner workings of T-cells, the front-line troops that ... germs and other invaders in our bloodstream. The discovery ... T-cells into action a breakthrough that could lead to ...
... 2011 The International Development Research Centre (IDRC) together with ... Sciences and Engineering Research Council of Canada (NSERC), and ... (SSHRC) today announce that five research teams have been ... International Research Initiative on Adaptation to Climate Change (IRIACC). ...
Cached Biology News:Athletic girls more likely to have impaired bone structure if menstrual cycle stops 2Scientists use super microscope to pinpoint body’s immunity 'switch' 2International research initiative on adaptation to climate change announces research awards 2International research initiative on adaptation to climate change announces research awards 3
ANXA11 Immunogen: ANXA11 (NP_001148, 406 a.a. ~ 506 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Anti-ADAM-12 (Meltrin Alpha); carboxy terminal end; rabbit host...
Anti-Flavocytochrome b Monoclonal, FITC Labeled Research Focus: other Storage: 4C Shipping Temperature: 4C...
Goat polyclonal to CHMP5 ( Abpromise for all tested applications). Antigen: Synthetic peptide: C-NKDGVLVDEFGLPQ, corresponding to C terminal amino acids 202-215 of Human CHMP5 Entrez GeneID: ...
Biology Products: