Navigation Links
Thermal Gradient Announces Breakthrough in Fast PCR Device Technology

ROCHESTER, N.Y., Feb. 7, 2011 /PRNewswire/ -- Thermal Gradient, a Rochester, NY biotech company, announces a breakthrough in its fast PCR technology for molecular diagnostics.  PCR (polymerase chain reaction) is the preferred critical step in virtually all forms of DNA testing.

The company's latest generation of amplification devices has successfully developed and demonstrated the performance of PCR at speeds many times faster than conventional methods, achieving 8.5 decades of amplification (greater than 300 million times) in just eight minutes.  For the first time, these simple devices are being made from low cost materials suitable for high volume manufacturing processes.  The company believes that it now has the best platform for molecular testing that addresses ease of use, fast performance, and low cost operation.

The current generation of devices, developed under an NIH grant(1), are aimed at rapid point-of-care HIV testing in low resource settings.  As such, they need to be easy to use, appropriate for field deployment, work very fast, and be produced in very large quantities at very low unit cost.  By demonstrating that high performance can be achieved in devices fabricated with materials suitable for mass production processes the company has taken a major step toward those goals. With this early success, the company has committed to its first mass producible injection molded design.  Testing of these units is expected early in January of 2011.

These amplification devices are used in a cartridge that is already in development.  This cartridge will be a single use, disposable unit that integrates sample preparation from whole blood, PCR amplification, and real-time detection.  The instrument that will process these cartridges is also under development.

(1) Award Number R44AI089389 from the National Institute Of Allergy and Infectious Diseases. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Allergy And Infectious Diseases or the National Institutes of Health.CONTACT: Joel

SOURCE Thermal Gradient Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Thermal-powered, insect-like robot crawls into microrobot contenders ring
2. With support, graphene still a superior thermal conductor
3. Paratherm's New GLT Heat Transfer Fluid: Thermally Stable & Lower Minimum Startup Temperatures
4. WeylChem Avoids Process Safety and Thermal Hazard Analysis Risks by Studying Heat Generation at the Click of one Button
5. New geothermal heat extraction process to deliver clean power generation
6. Calorimeters and Thermal Analysis Equipment Market to Exceed $539 Million by 2012, According to New Report by Global Industry Analysts
7. Process Safety and Thermal Hazard Analysis Fall Webinar Series presented by METTLER TOLEDO
8. BellBrook Labs Launches Groundbreaking New Microplate for High Content Chemotaxis Assays in a Stable Gradient
9. Celtic Pharma Announces Presentation of Preclinical Data at the 69th Annual Meeting of the AAD in New Orleans
10. Fuisz Pharma Announces Patented Communication of Analyte Information Between Microchip Containing Smart Tablet and a Body Fluid Analyzer
11. MetaMorphix, Inc. Announces Sale
Post Your Comments:
(Date:6/24/2016)... , June 24, 2016  Regular discussions on a ... take place between the two entities said Poloz. ... Ottawa , he pointed to the country,s ... the federal government. ... said, "Both institutions have common economic goals, why not sit ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... of its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with ... in this eBook by providing practical tips, tools, and strategies for clinical researchers. ...
(Date:6/23/2016)... -- A person commits a crime, and the detective uses ... criminal down. An outbreak of foodborne illness makes ... uses DNA evidence to track down the bacteria that caused ... not. The FDA has increasingly used a complex, cutting-edge technology ... Put as simply as possible, whole genome sequencing is a ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
Breaking Biology Technology:
(Date:5/20/2016)... , May 20, 2016  VoiceIt is excited ... with VoicePass. By working together, VoiceIt ...  Because VoiceIt and VoicePass take slightly different approaches ... increases both security and usability. ... about this new partnership. "This marketing ...
(Date:4/28/2016)... and BANGALORE, India , April ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... today announced a global partnership that will provide ... to use mobile banking and payment services.      ... a key innovation area for financial services, but it also ...
(Date:4/15/2016)... CHICAGO , April 15, 2016  A ... companies make more accurate underwriting decisions in a ... offering timely, competitively priced and high-value life insurance ... health screenings. With Force Diagnostics, rapid ... and lifestyle data readings (blood pressure, weight, pulse, ...
Breaking Biology News(10 mins):